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苏州大学学报（工科版） 1992年第S2期17卷 27-34页

作者：周晋康

By means of programs GTMPAC based- on generalized triangle method,analysis and synthesis of mechanism design in accordance with absolutely graphicalmethod( absolutely germetrical method) are *** this paper,we make asp... 详细信息

关键词： Ball’s point centering - point Curve and Circling Curve four ISPs Coupler curves based on Balls points

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End points of clinical trials in metastatic castration-resistant prostate cancer:A systematic review

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World Journal of Methodology 2014年第2期4卷 123-132页

作者： Giuseppe Colloca Antonella Venturino Division of Medical Oncology ＂Giovanni Borea＂ HospitalI-18038 SanremoItalyIlaria GovernatoDivision of Medical OncologySanto Spirito Hospital00186 RomaItaly

AIM： To review the defnition and performance of the commonly used end points in trials of systemic thera-pies in metastatic castration-resistant prostate cancer patients. METHODS： A literature search was undertaken on PubMed database to identify studies meeting estab-lished criteria, with the aim of selecting randomized clinical trials and study definition and performance of their end points. The end points were grouped into three categories： overall survival （OS）, time-to-event end points, and response end points. A special analysis was performed for secondary end points of the studies which documented a beneft in OS in the experimental arm. Finally, publishes analyses for surrogacy of the in-cluded end points were also reported. RESULTS： OS, time-to-event and response end points in 31 selected trials were analyzed. OS was the pri-mary end point in 14 trials, and the secondary end point in 17. A time-to-event end point was the primaryend point in 8 studies, and the secondary end point in 22; the most reported time-to-event end points were composite end points, and the events changed among trials. A response end point was the primary end point in 9 studies, in 3 it was prostate-specifc antigen （PSA）-related, in 3 pain-related and in 3 mixed. A response end point was the secondary end point in 19 studies： PSA response and radiologic response were the most frequently used secondary end points in 19 and 11 tri-als, respectively, while pain response was used in 5 ***： A homogeneous defnition of progres-sion in future trials is mandatory. Among response end points, pain-response and PSA-response appear to be the most reliable.

关键词： Metastatic castration-resistant prostate cancer End points Progression-free survival Prostate-specifc antigen Chemotherapy Palliative response

Simple Singular Perturbation Problems with Turning points

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Journal of Applied Mathematics and Physics 2019年第12期7卷 2979-2989页

作者： Na Wang Department of Applied Mathematics Shanghai Institute of Technology Shanghai China

The paper considers the asymptotic solution of two-point boundary value problems εy” + A(x)y’ = 0, 0 ≤ x ≤ 1, when 0 1, A(x) is smooth with isolated zeros, y(0) = 0 and y(1) = 1. By using perturbation method, the limit asymptotic solutions of various cases are obtained. We provide a reliable and direct method for solving similar problems. The limiting solutions are constants in this paper, except in narrow boundary and interior layers of nonuniform convergence. These provide simple examples of boundary layer resonance.

关键词： Singular Perturbations Asymptotic Methods Boundary Value Problems Turning points Boundary and Interior Layers Boundary Layer Resonance

BIFURCATION OF SINGULAR points NEAR A DOUBLE FOLD POINT INZ_2 -SYMMETRIC NONLINEAR EQUATIONS

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Numerical Mathematics A Journal of Chinese Universities(English Series) 1993年第1期2卷 101-115页

作者：吴微吴柏生李荣华 Department of Mathematics Jilin University Changchun 130023PRC

We consider the bifurcation of singular points near a double fold point in Z2 -symmetric nonlinear equations with two parameters,where the linearization has a two dimensional null space spanned by a symmetric null vector and an ami-symmetric null vector. In particular, we show the existence of a turning point path and a pitchfork point path passing ihrough the double fold point and they are the only singular points nearby. Their nondegeneracy is confirmed. A supporting numerical example is also provided. The main tools for our analysis as well as the compulation are some extended systems.

关键词： Double fold points Z2 -symmetry bifurcation of nonlinear equations singular points turning points pitchfork points extended systems.

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Adaptive “Cubature and Sigma points” Kalman Filtering Applied to MEMS IMU/GNSS Data Fusion during Measurement Outlier

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Journal of Sensor Technology 2013年第4期3卷 115-125页

作者： Hamza Benzerrouk Hassen Salhi Alexander Nebylov International Institute for Advanced Aerospace Technologies of Saint-Petersburg State University of Aerospace Instrumentation 67 Bolshaya Morskaya Saint Petersburg Russia SET Laboratory (Systèmes Electriques et Télecommande) of Electronic Department of Saad Dahlab University of Blida Soumaa Algeria

In this paper, adaptive sensor fusion INS/GNSS is proposed to solve specific problem of non linear time variant state space estimation with measurement outliers, different algorithms are used to solve this specific problem generally occurs in intentional and non-intentional interferences caused by other radio navigation sources, or by the GNSS receiver’s deterioration. Non linear approximation techniques such as Extended Kalman filter EKF, Sigma Point Kalman Filters such as UKF and CDKF are computed to estimate the navigation states for UAV flight control. Several comparisons are conduced and analyzed in order to compare the accuracy and the convergence of different approaches usually applied in navigation data fusion purposes. The last non linear filter algorithm developed is the Cubature Kalman Filter CKF which provides more accurate estimation with more stability in Tracking data fusion application. In this work, CKF is compared with SPKF and EKF in ideal conditions and during GNSS outliers supposed to occur during specific interval of time, innovation based adaptive approach is selected and used to modify the covariance calculation of the non linear filters performed in this paper. Interesting results are observed, discussed with real perspectives in navigation data fusion for real time applications. Three parallel modified algorithms are simulated and compared to non-adaptive forms according to Root Mean Square Error (RMSE) criteria.

