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A case report on the relationship between treatment-resistant childhood-onset schizophrenia and an abnormally enlarged cavum septum pellucidum combined with cavum vergae

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Chinese Medical Journal 2012年第7期125卷 1349-1351页

作者： LIAO Zheng-luan HU Shao-hua XU Yi Dpartment of Mental Health First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouZhejiang 310003China

The treatment of refractory schizophrenia has been a clinical challenge for most psychiatrists; the possible reasons include diagnostic errors, medical conditions and brain dysgenesis. Here, we described a patient with childhood-onset schizophrenia who had severe psychiatric symptoms such as auditory hallucinations and persecutory delusions, and etc. We reexamined all his possible medical conditions and found that the patient had an abnormally enlarged cavus septum pellucidum （CSP） combined with cavum vergae （CV）（maximum length 〉30 mm）. Some reports suggested that abnormal CSP （length 〉6 mm） has a significant association with schizophrenia. However, abnormally large CSP or CSP/CV and related prognosis were reported rarely. This case suggested that abnormally enlarged CSP or CSP/CV may worsen the prognosis.

关键词： schizophrenia septum pellucidum

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Clinical and pathological characteristics of septum pellucidum tumor and choice of surgical approaches for its resection

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Chinese Medical Journal 2005年第10期118卷 812-816页

作者： WANGLei ZHANGMao-zhi ZHANGWei ZHAOShang-feng ZHAOJi-zong JIAJin-xiu DepartmentofNeurosurgery TiantanHospitalBeijing100050China

Background Tumor involving the septum pellucidum is uncommon. Surgery as the main therapeutic procedure for this lesion is a challenge to neurosurgeons. We analyzed the clinical characteristics and pathological features of septum pellucidum tumor in 41 patients and compared the curative effects of frontal transcortical, trans-sulcal and interhemispheric transcallosal approaches. Methods Clinical characteristics and the pathological features of septum pellucidum tumor were investigated retrospectively in 41 patients. The differences in postoperative residual rates, extents of tumors and resection of normal brain tissues after use of the three approaches in these patients were analyzed statistically. Results septum pellucidum tumor is more likely to attack young or middle-aged persons. The tumor mainly presents itself as a central neurocytoma or cerebral low-grade glioma in pathology and manifests as intracranial hypertension clinically. No difference was found in the extent of tumor resection but significant difference in the extent of normal brain tissue resection and in postoperative disability rate among the three approaches. The transcortical approach brought about the most serious injury to brain tissue and the highest disability rate, Whereas the frontal transcallosal approach the lightest injury and the lowest disability rate. The injury to brain tissue and the disability rate brought about by the front trans-sulcus approach were between the above two approaches. Conclusions Operation is still regarded the major treatment for septum pellucidum tumor. Transcallosal and trans-sulcus approaches are fit with the concept of minimally invasive surgery, and transcallosal approach is the first choice for septum pellucidum tumor.

关键词： septum pellucidum intracranial tumor central neurocytoma surgery minimal invasion

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Case Report of a septum pellucidum Cavernoma Surgically Resected via Inferior Parietal Approach and Short Literature Review

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Open Journal of Modern Neurosurgery 2016年第2期6卷 68-75页

作者： Constantinos Picolas Konstantinos Faropoulos Kyriaki Kekempanou Georgios Gatzounis Panarcadian General Hospital Neurosurgery Department Terma Erythrou Stavrou Tripoli Greece Patras University Hospital Neurosurgery Department Rio Patras Greece Patras University Hospital Pathology Department Rio Patras Greece

Background and Importance: Cavernomas of the septum pellucidum represent an extremely rare subtype of CNS cavernous angiomas which are a rare subtype of CNS tumors. Intraventricular cavernomas of the body of the lateral ventricle are usually treated by the transcallosal approach. Clinical Presentation: We present a case of a fifty-eight year old man with a septum pellucidum cavernoma successfully treated operatively by means of the inferior parietal transcortical transventricular approach. This unusual and scarcely documented tumor was situated at the posterior third of the septum pellucidum. The patient had a good recovery with no focal deficit. Conclusion: septum pellucidum cavernomas are extremely rare lesions. Inferior parietal transcortical approach is a safe alternative to the commonly used transcallosal approach for lesions of the posterior half of the septum pellucidum.

关键词： Septal Cavernoma septum pellucidum Transcallosal Approach Inferior Parietal Transcortical

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Spontaneous Resolution of A Cyst of The septum pellucidum:a Case Report

Spontaneous Resolution of A Cyst of The Septum Pellucidum:a ...

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2011年浙江省神经外科学学术年会

作者： Department of Neurosurgery,2nd Affiliated Hospital,School of Medicine,Zhejiang University,88# Jiefang Road,Hangzhou,Zhejiang,China,310006 Hong,Yuan MD Chen,Sheng MS Guo,Song-Xue MS Zhang,Jian-Min MD,PhD

septum pellucidum cysts are rare clinical findings.Although their optimal treatment remains controversial,large cysts causing hydrocephalus or neural compression should be treated surgically.However, spontaneous resolution can also occur.Herein,we present a case of a 38-year-old woman suffering from intermittent headache associate with an expanding cyst of the septum pellucidum.No surgical intervention was performed as hydrocephalus was not observed.After 16 months follow up,her symptom disappeared and MRI revealed that the cyst had disappeared.To the best of our knowledge,this is only the third reported case of spontaneous resolution of a septum pellucidum cyst,and suggests that a symptomatic septum pellucidum cyst is not absolute indication of surgical treatment.A conservative approach with close follow up with CT and MRI is strongly recommended unless the cyst causes obvious hydrocephalus or progressive neurological deterioration.

关键词： septum pellucidum Cyst Spontaneous resolution

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Spontaneous resolution of a cyst of the septum pellucidum: A case report

Spontaneous resolution of a cyst of the septum pellucidum: A...

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2011中华医学会神经外科学学术会议

作者： Yuan Hong1 Shen Chen1 Songxue Guo1 Jianmin Zhang1 1.Department of Neurosurgery, 2 nd Affiliated Hospital, School of Medicine, Zhejiang University,

关键词： septum pellucidum Cyst Spontaneous resolution.

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