检索结果-南通市图书馆

prognostic Materno-Fetal Types of Arterille Hypertension during Pregnancy at the Maternity of Donka, National Hospital Donka, Chu of Conakry, Guinea

引用

Open Journal of Obstetrics and Gynecology 2019年第5期9卷 722-729页

作者： Boubacar Siddi Diallo Mamadou Sambakeita Ibrahima Sory Balde Oumar Diawara Telly Sy Mohamed Lamine Kaba Yolande Hyjazi Namory Keita University Department of Gynecology-Obstetrics Donka National Hospital Conakry Guinea University Department of Gynecology-Obstetrics Ignace Deen National Hospital Conakry Guinea

Objectives: The objectives of this work were to calculate the frequency of arterial hypertension during pregnancy, describe the epidemiological profile, and identify the most common type of hypertension and establish the maternal and fetal prognosis. Methodology: This was a six-month descriptive prospective study performed in the Obstetrics and Gynecology Department of Donka National Hospital, CHU, Conakry. The study took place from July 1st to December 31st, 2015. Results: The frequency of arterial hypertension during pregnancy was 8.82% in the service. The epidemiological profile was that of a teenager (32.8%), nulliparous (56%), coming from home (69.2%), not having performed CPN (52%), no schooling (68%) and housewives. The primary factor was the risk factor (52.4%). Gestational age greater than 37 was the most concerned (62%). The reasons for consultation are dominated by headache (76%) and vertigo (68%). The main type of hypertension was pre-eclampsia (48%) followed by Transient HTA (28%). The predominant clinical form at admission was pre-eclampsia (47.2%) followed by eclampsia (23%). Eclampsia was the major complication (48%), with 6 deaths, or 2.4%. At the first minute, 35.68% of newborns had an APGAR score of less than 7 and 25.5% had a score of less than 7. Fetal morbidity was dominated by fetal hypotrophy (30.19%) followed by prematurity (23.92%). We recorded 30 cases of MFIU and 7 cases of neonatal death out of 255 births, i.e. 14.50%. Conclusion: The detection of risk factors by a good prenatal follow-up and the regular training of the care providers for an adequate and multidisciplinary care (obstetrician, intensive care nephrologist and pediatrician) of hypertensive pregnant women and their newborns can improve the maternal and fetal prognosis.

关键词： prognostic Arterille Hypertension Pregnancy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

prognostic significance of minimal residual disease detection after first induction treatment in adult acute lymphoblastic leukemia patients treated with autologous stem cell transplantation

引用

China Medical Abstracts(Internal Medicine) 2019年第2期36卷 118-118页

作者：黄走芳 Dept Lymphoma Center Instit HematolBlood Dis HospPUMC & CAMS

Objective To investigate the prognostic significanceof detection of minimal residual disease after first inductiontreatment (MRD1) in adult acute lymphoblastic leukemia(ALL) patients treated with autologous stem celltransplantation (auto-HSCT). Methods The clinical dataof 87 ALL patients who underwent auto-HSCT duringFebruary 2006 to April 2017 with MRD1 detection databy flow cytometry were analyzed retrospectively. The relationshipbetween MRD1 and relapse and survival ofALL patients after auto-HSCT was studied. Results Of87 patients,26 (29. 9%) were MRD1 positive. The proportionof high-risk immunophenotype ( pro-B,pro-T,pre-T,mature T) was significantly higher in MRD1-positivepatients than that in MRD1 negative patients(34. 6% vs 14. 5%,P = 0. 038). There was no significantdifference between positive and negative MRD1 patientsof age,sex,lineage ( T /B),immunophenotype(standard risk /high risk),high white blood cell count(B-ALL > 30 × 109 /L or T-ALL > 100 × 109 /L),highriskchromosome /gene ratio,the time from first completeremission to transplantation and pre-treatment regimen.

