检索结果-南通市图书馆

World Journal of Clinical Cases 2023年第9期11卷 1903-1917页

作者： Yu-Hong Xie Ye-Min Zhang Fan-Fan Fan Xi-Yan Song Lei Liu Psychology College of Teacher Education Center of Group Behavior and Social Psychological ServiceNingbo UniversityNingbo 315211Zhejiang ProvinceChina

Depression is a psychological disorder that affects the general public worldwide.It is particularly important to make an objective and accurate diagnosis of depression,and the measurement methods of brain activity have gradually received increasing attention.resting electroencephalogram(EEG)alpha asymmetry in patients with depression shows changes in activation of the alpha frequency band of the left and right frontal cortices.In this paper,we review the findings of the relationship between frontal EEG alpha asymmetry in the resting state and depression.Based on worldwide studies,we found the following:(1)Compared with individuals without depression,those with depression showed greater right frontal EEG alpha asymmetry in the resting state.However,the pattern of frontal EEG alpha asymmetry in the resting state in depressive individuals seemed to disappear with age;(2)Compared with individuals without maternal depression,those with maternal depression showed greater right frontal EEG alpha asymmetry in the resting state,which indicated that genetic or experience-based influences have an impact on frontal EEG alpha asymmetry at rest;and(3)Frontal EEG alpha asymmetry in the resting state was stable,and little or no change occurred after antidepressant treatment.Finally,we concluded that the contrasting results may be due to differences in methodology,clinical characteristics,and participant characteristics.

关键词： Depression Frontal electroencephalogram alpha asymmetry Frontal asymmetry resting state Neurological indicator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第9期14卷 1544-1555页

作者： Laia Farras-Permanyer Nuria Mancho-Fora Marc Montala-Flaquer David Bartres-Faz Lidia Vaque-Alcazar Maribel Pero-Cebollero Joan Guardia-Olmos Quantitative Psychology Section Faculty of PsychologyUniversity of BarcelonaBarcelonaSpain Department of Medicine Faculty of Medicine and Healthy SciencesUniversity of BarcelonaBarcelonaSpain Institute of Neuroscience UB Institute of Complex SystemsUniversity of BarcelonaBarcelonaSpain Institut d’Investigacions Biomediques August Pi i Sunyer BarcelonaSpain

Age-related changes in the brain connectivity of healthy older adults have been widely studied in recent years,with some differences in the obtained results.Most of these studies showed decreases in general functional connectivity,but they also found increases in some particular regions and areas.Frequently,these studies compared young individuals with older subjects,but few studies compared different age groups only in older populations.The purpose of this study is to analyze whole-brain functional connectivity in healthy older adult groups and its network characteristics through functional segregation.A total of 114 individuals,48 to 89 years old,were scanned using resting-state functional magnetic resonance imaging in a resting state paradigm and were divided into six different age groups(<60,60–64,65–69,70–74,75–79,≥80 years old).A partial correlation analysis,a pooled correlation analysis and a study of 3-cycle regions with prominent connectivity were conducted.Our results showed progressive diminution in the functional connectivity among different age groups and this was particularly pronounced between 75 and 79 years old.The oldest group(≥80 years old)showed a slight increase in functional connectivity compared to the other groups.This occurred possibly because of compensatory mechanism in brain functioning.This study provides information on the brain functional characteristics of every age group,with more specific information on the functional progressive decline,and supplies methodological tools to study functional connectivity characteristics.Approval for the study was obtained from the ethics committee of the Comision de Bioetica de la Universidad de Barcelona(approval No.PSI2012-38257)on June 5,2012,and from the ethics committee of the Barcelona’s Hospital Clinic(approval No.2009-5306 and 2011-6604)on October 22,2009 and April 7,2011 respectively.

