检索结果-南通市图书馆

Pancreatic neuroendocrine tumor detected by technetium-99m methoxy-2-isobutylisonitrile single photon emission computed tomography/computed tomography:A case report

引用

World Journal of Clinical Cases 2023年第12期11卷 2825-2831页

作者： Chang-Jiang Liu Hua-Jun Yang Yan-Chun Peng De-Yu Huang Department of Nuclear Medicine Xingyi People’s HospitalXingyi 562400Guizhou ProvinceChina Department of Pulmonary and Critical Care Medicine Xingyi People’s HospitalXingyi 562400Guizhou ProvinceChina Department of Hepatobiliary Pancreatic and Splenic SurgeryXingyi People’s HospitalXingyi 562400Guizhou ProvinceChina Department of Pathology Xingyi People’s HospitalXingyi 562400Guizhou ProvinceChina

BACKGROUND Pancreatic neuroendocrine tumors(NETs)account for about 1%–2%of pancreatic tumors and about 8%of all NETs.computed tomography(CT),magnetic resonance imaging,and endoscopic ultrasound are common imaging modalities for the diagnosis of pancreatic NETs.Furthermore,somatostatin receptor imaging is of great value for diagnosing pancreatic NETs.Herein,we report the efficacy of technetium-99m methoxy-2-isobutylisonitrile(99mTc-MIBI)single photon emission CT(SPECT)/CT for detecting pancreatic NETs.CASE SUMMARY A 57-year-old woman presented to our hospital with a 1-d history of persistent upper abdominal distending pain.The distending pain in the upper abdomen was aggravated after eating,with nausea and retching.Routine blood test results showed a high neutrophil percentage,low leukomonocyte and monocyte percentages,and low leukomonocyte and eosinophil counts.Amylase,liver and kidney function,and tumor markers alpha-fetoprotein,carcinoembryonic antigen,and cancer antigen(CA)125,CA72-4,CA19-9,and CA153 were normal.Abdominal CT showed a mass,with multiple calcifications between the pancreas and the spleen.The boundary between the mass and the pancreas and spleen was poorly defined.Contrast-enhanced CT revealed that the upper abdominal mass was unevenly and gradually enhanced.99mTc-MIBI SPECT/CT revealed that a focal radioactive concentration,with mild radioactive concentration extending into the upper abdominal mass,was present at the pancreatic body and tail.The 99mTc-MIBI SPECT/CT manifestations were consistent with the final pathological diagnosis of pancreatic NET.CONCLUSION 99mTc-MIBI SPECT/CT appears to be a valuable tool for detecting pancreatic NETs.

关键词： Neuroendocrine tumors Pancreas Tc-99m-Methoxy-2-isobutylisonitrile single photon emission computed tomography X-ray computed tomography Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Positron emission computed tomography/single photon emission computed tomography in Parkinson disease

引用

Chinese Medical Journal 2020年第12期133卷 1448-1455页

作者： Nian-Ting Yao Qian Zheng Zi-Qian Xu Jian-Hong Yin Lin-Guang Lu Qi Zuo Su Yang Chun-Lin Zhang Ling Jiao Guizhou Medical University GuiyangGuizhou 550004China Department of Neurology The Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou 550004China Department of Biology Guizhou Medical UniversityGuiyangGuizhou 550004China

Parkinson disease(PD)is the second-most common neurodegenerative disorder.Its main pathological mechanism is the selective degeneration and deletion of dopaminergic neurons in the dense part of the substantia nigra and the damage of dopaminergic neurons caused by the abnormal deposition of a Lewy body,leading to a decreased dopamine level.Positron emission computed tomography(PET)/single photon emission computed tomography(SPECT)is a molecular imaging technology that can directly or indirectly reflect changes in molecular levels by using a specific tracer.With the research and development on the tracers of related enzymes for labeling dopamine transporter and dopamine receptor and for being involved in dopamine formation,this imaging technology has been applied to all aspects of PD research.It not only contributes to clinical work but also provides an important theoretical basis for exploring the pathological mechanism of PD at a molecular level.Therefore,this review discusses the application value of PET/SPECT in PD in terms of early diagnosis,disease severity evaluation,clinical manifestations,differential diagnosis,and pathological mechanism.

