检索结果-南通市图书馆

Exposure to perfluorooctane sulfonate reduced cell viability and insulin release capacity of β cells

Journal of Environmental Sciences 2022年第5期34卷 162-172页

作者： Weiping Qin Xiaomin Ren Lixia Zhao Lianghong Guo State Key Laboratory of Environmental Chemistry and Eco-toxicology Research Center for Eco-environmental SciencesChinese Academy of SciencesBeijing 100085China Institute of Environmental and Health Sciences China Jiliang UniversityHangzhou 310018China

Per-and polyfluoroalkyl substances(PFAS)are found to have multiple adverse outcomes on human ***,epidemiological and toxicological studies showed that exposure to PFAS had adverse impacts on pancreas and showed association with insulin *** explore how PFAS may contribute to diabetes,we studied impacts of perfluorooctane sul-fonate(PFOS)on cell viability and insulin release capacity of pancreatic β cells by using in vivo and in vitro *** found that 28-day administration with PFOS(10 mg/(kg body weight·day))caused reductions of pancreas weight and islet size in male *** admin-istration also led to lower serum insulin level both in fasting state and after glucose infusion among male *** cell-based in vitro bioassay,we used mouse β-TC-6 cancer cells and found 48-hr exposure to PFOS decreased the cell viability at 50 μmol/*** measuring insulin content in supernatant,48-hr pretreatment of PFOS(100 μmol/L)decreased the insulin re-lease capacity of β-TC-6 cells after glucose *** these concentrations were higher than the environmental concentration of PFOS,it might be reasonable for high con-centration of PFOS to exert observable toxic effects in mice considering mice had a faster removal efficiency of PFOS than *** exposure(50 μmol/L)to β-TC-6 cells induced intracellular accumulation of reactive oxidative specie(ROS).Excessive ROS induced the re-active toxicity of cells,which eventually invoke apoptosis and *** in this study provide evidence for the possible causal link of exposure to PFOS and diabetes risk.

关键词： perfluorooctane sulfonate Insulin secretion Pancreaticβcells Apoptosis Reactive oxidative species

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sorption of perfluorooctane sulfonate(PFOS) including its isomers on hydrargillite as a function of pH,humic substances and Na2SO4

引用

Journal of Environmental Sciences 2022年第1期34卷 263-272页

作者： Jean-Noel Uwayezu Leo W.Y.Yeung Mattias Bäckström Man-Technology-Environment Research Centre(MTM) Örebro University70182ÖrebroSweden

perfluorooctane sulfonate(PFOS)is a persistent organic pollutant(POP)and emergent contaminant that are widespread in the *** the mechanisms controlling the distribution of PFOS and its isomers between hydrargillite and the water phase is important in order to study their redistribution and mobility in the *** study investigated the effects of pH,humic acid,fulvic acid and Na_(2)SO_(4) on sorption of PFOS isomers to hydrargillite.A mixture of PFOS isomers was spiked into water and hydrargillite was added to the system and shaken for one day;the system was tested with different aqueous *** of PFOS isomers in the aqueous phase were quantified using an ultra-performance liquid chromatograph coupled to a triple quadrupole mass *** results showed that the distribution coefficients of PFOS isomers were found to be 0.76,0.71,0.93 and 0.90 at pH 6.5,for 3-/4-/5-PFOS,6-/2-PFOS,L-PFOS and total PFOS *** distribution coefficients increased at lower pH and decreased at alkaline *** presence of humic substances(HS)increased the sorption slightly at the environmental pH of 6.5,although a competition effect was observed during acidic conditions.A tendency of PFOS distribution to hydrargillite in the presence of Na_(2)SO_(4) was like its behavior in the presence of HS although the mechanisms behind the sorption were interpreted *** study revealed that L-PFOS was readily sorbed when no other chemicals were added or in 20 mg/L FA or 100 mg/L Na_(2)SO_(4).We suggest that an increase in PFOS sorption in the presence of HS may be due to hydrophobic mechanisms while Na_(2)SO_(4) contributed to increased sorption through ionic strength effects.