关键词： pro prognostic significance autologous stem cell transplantation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical characteristics and prognosis of three rare and poor-prognostic subtypes of primary liver carcinoma

引用

China Medical Abstracts(Internal Medicine) 2014年第2期31卷 110-111页

作者：李智宇 Dept Abdominal Surg Cancer HospCAMS & PUMC

Objective To explore the clinicopathological features and prognostic factors of three rare and poor-prognostic pathological subtypes of primary liver carcinoma,and to improve the clinical diagnosis and surgical treatment.Methods A retrospective analysis of clinicopathological data of 69 patients with rare pathological subtypes of primary liver carcinoma,diagnosed by

关键词： prognostic retrospective prognosis postoperative carcino invasion metastasis organs median hilar

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinicopathological characteristics and prognostic analysis of 92 cases with primary gastrointestinal diffuse large B-cell lymphoma

引用

China Medical Abstracts(Internal Medicine) 2014年第2期31卷 107-108页

作者：冯佳 Dept Hematol 3rd Hosp Peking Univ

Objective To analyze the clinical and pathological features,molecular biological markers and prognosis of primary gastrointestinal diffuse large B-cell lymphoma(DLBCL).Methods A retrospective study was conducted in 92 cases of primary gastrointestinal DLBCL.The data of clinical characteristics,pathological and immunohistochemical features were analyzed.The relationship between different factors at diagnosis and prognosis

关键词： diffuse prognosis retrospective prognostic stomach multivariate histochemical remission intestine median

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The prognostic Importance of EGFR and COX-2 Expression in Cervix Cancer Stages IIb-IVa

引用

Journal of Cancer Therapy 2011年第1期2卷 9-15页

作者： Parvin Adimi Karina Dahl Steffensen Doris Schledermann Eva Rye Rasmussen Anders Jakobsen Department of Oncology Vejle Hospital Institute of Regional Health Services Research University of Southern Denmark Department of Pathology Odense University Hospital

Objectives. Locally advanced cervix cancer represents a therapeutic challenge with a delicate balance between effect and toxicity. Consequently, there is an obvious need for new prognostic parameters with a perspective of a more individualized treatment. The aim of the present study was to evaluate the possible prognostic importance of epidermal growth factor receptor and cyclooxygenase-2 expression in locally advanced cervix cancer. Methods. The study included 91 patients with cervix cancer, FIGO stages IIb-IVa, and were treated with curative intent according to the Nordic Cervix Cancer protocol (NOCECA). The median observation time was 7 years. Epidermal growth factor receptor and cyclooxygenase-2 expression was evaluated by immunohistochemistry using commercially available antibodies. The tumor marker expression was evaluated according to a semi-quantitative scoring system with a positive score when more than 10% of the tumor cells were moderately or strongly stained. Results. Epidermal growth factor receptor and cyclooxygenase-2 over-expression was found in 22% and 18% of the patients, respectively. The survival differed according to epidermal growth factor receptor and cyclooxygenase-2 over-expression as calculated by Kaplan-Meier plots and log-rank test (p = 0.0002 and p = 0.0084 respectively). A multivariate Cox Regression analysis identified each tumor marker as an independent prognostic factor. Conclusion. The results clearly indicate epidermal growth factor receptor and cyclooxygenase-2 hold important prognostic information, markedly appearing with a long-term observation. We found that both parameters were independent prognostic factors, and to further clarify this matter our retrospective analysis should be confirmed in a prospective study with more patients.

关键词： Gynecologic Oncology Cervical Cancer EGFR COX-2 prognostic Marker

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

prognostic Factors for Acute Heart Failure (AHF) in the Cardiology Intensive Care Unit (ICU) of the University Hospital Point G (UH Pt G)

引用

World Journal of Cardiovascular Diseases 2019年第1期9卷 42-50页

作者： Camara Youssouf Ba Hamidou Oumar Sangare Ibrahima Toure Karamba Coulibaly Souleymane Sacko Abdoul Karim Coulibaly Alfousseyni Diallo Nouhoum Sidibe Samba Daou Adama Menta Ichaka Diall Ilo Bella Diallo Boubakar Abdoulaye University Hospital Sidy Bocar Sall Kati Mali University Hospital Gabriel Touré Bamako Mali University Hospital Point G Bamako Mali Disease Fighting Centers Bamako Mali