关键词： Parkinson disease Positron emission computed tomography single photon emission computed tomography Dopamine transporter ^18F-fluorodeoxyglucose

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quantification of Tc-99m-ethyl cysteinate dimer brain single photon emission computed tomography images using statistical probabilistic brain atlas in depressive end-stage renal disease patients:Correlation with disease severity and symptom factors

引用

Neural Regeneration Research 2012年第27期7卷 2151-2159页

作者： Heeyoung Kim In Joo Kim Seong-Jang Kim Sang Heon Song Kyoungjune Pak Keunyoung Kim Department of Nuclear Medicine Pusan National University HospitalBusanRepublic of Korea Biomedical Research Institute Pusan NationalBusanRepublic of Korea Department of Internal Medicine Pusan National University HospitalBusanRepublic of Korea

This study adapted a statistical probabilistic anatomical map of the brain for single photon emission computed tomography images of depressive end-stage renal disease patients. This research aimed to investigate the relationship between symptom clusters, disease severity, and cerebral blood flow. Twenty-seven patients （16 males, 11 females） with stages 4 and 5 end-stage renal disease were enrolled, along with 25 healthy controls. All patients underwent depressive mood assessment and brain single photon emission computed tomography. The statistical probabilistic anatomical map images were used to calculate the brain single photon emission computed tomography counts. Asymmetric index was acquired and Pearson correlation analysis was performed to analyze the correlation between symptom factors, severity, and regional cerebral blood flow. The depression factors of the Hamilton Depression Rating Scale showed a negative correlation with cerebral blood flow in the left amygdale. The insomnia factor showed negative correlations with cerebral blood flow in the left amygdala, right superior frontal gyrus, right middle frontal gyrus, and left middle frontal gyrus. The anxiety factor showed a positive correlation with cerebral glucose metabolism in the cerebellar vermis and a negative correlation with cerebral glucose metabolism in the left globus pailidus, right inferior frontal gyrus, both temporal poles, and left parahippocampus. The overall depression severity （total scores of Hamilton Depression Rating Scale） was negatively correlated with the statistical probabilistic anatomical map results in the left amygdala and right inferior frontal gyrus. In conclusion, our results demonstrated that the disease severity and extent of cerebral blood flow quantified by a probabilistic brain atlas was related to various brain areas in terms of the overall severity and symptom factors in end-stage renal disease patients.

关键词： single photon emission computed tomography end-stage renal disease depression statisticalprobabilistic brain atlas disease severity cerebral blood flow symptom brain neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluating the Effectiveness of Electro-Acupuncture as A Treatment for Childhood Autism Using single photon emission computed tomography

引用

Chinese Journal of Integrative Medicine 2014年第1期20卷 19-23页

作者：赵正勤贾少微胡疏孙雯 Department of Nuclear Medicine Peking University Shenzhen Hospital

Objective：To explore the effectiveness of electro-acupuncture（EA）in the treatment of childhood autism（CA）and evaluate its effectiveness using single photon emission computed tomography（SPECT）.Methods：A total of 55 CA patients（4.52±2.73 years）were enrolled in this study.All patients received EA treatments and were examined by SPECT before and after treatments.Results：Following treatment,the intracerebral multiple focal radioactivity distribution defect areas of CA patients were observed to be partially filled.Specifically,significant differences in the ratios of regional cerebral blood flow and global cerebral blood flow before（Fb）and after（Fe）EA treatment in different lesions were observed（in the left prefrontal cortex,t=5.01,P〈0.01;in the right prefrontal cortex,t=2.32,P〈0.05;in the left temporal lobe,t=4.54,P〈0.01;in the right temporal lobe,t=2.90,P〈0.05;in the left Broca’s area,t=5.82,P〈0.01）.After EA treatment,the patients exhibited symptomatic relief.Conclusion：EA is useful to treat CA and SPECT can be used to evaluate the effectiveness of this treatment.