关键词： Hydrargillite perfluorooctane sulfonate Sorption Humic substances Electrostatic,Ionic strength

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fluorescence detection of perfluorooctane sulfonate in water employing a tetraphenylethylene-derived dual macrocycle Bowtie Cyclophane

引用

Chinese Chemical Letters 2022年第3期33卷 1493-1496页

作者： Sheng-Nan Lei Huan Cong Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry&School of Future TechnologyUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100190China

Because the widely used perfluorooctane sulfonate(PFOS) is harmful to both environment and human health, it is of great significance and urgency to develop sensitive and selective sensors for the detection of trace PFOS in water. In this study, a tetraphenylethylene-derived macrocycle Bowtie Cyclophane has been developed as a fluorescent sensor based on aggregation-induced emission enhancement and fluorochromism. Sensitive detection of PFOS has been achieved with a limit of detection(LOD) of47.3 ± 2.0 nmol/L(25.4 ± 1.1 μg/L) accompanied by visual fluorescence color changes.

关键词： Fluorescence Aggregation perfluorooctane sulfonate Tetraphenylethylene Macrocycle

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Toxic effect of perfluorooctane sulfonate on plants in vertical-flow constructed wetlands

引用

Journal of Environmental Sciences 2020年第6期32卷 176-186页

作者： Rong Li Tianhao Tang Weichuan Qiao Jun Huang Department of Environmental Engineering College of Biology and the EnvironmentNanjing Forestry UniversityNanjing 210037China School of Environment Beijing Key Laboratory for Emerging Organic Contaminants Control(BKLEOC)State Key Joint Laboratory of Environment Simulation and Pollution Control(SKLESPC)Tsinghua UniversityBeijing 100084China

Per-and polyfluoroalkyl substances(PFASs)can be taken up and bioaccumulated in plants,but the toxic mechanisms of PFASs on wetland plants are still *** present study,the toxic influences of perfluorooctane sulfonate(PFOS)on Eichhornia crassipes(***)and Cy perus alternifolius(***)in a vertical-sub surface-flow constructed wetland were *** results showed that *** was more tolerant to PFOS stress than ***,and the growth and chlorophyll synthesis of the two plants were promoted by low concentration(<0.1 mg/L)of PFOS,and the chlorophyll synthesis was inhibited by high concentration(10 mg/L)of PFOS but the growth did not change *** catalase activity and malondialdehyde content in the leaves of the two plants increased,peroxidase activity decreased under exposure to high concentrations of PFOS,and superoxide dismutase activity did not *** PFOS stress,the membrane of plant leaves and the cell structure of the two wetland plants were destroyed,and the mitochondrial contour of root cells became *** analysis showed that the expression levels of genes related to cell wall formation,the cell apoptosis pathway,material synthesis,and metabolism in the plants were changed by *** in fluorogenic quantitative real time polymerase chain reaction(RT-qPCR)also confirmed that the photosynthesis system of *** was inhibited,while that of *** was promoted.

关键词： perfluorooctane sulfonate Wetland plants Toxicity Vertical-flow constructed wetlands Effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Removal,distribution and plant uptake of perfluorooctane sulfonate(PFOS)in a simulated constructed wetland system

引用

Frontiers of Environmental Science & Engineering 2021年第2期15卷 43-53页

作者： Weichuan Qiao Rong Li Tianhao Tang Achuo Anitta Zuh Department of Environmental Engineering College of Biology and the EnvironmentNanjing Forestry UniversityNanjing 210037China

A vertical-flow constructed wetland(VFCW)was used to treat simulated domestic sewage containing perfluorooctane sulfonate(PFOS).The removal rate of PFOS in the domestic sewage was 93%–98%,through soil adsorption and plant uptake,suggesting that VFCWs can remove PFOS efficiently from *** removal of PFOS in the VFCW was dependent on soil adsorption and plant uptake;moreover,the percentage of soil adsorption was 61%–89%,and was higher than that of the plants uptake(5%–31%).The absorption capacity of Eichhornia crassipes(***)(1186.71 mg/kg)was higher than that of Cyperus alternifolius(***)(162.77 mg/kg)under 10 mg/L PFOS,and the transfer factor of PFOS in *** and *** was 0.04 and 0.58,respectively,indicating that PFOS is not easily translocated to leaves from roots of wetland plants;moreover,uptake of PFOS by *** was more than that of *** because the biomass of *** was more than that of *** and the roots of *** can take up PFOS directly from wastewater while *** needs to do so via its roots in the *** concentration of 10 mg/L PFOS had an obvious inhibitory effect on the removal rate of total nitrogen,total phosphorus,chemical oxygen demand,and ammonia nitrogen in the VFCW,which decreased by 15%,10%,10%and 12%,*** with PFOS in the wastewater reduced the bacterial richness but increased the diversity in soil because PFOS stimulated the growth of PFOS-tolerant strains.

