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Comparison of Postpyloric Tube Feeding and gastric Tube Feeding in Intensiv e Care Unit Patients:A Meta-Analysis

Comparison of Postpyloric Tube Feeding and Gastric Tube Feed...

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2014浙江省医学会肠外肠内营养学学术年会

作者： Zhongheng Zhang Xiao Xu Jin Ding Hongying Ni

Background and Objective:Enteral feeding is vital in the critical care setting;however,the optimal route of enteral feeding(postpyloric vs gastric feeding)remains *** aimed to systematically review the current evidence to see whether postpyloric feeding could provide additional benefits to intensive care unit(ICU)***:Randomized controlled trials(RCTs)comparing the efficacy and safety of postpyloric feeding vs gastric feeding were included in our systematic *** ratio(OR)was used for binary outcome data and weighted mean difference(WMD)was used for continuous outcome *** effects were pooled using a fixed or random effects model as ***:Seventeen RCTs were included in our *** tube feeding could deliver higher proportions of estimated energy require-ment(WMD,12%;95%confidence interval[CI],5%-18%)and reduce the gastric residual volume(GRV)(WMD,?169.1 mL;95%CI,?291.995 to?46.196 mL).However,the meta-analysis failed to demonstrate any benefits to critically ill patients with postpyloric tube feeding in terms of mortality(OR,1.05;95%CI,0.77-1.44),new-onset pneumonia(OR,0.77;95%CI,0.53-1.13),and aspiration(OR,1.20;95%CI,0.64-2.25).There was no significant publication bias as represented by an Egger’s bias coefficient of 0.21(95%CI,?1.01 to 1.43;P=.7).Conclusion:As compared with gastric feeding,postpyloric feeding is able to deliver higher proportions of the estimated energy requirement and can help reduce the GRV.

关键词： respiratory aspiration pneumonia,aspiration respiratory aspiration of gastric contents nutritional support meta-analysis enteral nutrition

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Comparison of Postpyloric Tube Feeding and gastric Tube Feeding in Intensive Care Unit Patients:A Meta-Analysis

Comparison of Postpyloric Tube Feeding and Gastric Tube Feed...

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2013年浙江省肠外肠内营养学学术年会

作者： Zhongheng Zhang Xiao Xu Jin Ding Hongying Ni Department of Critical Care Medicine Jinhua Municipal Central Hospital Department of Gastroenterology Jinhua Municipal Central Hospital

Background and Objective:Enteral feeding is vital in the critical care setting;however,the optimal route of enteral feeding(postpyloric vs gastric feeding) remains *** aimed to systematically review the current evidence to see whether postpyloric feeding could provide additional benefits to intensive care unit(ICU) patients. Method:Randomized controlled trials(RCTs) comparing the efficacy and safety of postpyloric feeding vs gastric feeding were included in our systematic *** ratio(OR) was used for binary outcome data and weighted mean difference(WMD) was used for continuous outcome *** effects were pooled using a fixed or random effects model as ***:Seventeen RCTs were included in our *** tube feeding could deliver higher proportions of estimated energy requirement(WMD,12%;95%confidence interval[CI],5%-18%) and reduce the gastric residual volume(GRV)(WMD,-169.1 mL;95%CI,-291.995 to-46.196 mL).However,the meta-analysis failed to demonstrate any benefits to critically ill patients with postpyloric tube feeding in terms of mortality(OR,1.05;95%CI,0.77-1.44),new-onset pneumonia(OR,0.77;95%CI,0.53-1.13),and aspiration (OR,1.20;95%CI,0.64-2.25).There was no significant publication bias as represented by an Egger’s bias coefficient of 0.21(95%CI,-1.01 to 1.43;P =.7).Conclusion:As compared with gastric feeding,postpyloric feeding is able to deliver higher proportions of the estimated energy requirement and can help reduce the GRV.

关键词： respiratory aspiration pneumonia,aspiration respiratory aspiration of gastric contents nutritional support meta-analysis enteral nutrition

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