关键词： electro-acupuncture single photon emission computed tomography childhood autism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Deep brain stimulation of the subthalamic nucleus treats Parkinson's disease through enhancing metabolic activity of the corpus striatum Verification by single photon emission computed tomography and positron emission tomography

引用

Neural Regeneration Research 2010年第6期5卷 405-410页

作者： Yiqun Cao Xiaoping Zhou Zhifeng Zhang Xiaowu Hu Xiufeng Jiang Department of Neurosurgery Changhai Hospital Second Military Medical University of Chinese PLA Shanghai 200433 China Department of Nuclear Medicine Changhai HospitalSecond Military Medical University of Chinese PLA Shanghai 200433 China

BACKGROUND： Subthalamic nucleus deep brain stimulation （STN DBS） for Parkinson＇s disease （PD） has achieved good effects, but to date the mechanism of STN DBS remains poorly understood STN DBS may increase dopamine levels or metabolic activity of the corpus striatum. OBJECTIVE： To validate the effects of STN DBS on dopamine metabolism and glucose metabolism in the corpus striatum of hemiparkinsonian monkeys using single photon emission computed tomography （SPECT） and position emission tomography （PET）. DESIGN, TIME AND SET＇rING： A controlled animal study was performed at the Neurosurgery Laboratory, Changhai Hospital of the Second Military Medical University of Chinese PLA between January 2004 and December 2007. METHODS： Hemiparkinsonism was induced in adult Rhesus Macaque monkeys, which exhibit similar characteristics of PD in humans, through unilateral internal carotid artery infusion of 1-methy-4-phenyl-1, 2, 3, 6-tetrahydropyrindine. Following model establishment, stimulation electrodes were implanted in the right STN, and chronic high-frequency stimulation （60 μs pulse width, 130 Hz frequency, and 1.5-2.0 V pressure） was performed. MAIN OUTCOME MEASURES： The changes in dopamine transporter （DAT）, D2 receptor （D2R）, and glucose metabolism in the corpus striatum following STN DBS were observed using SPECT and PET. RESULTS： SPECT examination showed that DAT specific binding in the right corpus striatum was increased at 3 months after DBS compared with prior to stimulation, and D2R specific binding in the right corpus striatum gradually decreased near levels on the left （non-electrode-implanted） side within 3 months after DBS. PET examination showed that the glucose metabolism in the right corpus striatum was markedly increased at 3 months after effective DBS. Hemiparkinsonism monkeys showed improved left limb rigidity, increased activities, and stable gait under chronic high-frequency stimulation. CONCLUSION： STN DBS increased striatal DAT, decreased D2R, and enhanced glucose metabolism, suggesting that chronic,

关键词： subthalamic nucleus deep brain stimulation Parkinson＇s disease monkey single photon emission computed tomography positron emission tomography neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Progress in the application of molecular imaging inpsychiatric disorders

引用

Psychoradiology 2023年第1期3卷 73-86页

作者： Jia Tan Guangying Zhang Jiaqi Hao Huawei Cai Dingping Wu Zhuoxiao Su Beibei Liu Min Wu Department of Radiology and Huaxi MR Research Center(HMRRC) Functional and Molecular Imaging Key Laboratory of Sichuan Pro vinceWest China HospitalSic huan Univ ersityChengdu 610041China Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengdu 610041China Department of Radiology Banan People’s HospitalChongqing Medical UniversityChongqing 400037China Department of Nuclear Medicine and Laboratory of Clinical Nuclear Medicine West China HospitalSichuan UniversityChengdu 610041China

Psychiatric disorders have always attracted a lot of attention from researchers due to the difficulties in their diagnoses and treatments.Molecular imaging,as an emerging technology,has played an important role in the researchers of various diseases.In recent years,molecular imaging techniques including magnetic resonance spectroscopy,nuclear medicine imaging,and fluorescence imaging have been widely used in the study of psychiatric disorders.This review will briefly summarize the progression of molecular imaging in psychiatric disorders.