关键词： brain connectivity resting state default mode network aging healthy functional connectivity resting state network age groups

Amplitude of Low-frequency Oscillations in Parkinson＇s Disease： A 2-year Longitudinal resting-state Functional Magnetic Resonance Imaging Study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第5期128卷 593-601页

作者： Xiao-Fei Hu Jiu-Quan Zhang Xiao-Mei Jiang Chao-Yang Zhou Lu-Qing Wei Xun-Tao Yin Jing Li Yan-Ling Zhang Jian Wang Department of Radiology Southwest Hospital Third Military Medical University Chongqing 400038 China Department of Centre for Disease Prevention and Control Chengdu Military Region Chengdu Sichuan 610021 China Department of Neurology Southwest Hospital Third Military Medical University Chongqing 400038 China

Background：Neuroimaging studies have found that functional changes exist in patients with Parkinson＇s disease （PD）.However,the majority of functional magnetic resonance imaging （fMRI） studies in patients with PD are task-related and cross-sectional.This study investigated the functional changes observed in patients with PD,at both baseline and after 2 years,using resting-state fMRI.It further investigated the relationship between whole-brain spontaneous neural activity of patients with PD and their clinical characteristics.Methods：Seventeen patients with PD underwent an MRI procedure at both baseline and after 2 years using resting-state fMRI that was derived from the same 3T MRI.In addition,20 age-and sex-matched,healthy controls were examined using resting-state fMRI.The fractional amplitude of low-frequency fluctuation （fALFF） approach was used to analyze the fMRI data.Nonlinear registration was used to model within-subject changes over the scanning interval,as well as changes between the patients with PD and the healthy controls.A correlative analysis between the fALFF values and clinical characteristics was performed in the regions showing fALFF differences.Results：Compared to the control subjects,the patients with PD showed increased fALFF values in the left inferior temporal gyrus,right inferior parietal lobule （IPL） and right middle frontal gyrus.Compared to the baseline in the 2 years follow-up,the patients with PD presented with increased fALFF values in the right middle temporal gyrus and right middle occipital gyrus while also having decreased fALFF values in the right cerebellum,right thalamus,right striatum,left superior parietal lobule,left IPL,left precentral gyrus,and left postcentral gyrus （P 〈 0.01,after correction with AlphaSim）.In addition,the fALFF values in the right cerebellum were positively correlated with the Unified PD Rating Scale （UPDRS） motor scores （r =0.5 l,P 〈 0.05,uncorrected） and the change in the UPDRS motor score （r =0.61,P 〈 0.05,uncorrected）.Conclusions：The baseline and lon

关键词： Functional Magnetic Resonance Imaging Longitudinal Parkinson＇s Disease resting state

Increased regional homogeneity in internet addiction disorder： a resting state functional magnetic resonance imaging study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2010年第14期123卷 1904-1908页

作者： LIU Jun GAO Xue-ping Isoken Osunde LI Xin ZHOU Shun-ke ZHENG Hui-rong LI Ling-jiang Institute of Mental-Health Department of Radiology the Second Xiangya Hosipital Central South University Changsha Hunan 410011 China Wayne state University School of Medicine Detroit MI 48202 USA

Background Internet addition disorder （lAD） is currently becoming a serious mental health problem among Chinese adolescents. The pathogenesis of lAD, however, remains unclear. The purpose of this study applied regional homogeneity （ReHo） method to analyze encephalic functional characteristic of lAD college students under resting state. Methods Functional magnetic resonanc image （fMRI） was performed in 19 lAD college students and 19 controls under resting state. ReHo method was used to analyze the differences between the average ReHo in two groups. Results The following increased ReHo brain regions were found in lAD group compared with control group： cerebellum, brainstem, right cingulate gyrus, bilateral parahippocampus, right frontal lobe （rectal gyrus, inferior frontal gyrus and middle frontal gyrus）, left superior frontal gyrus, left precuneus, right postcentral gyrus, right middle occipital gyrus, right inferior temporal gyrus, left superior temporal gyrus and middle temporal gyrus. The decreased ReHo brain regions were not found in the lAD group compared with the control group. Conclusions There are abnormalities in regional homogeneity in lAD college students compared with the controls and enhancement of synchronization in most encephalic regions can be found. The results reflect the functional change of brain in lAD college students. The connections between the enhancement of synchronization among cerebellum, brainstem, limbic lobe, frontal lobe and apical lobe may be relative to reward pathways.

