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Low electrical resistance Properties of Acupoints:Roles of NOergic Signaling Molecules and Neuropeptides in skin electrical Conductance

引用

Chinese Journal of Integrative Medicine 2021年第8期27卷 563-569页

作者： MA Sheng-xing Lundquist Institute for Biomedical Innovation at Harbor University of California at Los Angeles(UCLA)Medical Center and Department of Obstetrics and Gynecology David Geffen School of Medicine at UCLA and Harbor-UCLA Medical CenterTorranceCA 90502United States

Early studies from several independent laboratories demonstrated that acupoints possess the characteristics of low electrical *** devices are developing to increase the reliability of electrical skin impedance measurements for counteracting the factors including skin dryness,skin thickness,size of the sensing electrode,pressure applied on the electrode,interelectrode distance,room temperature,and *** studies have identified that blood vessels,hair follicles,and nervous components are enhanced in the meridians/acupoints,which represent areas of potentially high neuronal *** evidence shows that nitric oxide(NO)concentrations are enhanced in skin acupoints/meridians.L-arginine-derived NO synthesis modifies skin norepinephrine(NE)synthesis/release in acupoints/meridians,and NO-NE activations play an important role in mediating the skin conductance responses to electrical *** signaling molecules interact with gap junction and transient receptor potential vanilloid *** studies reported that the high conductance at acupoints is a result of the release of the neuropeptides substance P and calcitonin gene-related peptide during neurogenic inflammation in the referred pain *** body conditions caused considerable changes in skin conductance or impedance at *** systematic research with an improved equipment and research design to avoid the influencing factors are requested for a definite answer in this field,the results from anatomical and biochemical studies consistently show that acupoints exist higher levels of nervous components,and NOergic signaling molecules and neuropeptides involved in the skin low resistance at *** increased interest in the acupoints/meridians has led to an open-minded attitude towards understanding this system,which is fundamental important to establish the valid aspects of scientific basis of Chinese medicine mechanisms and therapies.

关键词： acupuncture points skin electric resistance nitric oxide norepinephrine transient receptor potential vanilloid type-1 neuropeptides

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