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Autologous platelet-rich-fibrin-induced revascularization sequelae:Two case reports Autologous platelet-rich-fibrin-induced revascularization sequelae:Two case reports

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World Journal of Stomatology 2019年第3期7卷 28-38页

作者： Ahmed M Eltawila Rania El Backly Department of Materials Science Institute of Graduate Studies and ResearchAlexandria UniversityAlexandria 21526Egypt Tissue Engineering Laboratories Faculty of DentistryAlexandria UniversityAlexandria 21411Egypt Endodontics Division Conservative Dentistry DepartmentFaculty of DentistryAlexandria UniversityAlexandria 21411Egypt

BACKGROUND A key requirement for biomimetic regeneration of tissues is a 3D scaffold.The gold standard scaffold for revascularization is the blood clot,however,an adequate blood clot cannot always be achieved in narrow canals or mature roots.Hereby,we document the effects of platelet-rich fibrin(PRF)for the regenerative endodontic treatment(RET)of two immature permanent teeth with necrotic pulps for up to 48 mo.CASES SUMMARY The first patient was a 22-year-old female with history of trauma in tooth#9 with a sinus tract and a large periapical lesion.The second was a 9-year-old male presenting with a badly decayed tooth#14.Both cases were treated with RET and PRF prepared from the patients’blood.PRF and its extract were used as a scaffold for RET.Patients were followed-up to 9 and 48 mo(4 years),respectively.Both patients,were asymptomatic after treatment.At the 9-mo-follow-up of case#1,there was radiographic evidence of periapical bone healing,however,the root apex was still open.In case#2,the roots exhibited apical closure and normal periapical bone architecture at 12-mo follow-up,while no root lengthening was observed.After 48 mo,case#2 showed extensive intracanal calcification in all root canals that complicated conventional root canal treatment.CONCLUSION RET with PRF and its extract could be used in revascularization of immature permanent teeth.However,proper case selection to comply with long-term follow-up is necessary and adverse events such as calcification and canal obliteration should be planned for.

关键词： revascularization Platelet-rich fibrin Dental pulp Regenerative endodontics Tooth Case report

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Morphological　and　functional　study　of　ischemic　left　ventricle　after　laser　transmural　revascularization

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Journal of Medical Colleges of PLA(China) 1996年第3期11卷 200-204页

作者：郜发宝黄志兰索丽萍乔宏庆刘维永汪钢

Ｍｏｒｐｈｏｌｏｇｉｃａｌａｎｄｆｕｎｃｔｉｏｎａｌｓｔｕｄｙｏｆｉｓｃｈｅｍｉｃｌｅｆｔｖｅｎｔｒｉｃｌｅａｆｔｅｒｌａｓｅｒｔｒａｎｓｍｕｒａｌｒｅｖａｓｃｕｌａｒｉｚａｔｉｏｎ￥ＧａｏＦａｂａｏ；ＨｕａｎｇＺｈ... 详细信息

Ｍｏｒｐｈｏｌｏｇｉｃａｌａｎｄｆｕｎｃｔｉｏｎａｌｓｔｕｄｙｏｆｉｓｃｈｅｍｉｃｌｅｆｔｖｅｎｔｒｉｃｌｅａｆｔｅｒｌａｓｅｒｔｒａｎｓｍｕｒａｌｒｅｖａｓｃｕｌａｒｉｚａｔｉｏｎ￥ＧａｏＦａｂａｏ；ＨｕａｎｇＺｈｉｌａｎ；ＳｕｏＬｉｐｉｎｇ；Ｑｉ...

关键词： laser coronary artery disease revascularization angiocardiography animal,experiment

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Ventriculocoronary artery bypass(VCAB):a new approach to myocardial revascularization

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外科研究与新技术 2005年第4期 322-325页

作者：孙林王永武 Department of Thoracic and Cardiovascular Surgery Tongji Hospital of Tongji UniversityShanghai 200065China

Nowadays,coronary artery bypass accounts for nearly half of the deaths in the developed world and 25% in the developing world.Percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) have become standard treatment for coronary artery disease.Direct revascularization from the left ventricle has already been studied in late 1960s. Recently some researchers reported a new approach to myocardial revascularization,ventriculo- coronary artery bypass (VCAB). In this paper we review the advance in experimental research and clinical research.

关键词： coronary artery disease treatment myocardial revascularization

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revascularization of isolated bone in dogs

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Chinese Medical Journal 1997年第11期 76-76页

作者：门保忠马承宣王素平李战国

ＲｅｖａｓｃｕｌａｒｉｚａｔｉｏｎｏｆｉｓｏｌａｔｅｄｂｏｎｅｉｎｄｏｇｓＭｅｎＢａｏｚｈｏｎｇ门保忠，ＭａＣｈｅｎｇｘｕａｎ马承宣，ＷａｎｇＳｕｐｉｎｇ王素平ａｎｄＬｉＺｈａｎｇｕｏ李战国ＯｂｊｅｃｔｉｖｅＴｏｄｉ... 详细信息

ＲｅｖａｓｃｕｌａｒｉｚａｔｉｏｎｏｆｉｓｏｌａｔｅｄｂｏｎｅｉｎｄｏｇｓＭｅｎＢａｏｚｈｏｎｇ门保忠，ＭａＣｈｅｎｇｘｕａｎ马承宣，ＷａｎｇＳｕｐｉｎｇ王素平ａｎｄＬｉＺｈａｎｇｕｏ李战国ＯｂｊｅｃｔｉｖｅＴｏｄｉｓｃｕｓｓｔｈｅｐｏｓｓｉｂｉｌｉ...

