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OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity

International Journal of Ophthalmology(English edition) 2024年第2期17卷 289-296页

作者： Hong-Xia Gong Bin Wu Shi-Yong Xie Wei Zhang Song Chen Tianjin Key Lab of Ophthalmology and Visual Science Department of Ophthalmology for Integrated Traditional Chinese and Western MedicineTianjin Eye HospitalTianjin 300020China Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300010China Eye Hospital Affiliated to Nankai University Tianjin 300020China

AIM:To observe the retinal and choroidal circulations in patients with non-arteritic permanent central retinal artery occlusion(NA-CRAO)via optical coherence tomography angiography(OCTA)and analyze their correlation with visual ***:Sixty-two eyes with clinically confirmed acute NA-CRAO were included in the study and divided into:A type(mild n=29),B type(moderate n=27)and C type(severe n=6)based on the degree of visual loss,retinal edema,and arterial blood flow delay in fundus fluorescence angiography(FFA).Contralateral healthy eyes were used as the control ***-corrected visual acuity(BCVA),slit lamp microscopy,indirect ophthalmoscopy,fundus color photography,OCTA,and FFA were ***’s correlation analysis was used to determine the correlations between retinal and choroidal vessels and visual ***:There were no statistically significant differences in age,gender,and intraocular pressure among the three types and the control group(P>0.05).vessel density in deep capillary plexus(VD-DCP)significantly decreased(Pdensity in superficial vascular plexus(VD-SVP)significantly decreased(Pretinal flow areas significantly increased in the type A(Pretinal thickness significantly increased in type C group(P<0.05).The VD-SVP at fovea in the type A was significantly lower than both of type B and *** VD-SVP at nasal parafovea in type A and B was significantly lower than type C(P<0.05).The logMAR BCVA of type A was significantly better than that of type B and C groups(P<0.05).Spearman’s correlation analysis showed that the logMAR BCVA was positively correlated with VD-SVP at fovea(r=0.679,P=0.031)and nasal parafovea(r=0.826,P=0.013).CONCLUSION:OCTA is valua

关键词： non-arteritic central retinal artery occlusion fundus fluorescence angiography optical coherence tomography angiography retinal vessel density visual acuity

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Identification of retinal thickness and blood flow in agerelated macular degeneration with reticular pseudodrusen

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International Journal of Ophthalmology(English edition) 2023年第8期16卷 1268-1273页

作者： Yong-Zhao Wei Hao Huang Xiang Zhang Hong-Hua Yu Bao-Yi Liu Yu-Yao Diao Lu Cheng Hao Cheng Department of Ophthalmology the First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120Guangdong ProvinceChina State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510275Guangdong ProvinceChina Guangdong Eye Institute Department of OphthalmologyGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina

AIM:To investigate thickness characteristics and vascular plexuses in retinas with reticular pseudodrusen(RPD)as an early detection strategy for age-related macular degeneration(AMD).METHODS:This retrospective study included 24 subjects(33 eyes)with RPD and 25 heathy control subjects(34 eyes).The superficial capillary plexus(SCP)and the deep capillary plexus(DCP)of the retinal posterior poles were investigated with optical coherence tomography angiography(OCTA).retinal thicknesses and vessel densities were analyzed ***:The general retinal thicknesses of RPD eyes were significantly decreased(95%CI-14.080,-0.655;P=0.032).The vessel densities of DCP in RPD eyes were significantly increased in the global(95%CI 1.067,7.312;P=0.027),parafoveal(95%CI 0.417,5.241;P=0.022),and perifoveal(95%CI 0.181,6.842;P=0.039)***,the vessel densities of the SCP were rarely increased in the eyes with ***:The thinning of retinas in the RPD group suggests a reduction in the number of ***,the increased vessel density of the DCP in retinas with RPD indicates a greater demand for blood supply,possibly due to the hypoxia induced RPD compensation caused by RPD in the outer *** study highlights the pathological risks associated with RPD and emphasizes the importance of early intervention to retard the progression of AMD.

关键词： reticular pseudodrusen age-related macular degeneration retinal thickness retinal vessel density optical coherence tomography angiography

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Structural measurements and vessel density of spectraldomain optic coherence tomography in early,moderate,and severe primary angle-closure glaucoma

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1100-1109页

作者： Wei Jiang Nan Jiang Gui-Bo Liu Jing Lin Cui Li Gui-Qiu Zhao Department of Ophthalmology the Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina

AIM:To compare the macular ganglion cell-inner plexiform layer(GCIPL)thickness,retinal nerve fiber layer(RNFL)thickness,optic nerve head(ONH)parameters,and retinal vessel density(VD)measured by spectral-domain optical coherence tomography(SD-OCT)and analyze the correlations between them in the early,moderate,severe primary angle-closure glaucoma(PACG)and normal ***:Totally 70 PACG eyes and 20 normal eyes were recruited for this retrospective *** eyes were further separated into early,moderate,or severe PACG eyes using the Enhanced Glaucoma Staging System(GSS2).The GCIPL thickness,RNFL thickness,ONH parameters,and retinal VD were measured by SD-OCT,differences among the groups and correlations within the same group were ***:The inferior and superotemporal sectors of the GCIPL thickness,rim area of ONH,average and inferior sector of the retinal VD were significantly reduced(all Pretinal VD were decreasing as well as C/D and cup volume increasing than other three groups(all Pretinal VD and GCIPL thickness(except superonasal and inferonasal sectors,r=0.573 to 0.641,all Pretinal VD and superior sectors of RNFL thickness(r=0.650,P=0.022),and temporal sectors of RNFL thickness(r=0.740,P=0.006).In the severe PACG eyes,neither GCIPL nor RNFL thickness was associated with retinal ***:The ONH damage and retinal VD loss appears earlier than RNFL thickness loss in PACG *** the PACG disease progressed from the earl

关键词： optic coherence tomography primary angle-closure glaucoma ganglion cell-inner plexiform layer retinal nerve fiber layer optic nerve head retinal vessel density

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