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Screening Coarctation of Aorta with Clinical and Echocardiographic Profiles in Infants:A Pilot Study

Congenital Heart Disease 2021年第2期16卷 159-170页

作者： Ruikun Zou Yifei Wang Chengcheng Pang Yunxia Sun Chen Chen Jian Zhuang Department of Neonatology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina Department of Maternal-Fetal Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangdong Province Key Laboratory of Structural Heart DiseaseGuangzhouChina Department of Cardiac Surgery Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of South ChinaGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina

Aim:To determine the profiles of clinical features including four-limb blood pressure(BP),saturations of peripheral oxygen(SpO2),and echocardiographic features in infants with coarctation of aorta(CoA)to facilitate congenital heart diseases ***:The charts of infants with CoA were retrospectively *** in-hospital infants suspected of congenital heart diseases by clinical teams were prospectively measured of four limbs BPs and SpO2 in a regional cardiac transferring center during 2013 and *** as a gold standard test was followed within 2 days after *** infants were divided into non-significant CoA group or significant CoA group based on the difference of BPs between right arm and lower *** of nonsignificant CoA were determined with multivariable logistic ***:One hundred thirty-three infants with CoA were *** BPs on upper limbs were higher than those on lower limbs(P=0.001).No statistical difference in SpO2 was found between four ***-three(39.8%)infants presented with significant ***-four infants presented with low SpO2 and 26 of 34 presented with non-significant *** ascending aorta diameter[0.070(95%CI:0.005–0.136),P=0.036]was an independent risk factors for non-significant ***(13.5%)infants with CoA didn’t present with any of the BP difference,low SpO2,murmur,or weak femoral ***:Less than half of the infants with CoA presented with a significant BP *** one fifth presented with low *** ascending aorta diameter was an independent factor for non-significant CoA.

关键词： Congenital heart disease coarctation of aorta screening blood pressure saturations of peripheral oxygen

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