关键词：李战 revascularization bone isolated dogs 承宣保忠

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Coronary Physiology in the Management of CAD Patients: Position Paper Regarding the Current Scenario in India

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World Journal of Cardiovascular Diseases 2023年第11期13卷 795-810页

作者： Sridhar Kasturi Ramneek Kaur Manish Narang Surinder Kher Department of Cardiology Sunshine Heart Institute Secunderabad Hyderabad India Department of Medical Affairs Abbott Vascular Abbott Healthcare Pvt Ltd. Delhi India Asia Pacific & Japan Department of Medical Affairs Abbott Vascular Abbott Healthcare Pvt Ltd. Delhi India Independent Clinical Research Professional Bangalore India

Fractional flow reserve (FFR), a physiology-based diagnostic method, has emerged as an important decision-making tool in determining the borderline or intermediate coronary lesions requiring revascularization. As per the guidelines recommended by European and American cardiology associations, functional assessment of indeterminate lesions is to be considered strongly prior to PCI. However, in India, FFR continues to be a much-underutilized tool due to limited facilities, and many times, physicians are reluctant to advise FFR because of its time-consuming nature with additional cost implications of simple diagnostic tests. Notably, for stenoses ranging between 50% - 70% where the choice between revascularization and medication becomes ambiguous, FFR provides invaluable insight. Without such guidance, there is a risk of improper decisions and strategies while planning revascularization procedures, which might adversely influence clinical outcomes, escalation of the cost due to unnecessary procedures, and prolonged hospitalization as a result of simple vs complex procedures. Landmark studies have validated the efficacy of FFR in enhancing outcomes in coronary artery disease (CAD) patients, especially when paired with a coronary angiogram. This combination provides robust evidence of the functional significance of stenosis in stable CAD. Additionally, non-hyperemic pressure ratio indices correlate well with conventional FFR. Hence, adopting FFR-guided management can have transformative effects on the clinical and economic facets of treating severe CAD with intermediary lesions in Indian settings.

关键词： Coronary Physiology Fractional Flow Reserve Percutaneous Coronary Intervention revascularization

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Should Patients with Acute Myocardial Infarction Have Complete revascularization at the Time of PCI of the Culprit Vessel?

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Cardiovascular Innovations and Applications 2016年第B5期1卷 363-364页

作者： C.Richard Conti Department of Medicine University of FloridaGainesvilleFL 32610USA

For many years,cardiovascular clinicians have been making the argument that complete revascularization is the way to proceed in patients with any form of ischemic heart disease.I believe that cardiovascular surgeons agree with this approach and try their best to completely revascularize patients at the time of coronary artery bypass graft surgery.At the University of Florida,we,like many others in the world,treat an acute myocardial infarction as an emergency,and,if there is ST segment elevation,the patient is transported immediately to the cardiac catheterization laboratory from the emergency department,for recanalization of the culprit artery.

关键词： complete revascularization

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Minireview of the clinical efficacy of platelet-rich plasma, platelet-rich fibrin and blood-clot revascularization for the regeneration of immature permanent teeth

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World Journal of Stomatology 2018年第1期6卷 1-5页

作者： Peter E Murray Department of Endodontics College of Dental Medicine Nova Southeastern University

The aim of this mini-review was to investigate and compare the clinical efficacy of platelet-rich plasma(PRP) and platelet-rich fibrin(PRF), vs blood clot revascularization(BCR) for the regeneration of immature permanent teeth. The clinical efficacy of PRP, PRF, and BCR to regenerate 90 immature permanent teeth after one year, were compared for their ability to accomplish apical closure, a periapical lesion healing response, root lengthening, and dentinal wall thickening. The 90 cases were published in three different articles. The mean success rate for apical closure after one year was: PRP(89.2%) PRF(80%), and BCR(75.6%). The mean success rate for root lengthening after one year was: BCR(88.9%), PRP(68.2%), and PRF(65%). The periapical lesion healing response was 100% for BCR and 100% for PRP. Dentinal wall thickening was 100% for BCR, and 100% for PRP. All the PRP, PRF, and BCR treatments appeared to be effective. The published clinical results for PRP, PRF, and BCR indicate that these treatments are effective for the regeneration of immature permanent teeth.

