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检索条件"主题词=protein-protein interaction"
117 条 记 录,以下是1-10 订阅
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protein-protein interaction map is a key gateway into liver regeneration
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World Journal of Gastroenterology 2010年 第28期16卷 3491-3498页
作者: Chao Xie Run-Zhi Zhu Yun-Sheng Yuan Hong-Lin He Yan Yu Chao Xie Qiu-Shi Huang Jin Gao Wei Han School of Agriculture and Biology Shanghai Municipality Key Laboratory of Veterinary Biotechnology Shanghai Jiao Tong University Shanghai 200240 China Department of Food Science Cornell University Ithaca NY 14853 United States Laboratory of Regeneromics School of Pharmacy Shanghai Jiao Tong UniversityShanghai 200240 China
Recent studies indicate that the process of liver regeneration involves multiple signaling pathways and a variety of genes,cytokines and growth factors. protein-protein interactions(PPIs)play a role in nearly all even... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
protein-protein interaction Between Domains of PDZ and BAR from PICK1
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Chemical Research in Chinese Universities 2007年 第2期23卷 191-195页
作者: XIAO Hong SHI Ya-wei WANG Li-li YUAN Jing-ming Institute of Biotechnology Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education Shanxi University Taiyuan 030006 P. R. China
Two DNA fragments encoding PDZ domain (21-110 residues) and BAR domain ( 150-360 residues) from PICK1 (1-416 residues) were amplified by PCR and then introduced into vectors, pET-32M and pMAL-e2X respectively to... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Review of multimer proteinprotein interaction complex topology and structure prediction
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Chinese Physics B 2020年 第10期29卷 40-49页
作者: Daiwen Sun Shijie Liu Xinqi Gong Mathematics Intelligence Application Laboratory Institute for Mathematical SciencesRenmin University of ChinaBeijing 100872China Beijing Advanced Innovation Center for Structural Biology Tshinghua UniversityBeijing 100094China
proteinprotein interactions (PPI) are important for many biological processes. Theoretical understanding of the structurally determining factors of interaction sites will help to understand the underlying mechanism ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
CPL:Detecting protein Complexes by Propagating Labels on protein-protein interaction Network
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Journal of Computer Science & Technology 2014年 第6期29卷 1083-1093页
作者: 代启国 郭茂祖 刘晓燕 滕志霞 王春宇 School of Computer Science and Technology Harbin Institute of Technology School of Information and Computer Engineering Northeast Forestry University
proteins usually bind together to form complexes, which play an important role in cellular activities. Many graph clustering methods have been proposed to identify protein complexes by finding dense regions in protein... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancer
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Acta Pharmaceutica Sinica B 2022年 第3期12卷 1390-1405页
作者: Sha-Sha Cheng Yuan-Qing Qu Jia Wu Guan-Jun Yang Hao Liu Wanhe Wang Qi Huang Feng Chen Guodong Li Chun-Yuen Wong Vincent Kam Wai Wong Dik-Lung Ma Chung-Hang Leung Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine University of MacaoMacao 999078China Dr.Neher’s Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao 999078China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Ningbo UniversityKow loon TongHong Kong 999077China Laboratory of Biochemistry and Molecular Biology School of Marine SciencesNingbo UniversityNingbo 315211China Department of Chemistry Hong Kong Baptist UniversityNingbo 315211China Institute of Medical Research Northwestern Polytechnical UniversityXi'an 710072China Department of Chemistry City University of Hong KongHong Kong 999077China Department of Biomedical Sciences Faculty of Health SciencesUniversity of MacaoMacao 999078China
Cyclin-dependent kinase 9(CDK9) activity is correlated with worse outcomes of triplenegative breast cancer(TNBC) patients. The heterodimer between CDK9 with cyclin T1 is essential for maintaining the active state of t... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
An effective system for detecting protein-protein interaction based on in vivo cleavage by PPV NIa protease
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protein & Cell 2012年 第12期3卷 921-928页
作者: Nuoyan zheng Xiahe Huang Bojiao Yin Dan Wang Qi Xie Department of Nephrology the First Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510000China Research Center of Translational Medicine the First Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510000China State Key Laboratory of Plant Genomics National Centre for Plant Gene ResearchInstitute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China Animal Center Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China
Detection of protein-protein interaction can provide valuable information for investigating the biological function of *** current methods that applied in protein-protein interaction,such as co-immunoprecipitation and... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Impact of Stable protein-protein interaction on protein Conformational Space
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Chemical Research in Chinese Universities 2015年 第1期31卷 149-155页
作者: LI Wenzhao MENG Wei TIAN Pu College of Life Science Key Laboratory of Molecular Enzymology and Engineering Ministry of Education Jilin University Changchun 130012 P. R. China
Backbone dihedral angle based clustering approach was applied to investigate the effect of protein complexation on backbone conformational space and the effect on protein dynamics. Three representative enzyme-inhibito... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Different stapling-based peptide drug design:Mimicking α-helix as inhibitors of protein-protein interaction
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Chinese Chemical Letters 2018年 第7期29卷 1088-1092页
作者: Xiang Li Yan Zou Hong-Gang Hu School of Pharmacy Second Military Medical University
Peptide stapling strategy has been proven a promising solution in addressing two major pharmacological hurdles, proteolytic stability and membrane permeability, for small peptides as therapeutics. This stapling peptid... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
CAPPh A Cytoskeleton-Based Localization Assay Reports protein-protein interaction in Living Cells by Fluorescence Microscopy
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Molecular Plant 2017年 第11期10卷 1473-1476页
作者: Sulian Lv Huiying Miao Ming Luo Yinxin Li Qiaomei Wang Yuh-Ru Julie Lee Bo Liu Department of Plant Biology University of California Davis CA 95616 USA Key Laboratory of Plant Molecular Physiology Institute of Botany Chinese Academy of Sciences Beijing China Department of Horticulture Zhejiang University Hangzhou Zhejiang 310058 China Biotechnology Research Center Southwest University Chongqing 400716 China
Dear EditorProbing protein-protein interaction has become a routine practice in the post genomic era. Multiple in vitro or in vivo techniques have been developed to detect or report direct or indirect interactions of ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Geometric and amino acid type determinants for protein-protein interaction interfaces
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Frontiers of Electrical and Electronic Engineering in China 2018年 第2期6卷 163-174页
作者: Yongxiao Yang Wei Wang Yuan Lou Jianxin Yin Xinqi Gong Institute for Mathematical Sciences Renmin University of China Beijing 100872 China School of Statistics Renmin University of China Beijing 100872 China
Background: protein-protein interactions are essential to many biological processes. The binding site information of protein-protein complexes is extremely useful to obtain their structures from biochemical experimen... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论