关键词： IMU MEMS GPS GNSS Kalman Filtering Cubature Rule Sigma points Unscented Kalman Filter

Existence and Stability of Equilibrium points in the Robe’s Restricted Three-Body Problem with Variable Masses

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International Journal of Astronomy and Astrophysics 2013年第2期3卷 113-122页

作者： Jagadish Singh Oni Leke Department of Mathematics Faculty of Science Ahmadu Bello University Zaria Nigeria Department of Mathematics Statistics and Computer Science College of Science University of Agriculture Makurdi Nigeria

The positions and linear stability of the equilibrium points of the Robe’s circular restricted three-body problem, are generalized to include the effect of mass variations of the primaries in accordance with the unified Meshcherskii law, when the motion of the primaries is determined by the Gylden-Meshcherskii problem. The autonomized dynamical system with constant coefficients here is possible, only when the shell is empty or when the densities of the medium and the infinitesimal body are equal. We found that the center of the shell is an equilibrium point. Further, when k﹥1;k?being the constant of a particular integral of the Gylden-Meshcherskii problem;a pair of equilibrium point, lying in the -plane?with each forming triangles with the center of the shell and the second primary exist. Several of the points exist depending on k;hence every point inside the shell is an equilibrium point. The linear stability of the equilibrium points is examined and it is seen that the point at the center of the shell of the autonomized system is conditionally stable;while that of the non-autonomized system is unstable. The triangular equilibrium points on the -plane of both systems are unstable.

关键词： Robe’s Problem Meshcherskii Law GMP Equilibruim points

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PEOPLE & points

Beijing Review 2019年第23期 10-11页

NEW AMBASSADOR TO JAPAN Kong Xuanyou, former Vice Foreign Minister and special representative of the Chinese Government on Korean Peninsula affairs, took up his new post as China’s ambassador to Japan on May 30.

关键词： PEOPLE points

THE INFLUENCE OF ELECTRO-ACUPUNCTURE AT NEIGUAN AND FIVE SHU points OF TWELVE REGULAR MERIDIANS AT DIFFERENT TIME ON SYSTOLIC TIME INTERVAL OF NORMAL YOUNG ADULTS

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World Journal of Acupuncture-Moxibustion 1994年第1期4卷 40-45页

作者： Li Lei, Chen Hanping, Xi Yongjiang, Gu JieShanghai University of TCM, Shanghai 200032, China

The influence of electro-acupuncture at Neiguan (PC 6)and five shu points of twelve regular meridians at different time on systolic time interval (ST I) of normal young adultswere studied with 6×6 Latin square design in this *** 12 groups according to 12 regular merldlans,the STIs were measured respectively just before and after electro-acupuncture on Neiguan andfive shu points at 00:00,04:00,08:00,12:00,16:00 and 20:00 of a *** was found thatexcept the PEPI and PEPI/LVETI ratio among Shenmen(HT 7),Shaochong(HT 9)and Neiguan,Guanchong(TE)and Yemen(TE 2)points,the effects of electro-acupuncture at Neiguan pointand five shu points of twelve regular meridians on the indices of STI of normal young adults wereshowing no slgnificant *** also was no difference in different *** the indices ofSTI were changed when electroacupuncture on the different points of different meridians at differenttime.

关键词： Electro-acupuncture Neiguan Five Shu points Systolic time interval

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Mining Corner points on the Generic Shapes

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Open Journal of Applied Sciences 2013年第1期3卷 10-15页

作者： M. Sarfraz Z. N. K. Swati 1Department of Information Science Kuwait University Adailiya Campus P.O. Box 5969 Safat 13060 Kuwait Department of Computer Science and Information Technology Karakoram International University Gilgit-Baltistan Pakistan

This paper designs and implements a corner detection algorithm for mining corner points on the generic shapes. The proposed corner detector detects corners by using combination of one rectangle and two ellipses (REE) with different parameter settings in their descriptions. REE combination slides along the boundary of the shape and records number of boundary points in each rectangle and ellipses. REE setup represents both local and global views of the image outline. The proposed technique presents a natural corners detection methodology to detect all true corners accurately. This technique is consistent with human vision system.

关键词： mining corner points corner detector planar curves generic shapes

Artificial Equilibrium points in the Low-Thrust Restricted Three-Body Problem When Both the Primaries Are Oblate Spheroids

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International Journal of Astronomy and Astrophysics 2018年第4期8卷 406-424页

作者： Amit Mittal Krishan Pal Department of Mathematics A.R.S.D College University of Delhi New Delhi India Department of Mathematics Maharaja Agrasen College University of Delhi New Delhi India

This paper studies the existence and stability of the artificial equilibrium points (AEPs) in the low-thrust restricted three-body problem when both the primaries are oblate spheroids. The artificial equilibrium points (AEPs) are generated by canceling the gravitational and centrifugal forces with continuous low-thrust at a non-equilibrium point. Some graphical investigations are shown for the effects of the relative parameters which characterized the locations of the AEPs. Also, the numerical values of AEPs have been calculated. The positions of these AEPs will depend not only also on magnitude and directions of low-thrust acceleration. The linear stability of the AEPs has been investigated. We have determined the stability regions in the xy, xz and yz-planes and studied the effect of oblateness parameters A1(0A1?and ?A2(0A2<1) on the motion of the spacecraft. We have found that the stability regions reduce around both the primaries for the increasing values of oblateness of the primaries. Finally, we have plotted the zero velocity curves to determine the possible regions of motion of the spacecraft.

关键词： Restricted Three-Body Problem Artificial Equilibrium points Low-Thrust Stability Oblate Spheroid Zero Velocity Curves