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Tendon stem/progenitor cell ageing: Modulation and rejuvenation

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World Journal of Stem Cells 2019年第9期11卷 677-692页

作者： Guang-Chun Dai Ying-Juan Li Min-Hao Chen Pan-Pan Lu Yun-Feng Rui Department of Orthopaedics Zhongda HospitalSchool of MedicineSoutheast UniversityNanjing210009Jiangsu ProvinceChina Trauma Center Zhongda HospitalSchool of MedicineSoutheast UniversityNanjing 210009Jiangsu ProvinceChina Orthopaedic Trauma Institute Southeast UniversityNanjing 210009Jiangsu ProvinceChina School of Medicine Southeast UniversityNanjing 210009Jiangsu ProvinceChina Department of Geriatrics Zhongda HospitalSchool of MedicineSoutheast UniversityNanjing 210009Jiangsu ProvinceChina China Orthopedic Regenerative Medicine Group Hangzhou 310000Zhejiang ProvinceChina

Tendon ageing is a complicated process caused by multifaceted pathways and ageing plays a critical role in the occurrence and severity of tendon *** role of tendon stem/progenitor cells(TSPCs)in tendon maintenance and regeneration has received increasing attention in recent *** decreased capacity of TSPCs in seniors contributes to impaired tendon functions and raises questions as to what extent these cells either affect,or cause ageing,and whether these age-related cellular alterations are caused by intrinsic factors or the cellular *** this review,recent discoveries concerning the biological characteristics of TSPCs and age-related changes in TSPCs,including the effects of cellular epigenetic alterations and the mechanisms involved in the ageing process,are *** the ageing process,TSPCs ageing might occur as a natural part of the tendon ageing,but could also result from decreased levels of growth factor,hormone deficits and changes in other related ***,we discuss methods that might induce the rejuvenation of TSPC functions that are impaired during ageing,including moderate exercise,cell extracellular matrix condition,growth factors and hormones;these methods aim to rejuvenate the features of youthfulness with the ultimate goal of improving human health during ageing.

关键词： Tendon stem/progenitor cell Ageing Mechanisms Modulation rejuvenation

A STUDY ON RECESSION MECHANISM AND rejuvenation WAYS OF THENORTHEAST OLD INDUSTRIAL BASE

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Chinese Geographical Science 1997年第1期7卷 88-94页

作者：李诚固黄岩君王祁春 Science Institute of City and Environment Northeast Normal University Changchun P. R. China Changchun Institute of Geography the Chinese Academy of Sciences Changchun P. R. China

Using the theory of regional superiority of forming and developing Of the old industrial bases and theory of transfondng industrial structure, the paper analyses the recession characteristics, reasons and mechanism of the northest Old industrial base. On the basis of analysing and using the successful experience of other countries, the authors put forward the pattern, goal and way of transforming the northeast old industrial base, combined with the particular national conditions. The poper wants to make the theory and practice system of forming and developing of the world industrial bases more perfect, and provide some experience to promote the systematic development and speed up the industrialized course in the industrial ha of developing countries.

关键词： northeast old industrial base recession mechanism industrial structure rejuvenation

Preventing aging with stem cell rejuvenation:Feasible or infeasible?

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World Journal of Stem Cells 2017年第1期9卷 1-8页

作者： Kanya Honoki Department of Orthopedic Surgery Nara Medical UniversityKashiharaNara 634-8521Japan

Characterized by dysfunction of tissues, organs, organ systems and the whole organism, aging results fromthe reduced function of effective stem cell populations. Recent advances in aging research have demonstrated that old tissue stem cells can be rejuvenated for the purpose of maintaining the old-organ function by youthful re-calibration of the environment where stem cells reside. Biochemical cues regulating tissue stem cell function include molecular signaling pathways that interact between stem cells themselves and their niches. Historically, plasma fractions have been shown to contain factors capable of controlling age phenotypes; subsequently, signaling pathways involved in the aging process have been identified. Consequently, modulation of signaling pathways such as Notch/Delta, Wnt, transforming growth factor-β, JAK/STAT, mammalian target of rapamycin and p38 mitogen-activated protein kinase has demonstrated potential to rejuvenate stem cell function leading to organismic rejuvenation. Several synthetic agents and natural sources, such as phytochemicals and flavonoids, have been proposed to rejuvenate old stem cells by targeting these pathways. However, several concerns still remain to achieve effective organismic rejuvenation in clinical settings, such as possible carcinogenic actions; thus, further research is still required.

