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Effect of male HBV infection on the outcomes of IVF/ICSI cycles:a retrospective cohort study based on propensity score matching

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Asian Journal of Andrology 2024年第4期26卷 415-420页

作者： Su-Qin Zhu Xiu-Hua Liao Wen-Wen Jiang Yan Sun Hui-Ling Xu Xiao-Jing Chen Bei-Hong Zheng Fujian Provincial Reproductive Medicine Center Fujian Maternity and Child Health HospitalCollege of Clinical Medicine for Obstetrics and Gynecology and PediatricsFujian Medical UniversityFuzhou 350001China Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect Fuzhou 350001China Fujian Maternal-Fetal Clinical Medicine Research Center Fuzhou 350001China.

This study aimed to investigate the effects of male hepatitis B virus(HBV)infection on male fertility,embryonic development,and in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI)*** performed a retrospective cohort study that included 3965 infertile couples who received fresh embryo transfer cycles for the first time at the Fujian Maternity and Child Health Hospital(Fuzhou,China)from January 2018 to January *** couples were categorized based on their HBV infection status into the HBV group(HBV-positive men and HBV-negative women)and the control group(HBV-negative couples).A 1:1 propensity score matching was performed with relatively balanced *** characteristics,semen parameters,laboratory outcomes,clinical outcomes,and obstetric and neonatal outcomes were compared between *** propensity score matching,821 couples were included in each *** groups had similar semen parameters and obstetric and neonatal *** HBV group showed a significantly lower live birth rate than the control group(P<0.05).The HBV group had a significantly higher abortion rate than the control group(P<0.05).The rates of high-quality embryos and blastocyst formation were significantly lower in the HBV group than those in the control group(both P<0.05).In conclusion,in couples who undergo IVF/ICSI,male HBV infection reduces the live birth rate and increases the risk of ***,the incidence of low birth weight in women with IVF/ICSI does not increase with male HBV infection.

关键词： hepatitis B virus in vitro fertilization intracytoplasmic sperm injection live birth rate propensity score matching

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The Effect of Xu’s Influenza Decoction Combined with Oseltamivir on Influenza A:A propensity score matching Study

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Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 1-9页

作者： Tianxi Chen Shuyan Fu Fengyuan Tian Qiushuang Li Hongyu Ling Yijie Lou Jun Tang Hong Zheng Basic Medical School Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Department of Infectious Diseases First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina First School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Center of Clinical Evaluation and Analysis First Affiliated Hospital of Zhejiang Chinese Medicine UniversityHangzhou 31006ZhejiangChina Department of General Practice First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina

Background:The resurgence of seasonal influenza virus circulation has been seen in 2021-2022 after the tempo-rary suppression in *** inhibitors(NAIs)are widely applied in the clinical treatment of influenza A despite several ***:To access the efficacy of Xu’s influenza decoction(XID)in combination therapy with oseltamivir for the treatment of influenza ***:In this retrospective cohort study,the eligible participants were diagnosed with influenza A between June 1,2018,and May 30,2022,in the First Affiliated Hospital of Zhejiang Chinese Medical *** to whether Xu’s influenza decoction was applied,patients were divided into two groups:treated with or without *** score matching(PSM)was used to further adjust the covariates between *** primary outcome was to compare time to defervescence via K-M curves,Breslow tests,and Cox regression *** Cox proportional hazards model,a univariate analysis was performed to obtain preliminary results,while a further multivariate analysis was conducted to study the independent factors that influence *** analysis was conducted according to body temperature and time from onset to *** secondary outcome consisted of routine blood and C-reactive protein(CRP),length of stay,and medical ***:A total of 336 patients with influenza A were enrolled in this study(i.e.,163 patients in the XID+oseltamivir group;173 patients in the oseltamivir group).After 1:1 matching via PSM,230 patients meeting the criteria were included in the analysis,with 115 in each *** XID+oseltamivir group had shorter time to defervescence(36 h vs 44 h,P=0.011),shorter length of stay(3 days vs 4 days,P=0.018),and higher defervescence possibility(HR=1.384,95%CI:1.054-1.818).Subgroup analysis indicated that for patients during non-window period(≥48 h)with medium-grade fever(38.1℃-39℃),the XID+oseltamivir combination therapy reduced time to defervescence

关键词： Influenza A Xu’s influenza decoction Oseltamivir Time to defervescence,Cox regression propensity score matching Cohort study

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Can propensity score matching replace randomized controlled trials?

