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Effects of adaptation to handling on the circadian rhythmicity of blood solutes in Mongolian gerbils

Animal Models and Experimental Medicine 2019年第2期2卷 127-131页

作者： Xingchen Liu Xiang Zheng Yihan Liu Xiaoyan Du Zhenwen Chen School of Basic Medical Science Capital Medical University Beijing China Department of Laboratory Animal Capital Medical University Beijing China

The Mongolian gerbil has been widely used in many research fields and has been reported to be a diurnal laboratory animal. The circadian rhythmicity of these gerbils was investigated in the present study by measuring two hormones that show daily oscillations, cortisol and ACTH, in serum using ELISA kits. The levels of the two hormones were highest at 8:00 am and their rhythmic changes were similar to those in humans. In addition, the influence of stress of handling and blood collection on the physiological parameters of the gerbils was examined. After adaptation to handling for 1 week, some serum parameters in the animals changed. Handling and blood collection did not impact significantly on the following parameters: creatine kinase (CK), lactate dehydrogenase (LD), alanine aminotransferase (ALT), aspartate transaminase (AST), blood urea nitrogen (BUN), and albumin (ALB). However, blood glucose (GLU), total protein (TP) and globulin (GLB) significantly increased while creatinine (CRE) and albumin/globulin (A/G) significantly decreased after adaptation. This work further confirms that the Mongolian gerbil is a diurnal animal and also indicates that a suitable adaptation procedure is necessary for getting reliable results when performing experiments using these animals.

关键词： circadian rhythmicity diurnal animals handling adaptation Mongolian gerbils physiological parameters stress

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Influence of Climate and Tectonics on the Crystallization of Carnallite and Related Salts in the Congolese Atlantic Basin during the Lower Cretaceous, Republic of Congo

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Open Journal of Geology 2023年第1期13卷 51-71页

作者： Daphne Steimer Garcia Nkokani Milandou Hilaire Elenga Maurice Dieudonné Malounguila Nganga Mathurin Enama Mengong Center for Geological and Mining Research Brazzaville Republic of Congo Faculty of Science and Technology Geology Course Marien Ngouabi University Brazzaville Republic of Congo Newco Mining SA Pointe-Noire Republic of Congo

Lithological, petrographic, and morphoscopic studies were conducted on cuttings and cores from three boreholes drilled in the Loemé salt, Kanga site, Republic of the Congo, to determine 1) the preferential conditions for crystallization of carnallite and associated salts and 2) to reconstruct paleoenvironmental and paleoclimatic conditions at the time of sedimentation. Sequential analysis of logs, sedimentary structures, carnallitite facies and associated salts concluded to the existence of a potassic carnallitite lagoon basin with low water cover, on a very wide and extensive plateau, affected by coastal waves and swells resulting from successive collapses. This basin evolved in two phases: confined and then open. The regular stratifications of halite, the rhythmicity of the halite-carnallitite elementary sequences are characteristic of salts that precipitated in relatively stable brines. These salts are therefore tectonosedimentary. The brecciated facies of the carnallitites sometimes associated with tachyhydrite result from the evolution of these deposits into salt crusts reworked by the surges into subaquatic allochemical gravelly cords under water. These crusts mark stages of partial and complete drying of the basin in a very hot and arid climate. Prolonged exposure of halite brines as well as their homogenization by surges accelerated evaporation and their abrupt evolution into carnallite brines obstructing the fossilization of sylvite. The precipitation of tachyhydrite marks the final stage of the successive complete drying of the basin.

关键词： Potassium Lagoon Surges Stable Brines rhythmicity Elementary Sequences Salt Crusts Arid Climate Republic of the Congo

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