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Nearly-complete labial adhesions diagnosed with repetitive cystitis in postmenopausal women:A case report

World Journal of Clinical Cases 2022年第35期10卷 12990-12995页

作者： Hyejin Kwon Department of Obstetrics and Gynecology Won Kwang University Sanbon HospitalWon Kwang University School of MedicineGunpo-si15865Gyeonggi-doSouth Korea

BACKGROUND Nearly-complete labial adhesions diagnosed with repetitive cystitis in postmenopausal women:A case report CASE SUMMARY The case of an 83-year-old woman who presented with dysuria,urination disorders,recurrent cystitis,and bacteriuria and was admitted to a private hospital after 1 mo of antibiotic treatment without improvement of her symptoms.Upon examination,labial adhesions were observed with nearly-complete labial fusion with a pinpoint opening.Bacteriuria was detected in urine analysis,and the urine culture test was positive for Escherichia coli.Therefore,a parenteral antibiotic(Fosfomycin)and topical estrogen cream were administered.However,since the adhesion did not separate after 2 wk of treatment,surgical correction was performed.First,adhesiolysis was conducted with a blunt instrument.Then,hysteroscopy and cystoscopy were performed.Hysteroscopic findings showed no abnormalities of the endometrium and endocervix,and the cystoscopic results were also normal.Finally,labiaplasty was completed to prevent adhesion recurrence.One month after the surgery,the discomfort while urinating was eliminated and the adhesion did not recur.CONCLUSION Labial adhesions in postmenopausal women cannot be successfully treated with estrogen creams,and surgical treatment should be considered.

关键词： post menopause Genitalia,female Cystitis Gynecologic Surgical Procedures Atrophy Urinary Retention Case report

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Effect of Ovariectomy on Serum Adiponectin Levels and Visceral Fat in Rats

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2014年第6期34卷 825-829页

作者： Camara Ce 周林远马炎朱琳于东赵要武杨年红 Department of Nutrition and Food Hygiene Hubei Key Laboratory of Food Nutrition and Safety Huazhong University of Science and Technology Department of Nutrition and Food Hygiene Hubei Key Laboratory of Food Nutrition and SafetyHuazhong University of Science and Technology Key Lab of Environment and Health of the Ministry of Education School of Public Health Tongji Medical College Huazhong University of Science and Technology

This study was aimed to examine the effect of ovariectomy on visceral fat, serum adi- ponectin levels and lipid profile. Forty-five female Sprague DawIey rats were divided into three groups （n=15 each）： ovariectomized group （OVX）, ovariectomized plus estrogen-treated group （OVX＋E2）, and sham-operated group （SHAM）. Body weight, abdominal adipose tissues, serum adiponectin and lipid profile were measured and compared among the groups after three-month feeding post-surgery. Signifi- cant increases in body weight and visceral fat were found in ovariectomized rats when compared with sham-operated ones and significant increases were also observed in serum adiponectin, triglyceride and very low density lipoprotein cholesterol levels in ovariectomized rats. Body weight, visceral fat and se- rum adiponectin levels were profoundly reduced in OVX＋E2 group as compared with OVX group. It was concluded that ovarian hormone deficiency induced by ovariectomy leads to significant increases in body weight and visceral fat, along with increased serum adiponectin, triglyceride and very low density lipoprotein cholesterol levels in rats. Attenuation in these changes can be achieved by estrogen supple- mentation.

关键词： ovariectomy estrogen post menopause serum adiponectin visceral fat

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