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Outcomes of additional posterior to ridge diode laser versus conventional laser anterior to ridge in severe stage 3 retinopathy of prematurity-a randomized control trial

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Annals of Eye Science 2017年第1期2卷 255-259页

作者： Amrutha Sindhu Narendran Siddharth Parag K.Shah Venkatapathy Narendran Narendran Kalpana Department of Pediatric Retina&Ocular Oncology Aravind Eye Hospital&Postgraduate Institute of OphthalmologyCoimbatoreTamilnaduIndia

Background:laser photocoagulation restricted to ablation of the avascular retina has been the conventional but not a completely effective treatment strategy in the management of threshold retinopathy of prematurity(ROP).The purpose of this study was to compare the structural outcomes of additional posterior to ridge diode laser compared to conventional diode laser to avascular retina alone in threshold stage III ***:This was a prospective,randomized study involving infants diagnosed with threshold stage III ROP in one or both the *** infants were randomized into control and study *** under the control group underwent conventional laser to avascular retina alone while infants under the study group received additional two rows of laser posterior to the ridge in the vascular *** infants were followed up at 2 weeks,1 month and up to 6 months after the laser ***:During the study period of 1 year,42 eyes of 24 infants were recruited into this study with 21 eyes in each *** mean birth weight was 1,310.48±400.92 g in the test group and 1,341.9±396.2 g in the control *** mean post conceptional age at the time of intervention was 36.43±2.79 weeks in test group and 36.29±2.55 weeks in the control *** 1-month post laser,19 eyes in the study group showed regression of neovascularization laser compared to 18 eyes in the control *** at the end of 3 and 6 months post laser,both groups had showed similar rates regression of neovascularization(19 of 21 eyes in both groups).Five eyes in the study group and six in the control group required additional laser *** eyes in the study group and one eye in the control group developed post laser vitreous ***:posterior to ridge laser treatment for severe stage 3 ROP did not show any additional benefit compared to conventional laser.

关键词： Retinopathy of prematurity(ROP) diode laser posterior to ridge laser

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