关键词： Vertical-flow constructed wetland perfluorooctane sulfonate Wetland plants Soil microbial community Effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of temperature on the sorption and desorption of perfluorooctane sulfonate on humic acid

引用

Journal of Environmental Sciences 2010年第3期22卷 355-361页

作者： Chengxia Jia, Chun You, Gang Pan State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China

Sorption and desorption of perfluorooctane sulfonate （PFOS） on humic acid at different temperatures were studied. It was found that the sorption process could be modeled with power kinetic equation very well, suggesting that diflusion predominated the sorption of PFOS on the humic acid. The sorption capacity was doubled when the temperature increased from 5 to 35°C, and thermodynamics parameters △G0 was calculated to be –7.11 to –5.04 kJ/mol, △H0 was 14.2 kJ/mol, and △S 0 was 69.5 J/（mol·K）, indicating that the sorption was a spontaneous, endothermic, and entropy driven process. Desorption hysteresis occurred at all studied temperatures which suggested that humic acid may be an important sink of PFOS in the environment.

关键词： perfluorooctane sulfonate sorption desorption temperature humic acid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Toxicity of perfluorononanoic acid and perfluorooctane sulfonate to Daphnia magna

引用

Water Science and Engineering 2015年第1期8卷 40-48页

作者： Guang-hua Lu Jian-chao Liu Li-sha Sun Lu-jin Yuan Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes of Ministry of Education College of Environment Hohai University

In order to study toxicological effects of perfluorononanoic acid （PFNA）, perfluorooctane sulfonate （PFOS）, and their mixtures （PFNA/ PFOS） on Daphnia magna （D. magna）, a suite of comprehensive toxicity tests were conducted, including a 48-h acute toxicity test, a 21-day chronic test, a feeding experiment, and a biomarker assay. D. magna were exposed to aqueous solutions of PFNA and PFOS （alone and in combination） at concentrations ranging from 0.008 to 5 mg/L. The survival, growth, and reproduction of D. magna were monitored over a 21- day life cycle. The biomarkers, including acetylcholinesterase （ACHE）, superoxide dismutase （SOD）, and catalase （CAT） activities, were determined after seven days of exposure. PFOS was more toxic than PFNA based on the results of the acute toxicity test. Perfluorinated compounds （PFCs） inhibited both growth and reproduction of D. magna during the testing period. The ingestion rates and the biomarkers, including ACHE, SOD, and CAT activities, were significantly inhibited by PFCs in most cases. Moreover, the combined effects related to the growth and reproduction showed the antagonistic effects of PFCs.

关键词： Toxicity effect Perfluorononanoic acid perfluorooctane sulfonate Daphnia magna Reproduction Ingestion rate Biomarker

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

perfluorooctane sulfonate and perfluorooctanoic acid in the fingernails of urban and rural children

引用

Science Bulletin 2010年第33期55卷 3755-3762页

作者： XU Lei,LIU Wei & JIN YiHe Key Laboratory of Industrial Ecology and Environmental Engineering of Ministry of Education,School of Environmental Science and Technology,Dalian University of Technology,Dalian 116024,China Key Laboratory of Industrial Ecology and Environmental Engineering of Ministry of Education School of Environmental Science and Technology Dalian University of Technology Dalian China