关键词： internet addiction disorder resting state regional homogeneity functional magnetic resonance image

Abnormal intra-network architecture in extra-striate cortices in amblyopia: a resting state fMRI study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Eye and Vision 2019年第1期6卷 156-163页

作者： Zhuo Lu Yufeng Huang Qilin Lu Lixia Feng Benedictor Alexander Nguchu Yanming Wang Huijuan Wang Geng Li Yifeng Zhou Bensheng Qiu Jiawei Zhou Xiaoxiao Wang Center for Biomedical Engineering University of Science and Technology of ChinaHefeiAnhui 230027People’s Republic of China Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Science University of Science and Technology of ChinaHefeiAnhui 230027People’s Republic of China CAS Key Laboratory of Brain Function and Diseases and School of Life Sciences University of Science and Technology of ChinaHefeiAnhui 230027People’s Republic of China Shenyang Aerospace University ShenyangLiaoning 110136People’s Republic of China Department of Ophthalmology First Affiliated Hospital of Anhui Medical UniversityHefeiAnhuiPeople’s Republic of China Asia Pediatric Ophthalmologist Association Rm 2006CC Wu Bldg.302-308 Hennessy Rd.WanchaiHong KongPeople’s Republic of China School of Ophthalmology and Optometry and Eye hospital Wenzhou Medical UniversityWenzhouZhejiang 325003People’s Republic of China

Background:Amblyopia(lazy eye)is one of the most common causes of monocular visual impairment.Intensive investigation has shown that amblyopes suffer from a range of deficits not only in the primary visual cortex but also the extra-striate visual cortex.However,amblyopic brain processing deficits in large-scale information networks especially in the visual network remain unclear.Methods:Through resting state functional magnetic resonance imaging(rs-fMRI),we studied the functional connectivity and efficiency of the brain visual processing networks in 18 anisometropic amblyopic patients and 18 healthy controls(HCs).Results:We found a loss of functional correlation within the higher visual network(HVN)and the visuospatial network(VSN)in amblyopes.Additionally,compared with HCs,amblyopic patients exhibited disruptions in local efficiency in the V3v(third visual cortex,ventral part)and V4(fourth visual cortex)of the HVN,as well as in the PFt,hIP3(human intraparietal area 3),and BA7p(Brodmann area 7 posterior)of the VSN.No significant alterations were found in the primary visual network(PVN).Conclusion:Our results indicate that amblyopia results in an intrinsic decrease of both network functional correlations and local efficiencies in the extra-striate visual networks.

关键词： Amblyopia fMRI resting state Extra-striate cortices Visuospatial network Graph analysis

Decreased regional homogeneity in major depression as revealed by resting-state functional magnetic resonance imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2011年第3期124卷 369-373页

作者： PENG Dai-hui JIANG Kai-da FANG Yi-ru XU Yi-feng SHEN Ting LONG Xiang-yu LIU Jun ZANG Yu-feng Division of Mood Disorder Shanghai Mental Health Center Medical School of ColleagueShanghai Jiao Tong University Shanghai 200030 China Medical Center of Clinic Department Shanghai Mental Health Center Medical School of ColleagueShanghai Jiao Tong University Shanghai 200030 China state Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal University Beijing 100875 China Department of Medical Imaging Shanghai Pu Tuo People's Hospital Shanghai 200060 China

Backgroud Functional imaging studies indicate abnormal activities in cortico-limbic network in depression during either task or resting state. The present work was to explore the abnormal spontaneous activity shown with regional homogeneity （ReHo） in depression by resting-state functional magnetic resonance imaging （fMRI）.Methods Using fMRI, the differences of regional brain activity were measured in resting state in depressed vs. healthy participants. Sixteen participants firstly diagnosed with major depressive disorder and 16 controls were scanned during resting state. A novel method based on ReHo was used to detect spontaneous hemodynamic responses across the whole brain.Results ReHo in the left thalamus, left temporal lobe, left cerebellar posterior lobe, and the bilateral occipital lobe was found to be significantly decreased in depression compared to healthy controls in resting state of depression.Conclusions Abnormal spontaneous activity exists in the left thalamus, left temporal lobe, left cerebellar posterior lobe,and the bilateral occipital lobe. And the ReHo may be a potential reference in understanding the distinct brain activity in resting state of depression.