关键词： Saving immature teeth Regenerative endodontics Dental pulp revascularization Apical closure

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Peripheral interventions and antiplatelet therapy: Role in current practice

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World Journal of Cardiology 2017年第7期9卷 583-593页

作者： Pahul Singh Yenal Harper Carrie S Oliphant Mohamed Morsy Michelle Skelton Raza Askari Rami N Khouzam Department of Medicine Division of Cardiovascular DiseasesUniversity of Tennessee Health Science Center Methodist University Hospital Department of Clinical Pharmacy University of Tennessee College of Pharmacy Department of Biology Emory University

Peripheral arterial disease(PAD) is a common disorder associated with a high risk of cardiovascular mortality and continues to be under-recognized. The major risk factors for PAD are similar to those for coronary and cerebrovascular disease. Management includes exercise program, pharmacologic therapy and revascularization including endovascular and surgical approach. The optimal revascularization strategy, endovascular or surgical intervention, is often debated due to the paucity of head to head randomized controlled studies. Despite significant advances in endovascular interventions resulting in increased utilization over surgical bypass, significant challenges still remain. Platelet activation and aggregation after percutaneous transluminal angioplasty of atherosclerotic arteries are important risk factors for re-occlusion/restenosis and life-threatening thrombosis following endovascular procedures. Antiplatelet agents are commonly prescribed to reduce the risk of myocardial infarction, stroke and death from cardiovascular causes in patients with PAD. Despite an abundance of data demonstrating efficacy of antiplatelet therapy in coronary artery disease and cerebrovascular disease, there is a paucity of clinical information, clinical guidelines and randomized controlled studies in the PAD population. Hence, data on antiplatelet therapy in coronary interventions is frequently extrapolated to peripheral interventions. The aim of this review article is to elucidate the current data on revascularization and the role and duration of antiplatelet and anticoagulant therapy in re-vascularized lower limb PAD patients.

关键词： Peripheral arterial disease Peripheral vascular disease Antiplatelet therapy revascularization

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Evaluation of the ischemic risk in triple-vessel artery patients undergoing stent implantation

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中国循环杂志 2018年第S1期33卷 139-140页

作者： Yanguo Xin Xin Chen Zhiyue Liu Junli Li Department of Cardiology West China HospitalSichuan UniversityChengduSichuanChina Department of Cardiology Fuling Central HospitalChongqingChina

Objective Coronary artery disease(CAD) is a global problem.Every year, there was millions of patients suffered from CAD. With the fast development of coronary revascularization therapy, the mortality has decreased dra... 详细信息

关键词： Coronary artery disease coronary revascularization therapy multi-vessel coronary artery disease

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Impact of gout on in-hospital outcomes of acute coronary syndrome-related hospitalizations and revascularizations: Insights from the national inpatient sample

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World Journal of Cardiology 2019年第5期11卷 137-148页

作者： Rupak Desai Tarang Parekh Hemant Goyal Hee Kong Fong Dipen Zalavadia Nanush Damarlapally Rajkumar Doshi Sejal Savani Gautam Kumar Rajesh Sachdeva Division of Cardiology Atlanta VA Medical Center Decatur GA 30033 United States Division of Cardiology Morehouse School of Medicine Atlanta GA 30310 United States Department of Health Administration and Policy George Mason University Fairfax VA 22030 United States Department of Internal Medicine Macon University School of Medicine Macon GA 31207 United States Department of Internal Medicine University of Missouri-Columbia Columbia MO 65212 United States Department of Internal Medicine The Wright Center for Graduate Medical Education Scranton PA 18503 United States Department of Health Sciences Coleman College of Health Sciences Houston TX 77030 United States Department of Internal Medicine University of Nevada School of Medicine Reno NV 89557 United States Public Health New York University New York NY 10010 United States Division of Cardiology Emory University School of Medicine Atlanta GA 30322 United States

BACKGROUND Previous studies have established a role of gout in predicting risk and prognosis of cardiovascular diseases. However, large-scale data on the impact of gout on inpatient outcomes of acute coronary syndrome (ACS)-related hospitalizations and post-revascularization is inadequate. AIM To evaluate the impact of gout on in-hospital outcomes of ACS hospitalizations, subsequent healthcare burden and predictors of post-revascularization inpatient mortality. METHODS We used the national inpatient sample (2010-2014) to identify the ACS and goutrelated hospitalizations, relevant comorbidities, revascularization and postrevascularization outcomes using the ICD-9 CM codes. A multivariable analysis was performed to evaluate the predictors of post-revascularization in-hospital mortality. RESULTS We identified 3144744 ACS-related hospitalizations, of which 105198 (3.35%) also had gout. The ACS-gout cohort were more often older white males with a higher prevalence of comorbidities. Coronary artery bypass grafting was required more often in the ACS-gout cohort. Post-revascularization complications including cardiac (3.2% vs 2.9%), respiratory (3.5% vs 2.9%), and hemorrhage (3.1% vs 2.7%) were higher whereas all-cause mortality was lower (2.2% vs 3.0%) in the ACSgout cohort (P revascularization (P revascularization inhospital mortality were lower in Hispanics (OR 0.45, CI: 0.31-0.67) and Asians (OR 0.65, CI: 0.45-0.94) as compared to white (P revascularization in-hospital mortality in ACS, it di

关键词： Gout Serum uric acid Acute coronary syndrome Unstable angina Myocardial infarction revascularization Percutaneous coronary intervention Coronary artery bypass grafting In-hospital outcomes

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