perfluorooctane sulfonate(PFOS)and perfluorooctanoic acid(PFOA)are two typical perfluorinated compounds(PFCs),found in a wide range of environmental media and organisms,including *** biomonitoring studies of body fluids have revealed that in many areas of the world the general population has been exposed to background levels of PFOS and *** has been suggested as a promising biopsy material for assessment of PFCs environmental *** the present study,PFOS and PFOA were quantified using high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)in fingernails of urban and rural children(N=93)aged 6-12 years.A questionnaire was conducted to determine factors that could influence the PFOS and PFOA levels in the *** levels of PFOS in urban children were significantly higher(geometric mean(GM)=328 ng/g)than those in rural children(GM=27 ng/g).In contrast,PFOA levels were significantly lower in the urban children compared with the rural *** positive correlation(R=0.53,P<0.05 for urban areas;R=0.71;P<0.001 for rural areas)between the PFOS and PFOA concentrations indicated they had similar *** PFOS and PFOA levels were higher in fingernail samples from children aged <9 years than in children aged ≥9 *** addition,females had higher PFOA levels than males,in both *** factors that significantly influenced PFOS and PFOA levels were dietary habits and socio-economic *** results of this study indicate fingernails are a suitable material for biomonitoring of PFCs environmental ***,the levels determined in the fingernail samples need to be first evaluated with regard to the levels determined in other samples,such as human serum.

关键词： perfluorooctane sulfonate perfluorooctanoic acid fingernails biomarker environmental exposure

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Protonation state effect of estrogen receptor α on the recognition mechanisms by perfluorooctane sulfonate and perfluorooctanoic acid:A computational study

Protonation state effect of estrogen receptor α on the reco...

引用

第二次全国计算毒理学学术会议暨中国毒理学会第一届计算毒理专业委员会第二次会议

作者：曹慧明张爱茜 Institute of Environment and Health Jianghan University State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of Science

Perfluoroalkyl acids(PFAAs) including the perfluorocarboxylated acids(PFCAs) and perfluorosulfonatedacids(PFSAs) are a group of highly stable man-made compounds used in surfactants,fluorinated polymers,and fire-resistant *** to the stable carbon-fluorine bonds,PFAAs exhibit unique thermal and acid resistance and hydroand oleophobic properties in the environment..Perfluorooctanoic acid(PFOA) and

关键词： estrogen receptor α perfluorooctanoic acid perfluorooctane sulfonate protonation state molecular dynamics simulation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Co-occurrence of per-and polyfluoroalkyl substances, heavy metals and polycyclic aromatic hydrocarbons and their composite impacts on microbial consortium in soil: A field study

引用

Pedosphere 2024年第4期34卷 736-748页

作者： Meng ZHANG Qing WANG Xin SONG Mukhtiar ALI Zhiwen TANG Xin LIU Zhuanxia ZHANG Shurong MA Jinhui BI Zhongyuan LI Key Laboratory of Saline-Alkali Vegetation Ecology Restoration Northeast Forestry University Key Laboratory of Soil Environment and Pollution Remediation Institute of Soil Science Chinese Academy of Sciences University of Chinese Academy of Sciences Center International Group Co. Ltd. China Construction Eighth Engineering Division Corp. Ltd.

This is the first study to report the co-occurrence of per-and polyfluoroalkyl substances（PFASs）, heavy metals, and polycyclic aromatic hydrocarbons（PAHs） and their impacts on the native microbial consortium in soil due to the long-term exposure. The PFASs, heavy metals, and PAHs were detected in soil samples collected at 2–6 m below the ground surface at different sampling locations in a steel-making factory. The total concentrations of PFASs varied from 6.55 to 19.79 ng g-1, with perfluorooctane sulfonate（PFOS）, perfluorobutane sulfonate, and 6:2 chlorinated polyfluorinated ether sulfonate（alternative of PFOS） being the predominant PFASs. The concentrations of arsenic, cadmium, and lead were detected in the ranges of 4.40–1 270.00,0.01–8.67, and 18.00–647.00 mg kg-1, respectively, and the concentration of total PAHs was detected in the range of 1.02–131.60 mg kg-1. The long-term exposure to mixed contaminants of PFASs, heavy metals, and PAHs led to lower richness and diversity of microbial communities in soil. The soil bacterial communities were mainly composed of Pseudomonas, norank＿p＿GAL15, Leptothrix, norank＿o＿Rokubacteriales, and Acinetobacter. Correlations between soil environmental factors and microbial communities indicated that cation exchange capacity and total phosphorus were two key factors in shaping the composition of native microbial communities. Furthermore, Arthrobacter, Leptothrix, and Sphingobium were found to be significantly positively correlated with PFAS concentrations, indicating that these genera could tolerate the stress exerted by PFASs, along with the stress imposed due to the presence of heavy metals or/and PAHs.

关键词： arsenic cation exchange capacity mixed contaminant native microbial community perfluorooctane sulfonate total phosphorus

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：