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World Journal of Methodology 2024年第1期14卷 58-70页

作者： Matthias Yi Quan Liau En Qi Toh Shamir Muhamed Surya Varma Selvakumar Vishalkumar Girishchandra Shelat Lee Kong Chian School of Medicine Nanyang Technological UniversitySingapore 308232Singapore Department of General Surgery Tan Tock Seng HospitalSingapore 308433Singapore Surgical Science Training Centre Tan Tock Seng HospitalSingapore 308433Singapore

Randomized controlled trials(RCTs)have long been recognized as the gold standard for establishing causal relationships in clinical *** that,various limitations of RCTs prevent its widespread implementation,ranging from the ethicality of withholding potentially-lifesaving treatment from a group to relatively poor external validity due to stringent inclusion criteria,amongst ***,with the introduction of propensity score matching(PSM)as a retrospective statistical tool,new frontiers in establishing causation in clinical research were opened *** predicts treatment effects using observational data from existing sources such as registries or electronic health records,to create a matched sample of participants who received or did not receive the intervention based on their propensity scores,which takes into account characteristics such as age,gender and *** its retrospective nature and its use of observational data from existing sources,PSM circumvents the aforementioned ethical issues faced by *** of RCTs exclude elderly,pregnant women and young children;thus,evidence of therapy efficacy is rarely proven by robust clinical research for this *** the other hand,by matching study patient characteristics to that of the population of interest,including the elderly,pregnant women and young children,PSM allows for generalization of results to the wider population and hence greatly increases the external *** of replacing RCTs with PSM,the synergistic integration of PSM into RCTs stands to provide better research outcomes with both methods complementing each *** example,in an RCT investigating the impact of mannitol on outcomes among participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial,the baseline characteristics of comorbidities and current medications between treatment and control arms were significantly different despite the randomization ***,PS

关键词： propensity score matching Randomized controlled trials Randomization Clinical practice Validity Ethics

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Routine nasogastric tube placement in patients with small esophageal perforation after endoscopic foreign body removal may be unnecessary:a propensity score matching analysis

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Gastroenterology Report 2023年第1期11卷 433-438页

作者： Foqiang Liao Qinyu Yang Zhenyi Zhan Zhenhua Zhu Xiaolin Pan Chong Wang Bimin Li Yin Zhu Youxiang Chen Xu Shu Department of Gastroenterology Digestive Disease HospitalThe First Affiliated Hospital of Nanchang UniversityNanchangJiangxiP.R.China Jiangxi Clinical Research Center for Gastroenterology The First Affiliated Hospital of Nanchang UniversityNanchangJiangxiP.R.China

Background:Nasogastric tube(NGT)placement is part of the post-operative management of upper gastrointestinal perforation,but its routine use in esophageal perforation(EP)caused by foreign bodies remains *** purpose of this research was to investigate the necessity for routine NGT placement in patients with EP after endoscopic foreign body ***:A total of 323 patients diagnosed with EP caused by foreign bodies at the First Affiliated Hospital of Nanchang University between January 2012 and December 2021 were included in this retrospective *** were divided into the NGT group and the non-NGT group according to whether or not NGT placement was *** perforation healing rate,post-operative adverse events,hospital stay,and death rate were analysed using a 1:1 propensity score matching ***:Before matching,there were 263 patients in the NGT group and 60 patients in the non-NGT *** were significant differences in the time to treatment,infection,albumin,and types of endoscopy between the two groups,while the length of hospital stay in the NGT group was significantly longer than that in the non-NGT *** 1:1 propensity score matching,48 pairs of patients were matched between the two *** perforation healing rate,post-operative adverse events,length of hospital stay,and death rate did not show significant differences between the two ***:For patients with small EP caused by foreign bodies,routine NGT placement after endoscopic foreign body removal may be unnecessary.

关键词： esophageal perforation foreign body nasogastric tube placement propensity score matching

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Evaluation of early liquid drinking after radical gastrectomy in gastric cancer:a Chinese multicenter propensity score matching analysis

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Gastroenterology Report 2023年第1期11卷 331-339页

