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Clinical value of phenylephrine testing in the upper and lower eyelids of patients with aponeurotic and congenital eyelid ptosis

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International Journal of Ophthalmology(English edition) 2022年第9期15卷 1444-1452页

作者： Ozgun Melike Gedar Totuk Meltem Guzin Altinel Ayse Yagmur Kanra Umit Aykan Atakoy Dunyagoz Hospital BakirkoyIstanbul 34158Turkey Department of Ophthalmology Fatih Sultan Mehmet Training and Research HospitalAtasehirIstanbul 34752Turkey Department of Ophthalmology Sisli Hamidiye Etfal Training and Research HospitalSariyerIstanbul 34453Turkey Etiler Dunyagoz Hospital BesiktasIstanbul 34337Turkey

·AIM:To characterize the phenylephrine test in aponeurotic and congenital eyelid ptosis,to determine the appropriate timing of the phenylephrine test,and to assess the responses of the upper and lower eyelids.·METHODS:This was a retrospective analysis of 140 eyes of 87 patients(mean age 52.29±16.45 y;22 males,65 females)with upper eyelid *** 88.6%had aponeurotic and 11.4%had congenital *** the evaluation of the responses of the upper and lower eyelids to topical 2.5%phenylephrine,the scleral show height,the marginal reflex distance(MRD)between the inferior margin of the upper eyelid and pupillary light reflex(MRD1),and between the central portion of the lower eyelid and pupillary light reflex(MRD2)were measured at the 2^(nd),5^(th),and15^(th)*** changes of MRD1 and MRD2 with time(ΔMRD1 andΔMRD2)were evaluated.·RESULTS:The mean MRD1,*** scleral show heights increased within 5 min after testing,remaining largely stable between the 5^(th)-15^(th)*** percentage of eyes with a greater response in MRD1 increased with increased severity of ptosis(Pphenylephrine testing than congenital *** mild ptosis group had lower scleral show measurements and higherΔMRD2 ***ΔMRD1 andΔMRD2 values were poorly correlated in all measurement times.·CONCLUSION:Performing the phenylephrine test 5 min after instilling the reagent is adequate to assess the maximum response of the upper and lower *** upper and lower eyelid responses in phenylephrine testing are poorly ***,theΔMRD2 is related with baseline scleral show degree that may be a postoperative predictive *** studies are necessary to determine the relationship between the responses of the lower eyelids to phenylephrine testing.

关键词： eyelid ptosis phenylephrine testing scleral show aponeurotic ptosis congenital ptosis

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