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Synthesis of amphiphilic poly(fluorene) derivatives for selective imaging of Staphylococcus aureus

Science Bulletin 2018年第14期63卷 900-906页

作者： Ping He Fengting Lv Libing Liu Shu Wang Key Laboratory of Organic Solids Institute of ChemistryChinese Academy of Sciences Beijing 100190 China College of Chemistry University of Chinese Academy of Sciences Beijing 100049 China

Three amphiphilic poly（fluorene-co-phenylene） derivatives with different side chains （PFP-I, PFP-2, PFP- 3） were designed and synthesized for exploring their detection and imaging of pathogens. Upon incuba- tion with six kinds of different pathogens, it was found the three polymers could selectively interact with Staphylococcus oureus （S. aureus）. Their selective imaging towards S. aureus were thus realized. The selective imaging towards S. aureus was also confirmed even under the blend of microbes. PFP-3 shows stronger fluorescence imaging signal than PFP-1 and PFP-2. Zeta potential and isothermal titration microcalorimetry （ITC） tests demonstrated that both electrostatic interactions and hydrophobic interac- tions played important roles in the binding between PFPs and pathogens. Thus, amphiphilic PFP-3 exhi- bits great potential for specific imaging ors. aureus in a simple and rapid manner.

关键词： Conjugated polymers Pathogens S. aureus selective imaging

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Computer Forensics Framework for Efficient and Lawful Privacy-Preserved Investigation

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Computer Systems Science & Engineering 2023年第5期45卷 2071-2092页

作者： Waleed Halboob Jalal Almuhtadi Center of Excellence in Information Assurance King Saud UniversityRiyadh11653Saudi Arabia College of Computer and Information Sciences King Saud UniversityRiyadh11451Saudi Arabia

Privacy preservation(PP)in Digital forensics(DF)is a conflicted and non-trivial *** solutions use the searchable encryption concept and,as a result,are not efficient and support only a keyword ***,the collected forensic data cannot be analyzed using existing well-known digital *** research paper first investigates the lawful requirements for PP in DF based on the organization for economic co-operation and development OECB)privacy *** have an efficient investigation process and meet the increased volume of data,the presented framework is designed based on the selective imaging concept and advanced encryption standard(AES).The proposed framework has two main modules,namely selective imaging Module(SIM)and selective Analysis Module(SAM).The SIM and SAM modules are implemented based on advanced forensic format 4(AFF4)and SleuthKit open source forensics frameworks,respectively,and,accordingly,the proposed framework is evaluated in a forensically sound *** evaluation result is compared with other relevant works and,as a result,the proposed solution provides a privacy-preserving,efficient forensic imaging and analysis process while having also sufficient ***,the AFF4 forensic image,produced by the SIM module,can be analyzed not only by SAM,but also by other well-known analysis tools available on the market.

关键词： Digital forensics digital evidence AFF4 privacy preservation selective imaging

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