作者： Yue Zhang Kaixiong Tao Jinlong Yu Chao Chen Quan Zheng Sanlin Lei Xiaogang Zhong Lixin Liu Wei Wang Qiang Wang En Li Yuwen Luo Guanrong Zhang Xingyu Feng Yong Li Junjiang Wang Department of Gastrointestinal Surgery Department of General SurgeryGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhouGuangdongP.R.China Shantou University Medical College ShantouGuangdongP.R.China Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiP.R.China Department of General Surgery Zhujiang Hospital of Southern Medical UniversityGuangzhouGuangdongP.R.China Department of Gastrointestinal Surgery Huizhou Municipal Central HospitalHuizhouGuangdongP.R.China Department of Gastrointestinal Surgery Guangdong Second Provincial General HospitalGuangzhouGuangdongP.R.China Department of Gastrointestinal Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunanP.R.China Department of Surgical Treatment of Gastrointestinal Hernia and Fistula The People’s Hospital of Guangxi Zhuang Autonomous RegionGuangxi Academy of Medical SciencesNanningGuangxiP.R.China Department of General Surgery The Third Affiliated Hospital of Southern Medical UniversityGuangzhouGuangdongP.R.China Department of Gastrointestinal Surgery The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangdong Provincial Hospital of Traditional Chinese MedicineGuangzhouGuangdongP.R.China Department of Gastrointestinal Surgery Guangzhou First People’s HospitalGuangzhouGuangdongP.R.China Department of Gastrointestinal Surgery Meizhou People’s HospitalMeizhouGuangdongP.R.China lnformation and Statistics Center Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhouGuangdongP.R.China

Background:Enhanced recovery after surgery is used in gastrointestinal *** study aimed to access the effects of early liquid drinking(ELD)on gastrointestinal function recovery in patients with gastric cancer(GC)who underwent radical gastrectomy,as high-quality evidence on the outcomes of ELD after gastrectomy is currently ***:Clinicopathological data of patients with GC from 11 centers were retrospectively *** outcomes were investigated in 555 patients,including 225 who started drinking liquid within 48 h(ELD group)of surgery and 330 who started drinking liquid after flatus resumption(traditional liquid drinking[TLD]group).propensity score matching(PSM)analysis was performed using a match ratio of 1:1 and 201 patients were selected from each group for the *** outcome was time to first passage of *** outcomes included time to first defecation,post-operative hospitalization days,occurrence of short-term post-operative complications,and hospitalization ***:After PSM,baseline characteristics were not significantly different between the two *** time to first flatus(2.7261.08 vs 3.3661.39 days),first defecation(4.3461.85 vs 4.7761.61 days),and post-operative hospital stay(8.2764.02 vs 12.9464.43 days)were shorter in the ELD group than in the TLD group(all P<0.05).The ELD group had lower hospitalization costs than the TLD group([7.8362.44 vs 8.7863.41]104 RMB,P=0.041).No significant differences were observed in the incidence of post-operative ***:Compared with TLD,post-operative ELD could promote rapid recovery of gastrointestinal function and reduce hospitalization costs;moreover,ELD does not increase the risk of post-operative complications.

关键词： gastric cancer early liquid drinking traditional liquid drinking gastrointestinal function propensity score matching

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Endovenous laser treatment vs conventional surgery for great saphenous vein varicosities: A propensity score matching analysis

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World Journal of Clinical Cases 2023年第35期11卷 8291-8299页

作者： Qiang Li Chen Zhang Zhao Yuan Zi-Qi Shao Jian Wang Department of General Surgery The Second Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Varicosis is a common venous condition,which is typically treated ***,selection of the optimal surgical approach can be *** studies comparing endovenous laser treatment(EVLT)and conventional surgery were retrospective and observational in nature and the results may therefore have been influenced by selection bias and the presence of other confounding *** this study,we used propensity score matching to reduce selection bias when comparing EVLT and conventional surgery for the treatment of varicose great saphenous *** We retrospectively reviewed the records of 1063 patients treated for primary varicosis of the great saphenous vein at the Second Affiliated Hospital of Xuzhou Medical University between January 2009 and December *** them,56 patients were excluded owing to additional small saphenous varicose vein involvement,81 owing to recurring varicose veins,83 owing to complicated varicose veins(CEAP clinical classification C5-C6),and 6 owing to perioperative ***,772 patients were enrolled in this *** demographic and clinicopathological data were collected from the medical records of the *** propensity score matching,522 patients(261 who underwent EVLT and 261 who underwent conventional surgery)were randomly matched 1:1 by age,sex,onset time,smoking status,presence of diabetes,family history,stress therapy,C class,and the affected *** Of the 772 patients included in the study,467 underwent EVLT and 305 underwent conventional *** were significant differences in age,onset time,smoking and diabetes status,and family history between the two *** propensity score matching,no significant differences in patients’characteristics remained between the two *** was associated with a shorter operation time and hospital stay than conventional surgery,both before and after propensity score *** were no differences in complications betwe