Background and Aim: The absence of data in our context motivates this study aiming to determine the frequency of AHF at the ICU, assess the in-hospital evolution of the disease and to find out poor prognosis.Material and Methods: It was an observational and descriptive study covering the time from January 1, 2014 to March 30, 2017 involving all inpatient records in ICU. From January 2014 to December 2017, collected data included those on socio-demographic, history of diseases and physical examination, and some labor dataincluding Pro BNP, serum creatinine, blood ionogram,?cardiac enzymes and blood count. Also data electrocardiography, echocardiography and in-hospital evolution were collected. Statistical Analysis:Statistical analysis was performed using SPSS (IBM Inc) version 18. Results: AHF occured in 47.36% with a mean age of 58.74 ± 18.407 and extremes of 17 and 90 years, women representing 53.1% (sex ratio Male:Female = 0.88). Hypertension and diabetes were the predominant cardiovascular risk factors with respectively 67.4% and 18.4%. At admission?44%, 37.7% and 17.9% of patients were respectively hypertensive,?normotensive and hypotensive. The clinical expression was mainly global heart failure with 42.6% followed by left heart failure and right heart failure with respectively 37% and 20.4%. The coronary syndromes (all forms) was the first cause of ICA with 34% of cases followed by pulmonary embolism and hypertension with respectively 25.3% and 24.1%. Mean hospital stay was 5.61 ± 3.527 days (1 to 25 days). Complications were recorded in 18.5% of patients with cardiogenic shock in half of all cases. In multi-variate analysis, only hypotension at admission was shown to be the independent factor of poor prognosis with p = 0.016 and OR = 4.453 (1.322 - 14.996). Conclusion: As a common manifestation heart failure can be rapidly fatal in presence of collapsus or hypotension at admission. These factors should be accurately managed to reduce mortality, which remains high in our context.

关键词： Acute Heart Failure prognostic Factors Cardiology Intensive Care Unit Bamako

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Meta-Analysis of the prognostic and Clinicopathological Significance of circZFR in Human Gastrointestinal Cancers

引用

International Journal of Clinical Medicine 2024年第3期15卷 134-144页

作者： Christian Cedric Bongolo Erick Thokerunga Yu Zhang Jian-Cheng Tu Wuhan Life Origin Biotech Joint Stock Co Ltd. Wuhan China College of Life Sciences and Technology Huazhong Agricultural University Wuhan China Department & Program of Clinical Laboratory Medicine and Center for Gene Diagnosis Zhongnan Hospital of Wuhan University Wuhan China

Background: Studies of gastrointestinal (GIT) cancers have shown that circZFR could be involved in the development and progression of various GIT cancers. However, small sample sizes limit the clinical significance of these studies. Here, a meta-analysis was conducted to ascertain the actual involvement of circZFR in the development and prognosis of GIT cancers. Methods: PubMed, Embase, Web of Science, and the Cochrane Library were searched up to December 31, 2023. Hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to evaluate the association between circZFR expression and overall survival (OS). Publication bias was measured using the funnel plot and Egger’s test. Results: 10 studies having 659 participants were enrolled for meta-analysis. High circZFR expression was associated with poor OS (HR = 1.4, 95% CI: 1.20, 1.70). High circZFR expression also predicted larger tumor size (OR = 4.38, 95% CI 2.65, 7.25), advanced clinical stage (OR = 5.33, 95% CI 3.10, 9.16), and tendency for distant metastasis (OR = 2.89, 95% CI: 1.62, 5.11), but was not related to age, gender, and histological grade. Conclusions: In summary, high circZFR expression was associated with poor OS, larger tumor size, advanced stage cancer and tendency for distant metastasis. These findings suggested that circZFR could be a prognostic marker for GIT cancers.

关键词： CircZFR Gastrointestinal prognostic Significance Meta-Analysis

来源：

维普期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

prognostic study of 229 follicular lymphoma patients treated with rituximab combined with chemotherapy

引用

China Medical Abstracts(Internal Medicine) 2019年第2期36卷 122-122页

作者：王楠 Key Lab Med Genomics Shanghai Instit Hematol Shanghai Ruijin Hosp

Objective To explore the clinical characteristics offollicular lymphoma (FL) in the era of rituximab combinedwith chemotherapy and the prognostic significanceof the follicular lymphoma international prognostic index(FLIPI) ,follicular lymphoma international prognosticindex 2 ( FLIPI2 ) , international prognostic index( IPI) ,revised international prognostic index (R-IPI) ,National Comprehensive Cancer Network internationalprognostic index (NCCN-IPI) among Chinese patients.Methods 229 FL patients who were treated initially withrituximab combined with CHOP-like ( cyclophosphamide,doxorubicin,vincristine and prednisone) chemotherapyfrom November 2008 to April 2018 were analyzedretrospectively and all were scored by the aboveclinical index. Univariate and multivariate survival analysiswere performed on 201 patients who completed thetreatment and were followed regularly. Results In theunivariate survival analysis,age >60 years,hemoglobin prognostic factors for overall survival (OS) and progressionfree survival (PFS).