关键词： molecular imaging psychiatric disorders magnetic resonance spectroscopy fluorescent molecular probe positron emis-sion computed tomography single photon emission computed tomography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regional cerebral blood flow in children with autism spectrum disorders： a quantitative 99mTc-ECD brain SPECT study with statistical parametric mapping evaluation

引用

Chinese Medical Journal 2011年第9期124卷 1362-1366页

作者： YANG Wen-han JING Jin XIU Li-juan CHENG Mu-hua WANG Xin BAO Peng WANG Qing-xiong Faculty of Child and Maternal Health School of Public Health Sun Yat-sen University Guangzhou Guangdong 510080 China 3rd Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Health Care Guangzhou Women and Children's Medical Center Guangzhou Guangdong 510623 China

Background Autism spectrum disorders （ASD）, which include autism, asperger syndrome （AS） and pervasive developmental disorder-not otherwise specified （PDD-NOS）, are devastating neurodevelopmental disorders of childhood resulting in deficits in social interaction, repetitive patterns of behaviors, and restricted interests and activities. single photon emission computed tomography （SPECT） is a common technique used to measure regional cerebral blood flow （rCBF）. Several studies have measured rCBF in children with ASD using SPECT, however, findings are discordant. In addition, the majority of subjects used in these studies were autistic. In this study, we aimed to investigate changes in rCBF in children with ASD using SPECT.Methods A Technetium-99m-ethyl cysteinate dimmer （99mTc-ECD） brain SPECT study was performed on an ASD group consisting of 23 children （3 girls and 20 boys; mean age （7.2±3.0） years） who were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, 4th edition （DSM-Ⅳ） criteria and an age-matched control group with 8children （1 girl and 7 boys, mean age （5.5±2.4） years）. Image data were evaluated with Statistical Parametric Mapping,5th version （SPM5）. A Student＇s t test for unpaired data was used to compare rCBF and asymmetry in the autism and corresponding control group. The covariance analysis, taking age as covariance, was performed between the ASD and control group.Results There was a significant reduction in rCBF in the bilateral frontal lobe （frontal poles, arcula frontal gyrus） and the bilateral basal ganglia in the autism group, and a reduction in the bilateral frontal, temporal, parietal, legumina nucleus and cerebellum in the AS group compared to the control. In addition, asymmetry of hemispheric hypoperfusion in the ASD group was observed. Inner-group comparison analysis revealed that rCBF decreased significantly in the bilateral frontal lobe （42.7%）, basal nucleus （24.9%） and temporal lobe （22.8%） in the autism group, and in the bilateral cerebellum （22.8%）, basal

关键词： autism spectrum disorders single photon emission computed tomography regional cerebral blood flow

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of intravascular laser phototherapy on delayed neurological sequelae after carbon monoxide intoxication as evaluated by brain perfusion imaging:A case report and review of the literature

引用

World Journal of Clinical Cases 2021年第13期9卷 3048-3055页

作者： Chuan-Ching Liu Chun-Sheng Hsu Hsin-Chen He Yuan-Yang Cheng Shin-Tsu Chang Department of Physical Medicine and Rehabilitation Taichung Veterans General HospitalTaichung 407Taiwan Department of Public Health and Institute of Public Health Chung Shan Medical UniversityTaichung 402Taiwan Department of Rehabilitation Science Jenteh Junior College of MedicineNursing and ManagementMiaoli 356Taiwan School of Medicine National Yang-Ming UniversityTaipei 112Taiwan Center for Geriatrics and Gerontology Taichung Veterans General HospitalTaichung 407Taiwan Department of Physical Medicine and Rehabilitation Tri-Service General HospitalSchool of MedicineNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND Delayed neurological sequelae(DNS)caused by carbon monoxide(CO)intoxication poses considerable treatment challenges for clinical practitioners.In this report,we used nuclear medicine imaging and the Mini-Mental State Examination(MMSE)to evaluate the effectiveness of intravascular laser irradiation of blood(ILIB)therapy for the management of DNS.CASE SUMMARY A 51-year-old woman presented to our medical center experiencing progressive bradykinesia,rigidity of limbs,gait disturbance,and cognitive impairment.Based on her neurological deficits,laboratory tests and imaging findings,the patient was diagnosed with delayed neurological sequelae of CO intoxication.She received intensive rehabilitation and ILIB therapy during 30 sessions over 2 mo after diagnosis.Brain single-photon emission computed tomography was performed both prior to and after ILIB therapy.The original hypoperfusion area in bilateral striata,bilateral frontal lobe,right parietal lobe,and bilateral cerebellum showed considerable improvement after completion of therapy.The patient’s MMSE score also increased markedly from 6/30 to 25/30.Symptoms of DNS became barely detectable,and the woman was able to carry out her daily living activities independently.CONCLUSION ILIB therapy could facilitate recovery from delayed neurological sequelae in patients with CO intoxication,as demonstrated by improved cerebral blood flow and functional outcomes in our patient.