关键词： Aging Stem cell Niche rejuvenation Signaling pathway

10 Cultivars of the rejuvenation Rose Group

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北京林业大学学报 1992年第S2期14卷 102-106页

作者： Ma Yan Chen JunyuDepartment of Landscape Architecture ,Beijing Forestry University

On the basis of six-years’study (1986-1991) in the field of distant crossing, ten rose cultivars-elect of the to be established rejuvenation Rose Group are recommended here for the first time. These cultivars have pe... 详细信息

关键词： rejuvenation Rose Group rose breeding flowering winter-hardiness disease-resistance

Characterisation of Bacteria⁃Based Concrete Crack rejuvenation by Externally Applied Repair

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Journal of Harbin Institute of Technology(New Series) 2020年第4期27卷 20-30页

作者： Jie Yuan Xin Chen Mohamed Alazhari Bo Yang Guorong Zhang School of Transportation Science and Engineering Harbin Institute of TechnologyHarbin 150090China State Key Laboratory of Safety and Health for In-Service Long Span Bridges JSTI GroupNanjing 210019China BRE Centre for Innovative Construction Materials University of BathBath BA27AYUK

Microbiologically⁃induced calcite⁃precipitation(MICP)has been increasingly studied in structural repair including self⁃healing and external *** various MICP pathways,enzymatic urea hydrolysis is suggested to be applied as external repair instead of self⁃*** study comprehensively characterised the enzymatic urea hydrolysis pathway in physical,impermeable,and mechanical rejuvenation of concrete *** visual quality of repaired structures was presented,and the importance of humidity in the remediation of cracks was ***,this study investigated the differences in the effectiveness of repair between premixing bacteria with urea and without any *** premixing,there was a concern that the accelerated reactions would precipitate calcite in the shallow spaces of the cracks and impede deeper ***,the observed results indicated that neither physical nor impermeable rejuvenation of concrete cracks repair would be detrimentally *** results obtained from this study will allow further development in commercialisation since the effectiveness of repair has been confirmed with an improvement in its efficiency.

关键词： concrete crack rejuvenation bacteria repair agent relative humidity impermeability chloride penetration flexural strength

Structural evolution in deformation-induced rejuvenation in metallic glasses: A cavity perspective

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Chinese Physics B 2019年第4期28卷 280-285页

作者：江少钦黄勇李茂枝 Department of Physics Beijing Key Laboratory of Opto-electronic Functional Materials & Micro-nano DevicesRenmin University of China

Classical molecular dynamics simulations have been performed to investigate the structural evolution in deformationinduced rejuvenation in Cu_(80)Zr_(20) metallic glass. Metallic glasses obtained by different cooling rates can be rejuvenated into the glassy state with almost the same potential energy by compressive deformation. The aging effect in different metallic glasses in cooling process can be completely erased by the deformation-induced rejuvenation. The evolution of cavities has been analyzed to understand the structural evolution in rejuvenation. It is found that as metallic glasses are rejuvenated by mechanical deformation, a lot of cavities are created. The lower the potential energy is, the more the cavities are created. The cavities are mainly created in the regions without cavities or with small cavities populated, indicating that the irreversible rearrangements induced by deformation are accompanied by the creation of cavity. This finding elucidates the underlying structural basis for rejuvenation and aging in metallic glasses from the cavity perspective.