关键词： Endovenous laser treatment Conventional surgery Great saphenous vein propensity score matching Outcomes Varicosis

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Does gastric stump cancer really differ from primary proximal gastric cancer? A multicentre, propensity score matching-used, retrospective cohort study

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2553-2563页

作者： Shuan-Hu Wang Jing-Cheng Zhang Liang Zhu He Li Kong-Wang Hu Department of the General Surgery The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Department of Surgery Technical University of MunichSchool of MedicineKlinikum rechts der IsarMunich 80-819Germany Department of the General Surgery Anhui Provincial HospitalHefei 230001Anhui ProvinceChina Department of the Emergency Surgery The Second Affiliated Hospital of Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of the General Surgery The First Affiliated Hospital of Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of the General Surgery The Fuyang Affiliated Hospital of Anhui Medical UniversityFuyang 236000Anhui ProvinceChina

BACKGROUND Although the location of proximal cancer of the remnant stomach is the same as that of primary proximal cancer of the stomach,its clinical characteristics and prognosis are still *** To evaluate the clinicopathological features and prognosis factors of gastric stump cancer(GSC)and primary proximal gastric cancer(PGC).METHODS From January,2005 to December,2016,178 patients with GSC and 957 cases with PGC who received surgical treatment were *** in both groups underwent 1:1 propensity score matching analysis,and both clinical and pathological data were systematically collected for statistical *** of RESULTS One hundred and fifty-two pairs were successfully matched after propensity score matching *** the 15 demographic and pathological variables collected,the analysis further revealed that the number of lymph nodes and positive lymph nodes were different prognostic and clinicopathological factors between PGC and *** and multivariate analyses showed that gender,differentiation degree and tumor-node-metastasis stage were independent risk factors for patients with ***,vascular invasion,differentiation degree,depth of infiltration,positive lymph nodes,and tumor-node-metastasis stage were independent risk factors for patients with *** 5-year overall survival and cancer-specific survival of patients with GSC were significantly lower than those in the PGC group,the scores for overall quality of life in the GSC-malignant group were lower than the GSC-benign,and the differences were statistically *** The differences in clinicopathological characteristics between GSC and PGC were clarified,and PGC had a better prognosis than GSC.

关键词： Gastric stump cancer Primary gastric cancer Clinicopathological risk factors Quality of life propensity score matching

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Laparoscopic vs open total gastrectomy for advanced gastric cancer following neoadjuvant therapy:A propensity score matching analysis

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World Journal of Gastrointestinal Surgery 2022年第2期14卷 161-173页

作者： Hai-Tao Hu Fu-Hai Ma Jian-Ping Xiong Yang Li Peng Jin Hao Liu Shuai Ma Wen-Zhe Kang Yan-Tao Tian Department of Pancreatic and Gastric Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021Beijing ProvinceChina

BACKGROUND Laparoscopic total gastrectomy(LTG)has drawn increasing attention over the *** LTG has shown surgical benefits compared to open TG(OTG)in early stage gastric cancer(GC),little is known about the surgical and oncological outcomes of LTG for advanced GC following neoadjuvant therapy(NAT).AIM To compare the long-and short-term outcomes of advanced GC patients who underwent LTG vs OTG following *** Advanced GC patients who underwent TG following NAT between April 2011 and May 2018 at the Cancer Hospital of the Chinese Academy of Medical Sciences were enrolled and stratified into two groups:LTG and *** score matching analysis was performed at a 1:1 ratio to overcome possible *** In total,185 patients were enrolled(LTG:78;OTG:109).Of these,138 were paired after propensity score *** adjustment for propensity score matching,baseline parameters were similar between the two *** to OTG,LTG was associated with a significantly shorter length of hospital stay(P=0.012).The rates of R0 resection,lymph node harvest,and postoperative morbidity did not significantly differ between the two *** survival(OS)outcomes were comparable between the two *** T and N stages were found to be independent risk factors for *** LTG can be a feasible method for advanced GC patients following NAT,as it appears to be associated with better short-and comparable long-term outcomes compared to OTG.