关键词： Carbon monoxide poisoning Delayed neurological sequelae Intravascular laser irradiation of blood Redistribution single photon emission computed tomography Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regional cerebral blood flow imaging assessment of brain function reconstruction in elderly hemiplegia patients by body weight support treadmill training

引用

Neural Regeneration Research 2011年第17期6卷 1316-1321页

作者： Wenqing Wang Yongping Liu Diqing Wang Yanshuang Li Jinglai Hao Hongwei Zhang Sheng Bi Changshui Weng Department of Rehabilitation Medicine Affiliated Hospital of Chengde Medical College Chengde 067000 Hebei Province China Chengde Medical College Chengde 067000 Hebei Province China Department of Rehabilitation Medicine General Hospital of Chinese PLA Beijing 100853 China

The mechanism underlying body weight support treadmill training in elderly hemiplegic stroke patients is largely unknown. This study aimed to elucidate the changes of cortical blood flow in seven elderly patients with post-stroke hemiplegia before and after body weight support treadmill training by semi-quantitative analysis of regional cerebral blood flow assessed by single photon emission computed tomography. Body weight support treadmill training for 6 months was effective in improving cerebral blood flow and promoting the walking speed and balance recovery in elderly patients with post-stroke hemiplegia.

关键词： single photon emission computed tomography body weight support treadmill training elderly patients cerebral infarction neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Target imaging diagnosis of human brain glioma Clinical analysis of 40 cases

引用

CHINESE MEDICAL JOURNAL 1996年第1期109卷 93-6页

作者： Huang Qiang He Guangren Lan Qing Li Xiaonan Qian Zhiyuan Chen Jian Lu Zhaohui Du Ziwei DepartmentofNeurosurgery SecondAffiliatedHospital SuzhouMedicalCollege Suzhou

OBJECTIVE To establish a method for localization and qualitative diagnosis of glioma.METHODS The monoclonal antibody SZ-39 against human glioma was labelled with131I and injected intravenously into 40 patients with intracranial occupying lesions proved by X-CT. 72 hours after131I-McAb-SZ39 administration, cranial bone nuclide-imaging agent99mTc-MDP was injected intravenously, and the patients were examined by SPECT scan with dual nuclide double channel tomography and special software. On radio-immuno-image, the immunocomplex formed by specific conjugation of131I-McAb-SZ39 with target tissue was red, while the cranial bone incorporated with99mTc-MDP was green. The location of the immunocomplex area could be identified by the superimposition of the images.RESULTS 21 patients with positive targeting diagnosis of glioma showed the accuracy rate checked by SPECT was 81%(17/21) and by X-CT 48% (10/21). Seven patients with negative targeting diagnosis showed the accuracy rate checked by SPECT was 86%(6/7) and by X-CT 14% (1/7). Pathologically, the sensitivity of targeting SPECT to glioma was 94.5%(17/18) and that of X-CT 55%(10/18).CONCLUSIONS Targeting SPECT examination could be used for localization and qualitative diagnosis of glioma and make up the inadequacy of X-CT in the qualitative diagnosis of atypical incipient and recurrent glioma, meningioma, metastatic carcinoma, and inflammatory lesions of brain.

关键词： image diagnosis targeting single photon emission computed tomography Technetium Tc 99m Medronate qualitative diagnosis target organ Glioma wetware proprietary software accuracy rate

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：