关键词： PFS prognostic study follicular lymphoma patients chemotherapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

人表皮生长因子受体2在卵巢上皮性癌组织中的过表达及其预后价值

引用

中国实用医刊 2010年第15期37卷 10-11页

作者：梅琳琳岳天孚王雅莉田晓娜河南省郑州市中心医院妇产科 450007 天津医科大学总医院妇产科

目的探讨卵巢上皮性癌组织中人表皮生长因子受体(HER)-2/neu(c-erbB-2)的过表达及其与卵巢上皮性癌患者预后的关系.方法采用免疫组化染色法检测77例卵巢上皮性癌组织中HER-2/neu的过表达,分析其与卵巢上皮性癌临床病理因素和生存时间... 详细信息

目的探讨卵巢上皮性癌组织中人表皮生长因子受体(HER)-2/neu(c-erbB-2)的过表达及其与卵巢上皮性癌患者预后的关系.方法采用免疫组化染色法检测77例卵巢上皮性癌组织中HER-2/neu的过表达,分析其与卵巢上皮性癌临床病理因素和生存时间之间的相关性.结果卵巢上皮性癌组织中HER-2/neu的过表达率为28.6%.单因素分析显示,HER-2/neu过表达阳性患者的中位生存时间(25.7个月)明显短于HER-2/neu过表达阴性者(>34.1个月,P＝0.001).多因素分析显示, HER-2/neu过表达是影响患者预后的独立因素(P＝0.032).结论 HER-2/neu过表达在卵巢上皮性癌的发生和进展中起重要作用,是影响患者预后的独立危险因素.

关键词：人表皮生长因子受体卵巢上皮性癌上皮性癌组织过表达预后价值 significance epithelial ovarian cancer HER-2/neu prognostic factor survival time clinicopathologic features 患者预后 multivariate analysis immunohistochemistry 中位生存时间 c-erbB-2 免疫组化染色法临床病理因素多因素分析独立危险因素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Long-term survival and prognostic implications of Chinese type 2 diabetic patients with coronary artery disease after coronary artery bypass grafting

引用

Health 2009年第3期1卷 139-145页

作者： Ming C Hsiung Tao-Hsin Tung Chung-Yi Chang Yi-Cheng Chuang Kuo-Chen Lee Sung-How Sue Yi-Pen Chou Richard Hsiung Chien-Ming Huang Chang-Chyi Lin Wei-Hsian Yin Mason S Young Jeng Wei Division of Cardiology Department of Medicine Cheng-Hsin General Hospital Department of Medicine Research and Education Cheng-Hsin General Hospital Division of Cardiovascular Surgery Cheng-Hsin General Hospital

This study was conducted to determine the sur-vival rates of type 2 diabetic patients after coro-nary artery bypass grafting (CABG) surgery, and the prognostic factors related to all-cause mor-tality during a 7-year follow-up. The medical re-cords of 816 type 2 diabetic patients who un-derwent primary, isolated CABG surgery during 1997-2003 were studied. The Kaplan-Meier me- thod and Cox regression were used to estimate survival and the independence of prognostic factors associated with all-cause mortality. One hundred and five out of 816 patients expired during the 7-year period. The overall survival rate was 83.5% (95%CI: 78.7-88.3%). Associated prog- nostic factors varied by gender. For males, but not for females, smoking (RR=3.44, 95%CI: 1.01- 11.70), myocardial infarction (RR=4.77, 95% CI: 1.23-18.86), respiratory failure (RR=4.21, 95% CI: 1.48-7.99), cardiogenic shock (RR=12.58, 95% CI: 3.25-20.77), and congestive heart failure (RR= 3.77, 95%CI: 1.10-13.45) were significantly related to all-cause mortality. Older age at sur-gery (RR= 1.15, 95%CI: 1.04-1.27), emergent op-eration (RR= 21.29, 95%CI: 10.03-39.43), pul-monary ede-ma (RR=7.72, 95%CI: 1.89-15.59), and days of ICU stay (RR=1.05, 95%CI: 1.02-1.09) were significant- ly related to all-cause mortality in females only. In conclusion, several gen-der-related differences were noted pertaining to all-cause mortality and its relationship to smok- ing, myocardial infarction, respiratory failure, cardiogenic shock, congestive heart failure, older age at surgery, emergent operation, pul-monary edema, and days of ICU stay.

关键词： Coronary Artery Bypass Grafting Gender Difference prognostic Factors Survival Type 2 Diabetes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：