关键词： Gastric cancer Laparoscopic total gastrectomy Open total gastrectomy Neoadjuvant therapy propensity score matching

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Association between Self-Rated Health and Depressive Symptoms in Rural Chinese Adults:A Cohort Study Based on propensity score matching

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International Journal of Mental Health Promotion 2022年第3期24卷 385-398页

作者： Yang Wang Jinlong Lin MJames C.Crabbe Xiao-Guang Yue Institute of Population Research Peking UniversityBeijing100871China Wolfson College University of OxfordOxfordOX26UDUK Institute of Biomedical and Environmental Science&Technology School of Life SciencesFaculty of Creative ArtsTechnologies and ScienceUniversity of BedfordshireUniversity SquareLutonLU13JUUK School of Life Science Shanxi UniversityTaiyuan030006China Department of Computer Science and Engineering School of SciencesEuropean University CyprusNicosiaCyprus

Health status is widely regarded as a correlate of depressive ***,health assessments based on clinical diagnosis in rural areas with poor medical conditions are very ***-rated health(SRH)serves as a simple and convenient evaluation indicator,which may be used as an independent predictor of depressive *** confirm the relationship between SRH and depressive symptoms in rural adults,a longitudinal survey of rural households in China was conducted using the China Family Panel Studies(CFPS)from 2012 to *** score matching and logistic regression analysis were used to explore the *** data cleansing,3,127 pairs(6,254 participants)aged 16 and older followed for 4 years were enrolled,of which the average age was(50.02±14.19)years old,and the proportions of male and female were 48.64%and 51.36%,*** incidence rate of depressive symptoms within 4 years was 30.86%(95%CI:29.24–32.48)in the group with fair or poor SRH,and 21.59%(95%CI:20.14–23.03)in the group with good *** difference between the two groups was statistically significant(χ^(2)=69.51,P<0.001).The results of univariate unconditional logistic regression analysis showed that there was a correlation between SRH and depressive symptoms in rural adults aged 30 and above(OR=1.65,95%CI:1.46–1.85,P<0.001).Thus,a simple and practical assessment tool based on SRH and other indicators should be established for early prevention and intervention in rural primary mental health care.

关键词： rural adults self-rated health depressive symptoms cohort study propensity score matching

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Cholecystectomy is associated with higher risk of recurrence after microwave ablation of hepatocellular carcinoma:a propensity score matching analysis

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Cancer Biology & Medicine 2020年第2期17卷 478-491页

作者： Hongcai Yang Yi Yang Jianping Dou Rui Cui Zhigang Cheng Zhiyu Han Fangyi Liu Xiaoling Yu Xiang Zhou Jie Yu Ping Liang School of Medicine Nankai UniversityTianjin 300071China Department of Interventional Ultrasound Chinese PLA General HospitalBeijing 100853China Department of Interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Objective:To explore the association between cholecystectomy and the prognostic outcomes of patients with hepatocellular carcinoma(H CC)who underwent microwave ablation(MWA).Methods:Patients with HCC(«=921)who underwent MWA were included and divided into cholecystectomy(n=114)and non-cholecystectomy groups(n=807).After propensity score matching(PSM)at a 1:2 ratio,overall survival(OS)and disease-free survival(DFS)rates were analyzed to compare prognostic outcomes between the cholecystectomy(«=114)and non-cholecystectomy groups(n=228).Univariate and multivariate Cox analyses were performed to assess potential risk factors for OS and *** complications were also compared between the ***:After matching,no significant differences between groups were observed in baseline *** 1-,3-,and 5-year OS rates were 96.5%,82.1%,and 67.1%in the cholecystectomy group,and 97.4%,85.2%,and 74.4%in the non-cholecystectomy group(P=0.396);the 1-,3-,and 5-year DFS rates were 58.4%,34.5%,and 26.6%in the cholecystectomy group,and 73.6%,44.7%,and 32.2%in the non-cholecystectomy group(P=0.026),*** intrahepatic distant recurrence rate in the cholecystectomy group was significantly higher than that in the non-cholecystectomy group(P=0.026),and the local tumor recurrence and extrahepatic recurrence rates did not significantly differ between the groups(P=0.609 and P=0.879).Multivariate analysis revealed that cholecystectomy(HR=1.364,95%Cl 1.023-1.819,P=0.035),number of tumors(2 vs.1:HR=2.744,95%Cl 1.925-3.912,P<0.001;3 vs.1:HR=3.411,95%Cl 2.021-5.759,P<0.001),and y-GT levels(HR=1.003,95%Cl 1.000-1.006,P<0.024)were independent risk factors for *** best y-GT level cut-off value for predicting median DFS was 39.6 U/L(area under the curve=0.600,P<0.05).A positive correlation was observed between cholecystectomy and y-GT level(r=0.108,95%Cl-0.001-0.214,P=0.047).Subgroup analysis showed that the DFS rates were significantly higher in the non-cholecystectomy

关键词： Cholecystectomy microwave ablation hepatocellular carcinoma propensity score matching

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