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Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats

World Journal of Gastroenterology 2000年第1期6卷 79-83页

作者： Zhu L Yang ZC Li A Cheng DC Institute of Burn Research Southwest HospitalThird Military Medical UniversityChongqing 400038China Critical Care Department Peking Union Medical College Hospital(PUMCH)Chinese Academy of Medical science(CAMS)Beijing 100730China

AIM To study the protective effect of earlyenteral feeding(EEF)on the postburnimpairment of liver function and its *** Wistar rats with 30% of total bodysurface area(TBSA)full-thickness burn *** effects of EEF on the postburnchanges of gastric intramucosal pH,endotoxinlevels in portal vein,water contents of hepatictissue,blood concentrations of tumor necrosisfactor(TNF-α),plasma activities of alanineaminotransferase(ALT)and asparateaminotransferase(AST),as well as the bloodcontents of total(TB)and direct bilirubin(DB),total protein(TP)and albumin(ALB)wereserially determined within 48h *** EEF could significantly improvegastric mucosal acidosis,reduce portal veinendotoxin level and water content of hepatictissue,as well as plasma concentrations of TNF-α at all timepoints after severe burns(Ppostburn elevation of the plasma activities ofALT,AST and the contents of TB,DB wereeffectively prevented,whereas the plasmaconcentrations of TP and ALB were markedlyincreased 24 h and 48 h posturn in EEF groupcompared with that of the burn without EEFgroup(P<0.01).CONCLUSION EEF has significant beneficialeffects on the improvement of hepatic function in rats after severe burn,and is probably relatedwith an increase in splanchnic blood flow,reduction of the absorption of gut-originendotoxin and the consequent release ofinflammatory mediators.

关键词： Subject headings early enteral feeding liver postburn impairments

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postburn dorsal and palmar interdigital commissural contractures: Anatomy and treatment—A new approach

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Advances in Bioscience and Biotechnology 2013年第4期4卷 518-530页

作者： Viktor M. Grishkevich Department of Reconstructive and Plastic Surgery A.V. Vishnevsky Institute of Surgery of the Russian Academy of Medical Sciences Moscow Russia

Background: postburn dorsal and palmar interdigital commissural contracture is one of the most common complications of hand burns which restricts finger motion and presents a serious cosmetic defect. Many techniques and flaps have been suggested, and research continues for more effective techniques as the problem has not been solved. Methods: Anatomy of scar interdigital commissural contractures was studied in 760 operated patients aiming to develop a new, more effective surgical technique. Results: There are two anatomic types of scar commissural contractures: edge and total. Dorsal and palmar commissural contractures are identified as the edge type and are caused by the fold located along interdigital fossa’s edge. In the fold, the lateral sheet is scars, and the medial sheet and adjacent interdigital fossa are healthy skin. Total commissural contracture is characterized by interdigital fossa obliteration and phalanges’ fusion. Scar sheets have a trapeze-shaped surface deficiency (contracture cause), which spreads from the fold’s crest to metacarpophalangeal joints. The surgical technique consists of scar surface deficiency compensation and commissural groove and slant restoration which can be optimally achieved with the trapezoid adipose-cutaneous flap. The best donor site is interdigital fossa. The small skin grafts on the lateral surface of proximal phalanges did not present a cosmetic defect. Conclusion: Dorsal and palmar interdigital commissural contractures are of an edge type and can be successfully reconstructed with trapeze-flap plasty.

关键词： postburn Syndactyly Syndactyly Treatment Hand Burn Complications Trapezoid Flap Trapeze-Flap Plasty

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Pre-expanded bipedicled visor flap:an ideal option for the reconstruction of upper and lower lip defects postburn in Asian males

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Burns & Trauma 2020年第4期8卷 359-367页

作者： Peiru Min Jie Li Beniamino Brunetti Zheming Pu Weijie Su Wenjing Xi Zheng Zhang Rosa Salzillo Shaoqing Feng Yixin Zhang Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghaiChina Department of Plastic and Reconstructive Surgery Campus Bio-Medico University of RomeRomeItaly

Background:Reconstruction of upper and lower lip subunits is a complicated and elusive *** patients affected by defects involving upper and lower lip subunits,a technique able to reconstruct both aesthetic units with matched colour,sufficient contours and similar texture would be *** this study,we present our experience with upper and lower lip reconstruction using the pre-expanded bipedicled visor ***:From January 2014 to January 2017,12 male patients presenting with defects of the upper and lower lip subunits were treated using this surgical *** a period of expansion of the scalp flap of over 6 months,the bipedicled visor flap was raised from both the parietal regions and rotated to resurface the *** and section of the pedicle were then ***:Twelve male patients with postburn scars aged 22 to 48 years(mean:34 years)were successfully treated with no major *** donor site was closed primarily in all *** flap debulking and minor revisions were performed under local anaesthesia between 6 and 12 months ***:The pre-expanded bipedicled visor flap provides an effective and reliable option for upper and lower lip reconstruction with excellent colour and *** is feasible to achieve these results simultaneously from a single donor site by using a pre-expanded bipedicled visor flap.

关键词： postburn Pre-expanded Visor flap Lip defect Reconstruction

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