关键词： depression first episode functional magnetic resonance imaging resting state regional homogeneity

Abnormal resting-state functional network centrality in patients with high myopia： evidence from a voxel-wise degree centrality analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2018年第11期11卷 1814-1820页

作者： Yu-Xiang Hu Jun-Rong He Bo Yang Xin Huang Yu-Ping Li Fu-Qing Zhou Xiao-Xuan Xu Yu-Lin Zhong Jun Wang Xiao-Rong Wu Department of Ophthalmology the First Affiliated Hospitalof Nanchang University Nanchang 330006 Jiangxi ProvinceChina Department of Quality Management Office the Affiliated Ganzhou Hospital of Nanchang University Ganzhou 341000Jiangxi Province China Department of Ophthalmology Xinjiang People's HospitalUrumqi 830000 Xinjiang Uygur Autonomous Region China Department of Ophthalmology Dongxiang People's HospitalFuzhou 344000 Jiangxi Province China Department of Radiology the First Affiliated Hospital of Nanchang University Jiangxi Province Medical Imaging Research Institute Nanchang 330006 Jiangxi Province China Second Department of Respiratory Disease Jiangxi Provincial People's Hospital Nanchang 330006 Jiangxi Province China

AIM： To investigate the functional networks underlying the brain-activity changes of patients with high myopia using the voxel-wise degree centrality（DC） method.METHODS： In total, 38 patients with high myopia（HM）（17 males and 21 females）, whose binocular refractive diopter were-6.00 to-7.00 D, and 38 healthy controls（17 males and 21 females）, closely matched in age, sex, and education levels, participated in the study. Spontaneous brain activities were evaluated using the voxel-wise DC method. The receiver operating characteristic curve was measured to distinguish patients with HM from healthy controls. Correlation analysis was used to explore the relationship between the observed mean DC values of the different brain areas and the behavioral performance.RESULTS： Compared with healthy controls, HM patients had significantly decreased DC values in the right inferior frontal gyrus/insula, right middle frontal gyrus, and right supramarginal/inferior parietal lobule（P〈0.05）. In contrast, HM patients had significantly increased DC values in the right cerebellum posterior lobe, left precentral gyrus/postcentral gyrus, and right middle cingulate gyrus（P〈0.05）. However, no relationship was found between the observed mean DC values of the different brain areas and the behavioral performance（P〉0.05）.CONCLUSION： HM is associated with abnormalities in many brain regions, which may indicate the neural mechanisms of HM. The altered DC values may be used as a useful biomarker for the brain activity changes in HM patients.

关键词： high myopia degree centrality functional magnetic resonance imaging resting state

Reduction in interhemispheric functional connectivity in the dorsal visual pathway in unilateral acute open globe injury patients: a resting-state fMRI study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2018年第6期11卷 1056-1060页

作者： Lei Ye Ran Wei Xin Huang Wen-Qing Shi Qi-Chen Yang Qing Yuan Pei-Wen Zhu Nan Jiang Biao Li Qiong Zhou Fu-Qing Zhou Yi Shao Department of Ophthalmology the First Affiliated Hospital of Nanchang University Eye Center Renmin Hospital of Wuhan University Wuhan University Eye Institute of Xiamen University Fujian Provincial Key Laboratory of Ophthalmology and Visual Science Department of Radiology the First Affiliated Hospital of Nanchang University