关键词： metallic glasses rejuvenation cavity

Fractional Ablative Radio-Frequency Resurfacing in Asian and Caucasian Skin: A Novel Method for Deep Radiofrequency Fractional Skin rejuvenation

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Journal of Cosmetics, Dermatological Sciences and Applications 2012年第3期2卷 144-150页

作者： R. Stephen Mulholland D. H. Ahn Michael Kreindel Malcolm Paul Daeyoung Plastic Surgery Practice Seoul South Korea Department of Surgery Aesthetic and Plastic Institute University of California Irvine California Invasix Ltd. Toronto Canada Private Plastic Surgery Practice Toronto Canada

This paper reports the clinical experience of a multi-center, multiple physician trial with a novel fractional radiofrequency ablative skin resurfacing and rejuvenation device (Fractora, Invasix, Israel) deployed on both Caucasian skin types I - III and Asian skin type IV. Histological study demonstrated deep ablation and collagen restructuring in the papillary and reticular dermis. The Fractora device combines the more “cone shaped” ablation seen with CO2 and Erbium lasers with a deep non-ablative heating pattern, seen with other bipolar RF fractional needle resurfacing devices. Ablation, coagulation zones and healing dynamics are analyzed for different energy settings. Two different treatment protocols are suggested: one for light skin and then one for darker skin with a higher risk of post-inflammatory hypperpigmentation. Treatment results show improvement in skin texture, pores, wrinkles and skin dyschromia.

关键词： Skin Resurfacing Skin rejuvenation Fractional Treatment

Optimised Migrate Virtual Machine rejuvenation

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Journal of Computer and Communications 2015年第8期3卷 33-40页

作者： Sanheji Manel Azizi Ridha Maaloul Alia Institute of Higher Technological Studies of Gabes Gabes Tunisia Institute of Higher Technological Studies of Sousse Sousse Tunisia

Server virtualization is an essential component in virtualized software infrastructure such as cloud computing. Virtual machines are generated through a software called virtual machine monitor (VMM) running on physical servers. The risks of software aging caused by aging-related bugs affect both VM and VMM. As a result, service reliability degrades may generate huge financial losses to companies. This paper presents an analytic model using stochastic reward nets for time-based rejuvenation techniques of VMM and VM. We propose to manipulate the VM behavior while the VMM rejuvenation is according to the load on the system. Using a previous Petri net model of virtualized server, we performed an algorithm in order to optimize rejuvenation technique and achieve high availability. So we perform Migrate-VM rejuvenation or Warm-VM rejuvenation while there are current jobs in the system. Although Migrate-VM rejuvenation is better than Warm-VM rejuvenation in steady state availability, it can’t be always performed as it depends on the capacity of the other host. When the queue is empty and the virtual machine has no current jobs to serve, we propose to combine both VMM rejuvenation and VM rejuvenation. We show that the proposed technique can enhance the availability of VMs.

关键词： Component Availability Data Center rejuvenation Virtual Machine Petri Net

Global facial rejuvenation, new technique

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Plastic and Aesthetic Research 2018年第7期5卷 20-25页

作者： Giuseppe Colombo Vittorio Ruvolo Koru Day Clinic Center Via Paleocopa 5/3Savona 17100Italy

Facial aging is the combination of multiple effects such as sun exposure, tobacco, environmental stress and smog, reflecting the cumulative and dynamic effects of time on the skin, soft tissues and the deep structural components of the face that show an important change structural features of the skin and loss of facial volume. There are many different techniques currently used to perform face lifting, the ultimate goal is to get good results with respect for patient safety. This article describes a new approach to facial rejuvenation combining superficial musculoaponeurotic system (SMAS) plication elements on four vectors, with a blepharoplasty to achieve a lasting improvement in facial aging. The plication of the SMAS on the suture provides three vectors of elevation under the skin in the middle rhytidectomy, linked to the Lorè fascia and to the third platys elevation vector behind the ear. The blepharoplasty technique is often unavoidable in the execution of the global facial rejuvenation. This allows obtaining excellent results both in terms of aesthetic and of a good patient empowerment. This new surgical technique, called 'KORU technique', was used on 31 patients between October 2010 and October 2012, producing lasting results, reducing injuries and respecting anatomical planes. This approach can be safely and easily performed under local anesthesia as an isolated midface procedure, respecting and safeguarding the facial nerve. This type of chiropractic technique can be used by young surgeons.

关键词： Facial aging rejuvenation smas surgical technique anatomical planes midface blepharoplastry