This study investigated the changes in interhemispheric functional connectivity （FC） of the whole brain in open globe injury （OGI） patients, using voxel-mirrored homotopic connectivity （VMHC）, and their relationships with clinical features. Totally, 16 male and 2 female acute OGI patients and 18 sex, age, and education-matched healthy volunteers were enrolled in the study. All subjects were scanned through functional magnetic resonance imaging （fMRI）. Receiver operating characteristic （ROC） curves analyses had been used to identify the VMHC in these brain areas could be used as biomarkers to distinguish OGI and from healthy control （HC）. The mean VMHC values in multiple brain areas and clinical OGI manifestations were evaluated with a Pearson correlation analysis. OGI patients had significantly decreased VMHC in the bilateral calcarine/lingual/cuneus （BA18, 19, 30） and middle occipital gyrus （BA18, 19）. The OGI patients had abnormal interhemispheric FC in the dorsal visual pathway, which may represent the pathophysiological mechanism that underlies acute vision loss after OGI.

关键词： unilateral acute open globe injury voxelmirrored homotopic connectivity resting state functional magnetic resonance imaging

Altered spontaneous brain activity in patients with diabetic optic neuropathy:A resting-state functional magnetic resonance imaging study using regional homogeneity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2021年第3期12卷 278-291页

作者： Gui-Ying Guo Li-Juan Zhang Biao Li Rong-Bin Liang Qian-Min Ge Hui-Ye Shu Qiu-Yu Li Yi-Cong Pan Chong-Gang Pei Yi Shao Department of Ophthalmology The First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND Diabetes is a common chronic disease.Given the increasing incidence of diabetes,more individuals are affected by diabetic optic neuropathy(DON),which results in decreased vision.Whether DON leads to abnormalities of other visual systems,including the eye,the visual cortex,and other brain regions,remains unknown.AIM To investigate the local characteristics of spontaneous brain activity using regional homogeneity(ReHo)in patients with DON.METHODS We matched 22 patients with DON with 22 healthy controls(HCs).All subjects underwent resting-state functional magnetic resonance imaging.The ReHo technique was used to record spontaneous changes in brain activity.Receiver operating characteristic(ROC)curves were applied to differentiate between ReHo values for patients with DON and HCs.We also assessed the correlation between Hospital Anxiety and Depression Scale scores and ReHo values in DON patients using Pearson correlation analysis.RESULTS ReHo values of the right middle frontal gyrus(RMFG),left anterior cingulate(LAC),and superior frontal gyrus(SFG)/left frontal superior orbital gyrus(LFSO)were significantly lower in DON patients compared to HCs.Among these,the greatest difference was observed in the RMFG.The result of the ROC curves suggest that ReHo values in altered brain regions may help diagnose DON,and the RMFG and LAC ReHo values are more clinically relevant than SFG/LFSO.We also found that anxiety and depression scores of the DON group were extremely negatively correlated with the LAC ReHo values(r=-0.9336,P<0.0001 and r=-0.8453,P<0.0001,respectively).CONCLUSION Three different brain regions show ReHo changes in DON patients,and these changes could serve as diagnostic and/or prognostic biomarkers to further guide the prevention and treatment of DON patients.

关键词： Diabetes Diabetic optic neuropathy Regional homogeneity resting state Functional magnetic resonance imaging Brain activity

A review of resting-state fMRI and its use to examine psychiatric disorders

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Psychoradiology 2021年第1期1卷 42-53页

作者： Edgar Canario Donna Chen Bharat Biswal Department of Biomedical Engineering New Jersey Institute of Technology619 Fenster HallNewarkNJ07102US

resting-state fMRI(rs-fMRI)has emerged as an alternative method to study brain function in human and animal models.In humans,it has been widely used to study psychiatric disorders including schizophrenia,bipolar disorder,autism spectrum disorders,and attention deficit hyperactivity disorders.In this review,rs-fMRI and its advantages over task based fMRI,its currently used analysis methods,and its application in psychiatric disorders using different analysis methods are discussed.Finally,several limitations and challenges of rs-fMRI applications are also discussed.

关键词： fMRI resting state connectivity