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Epidemiology of hospitalized pediatric glaucoma patients in Beijing Tongren Hospital

Chinese Medical Journal 2009年第10期122卷 1162-1166页

作者： QIAO Chun-yan WANG Liang-hai TANG Xin WANG Tao YANG Di-ya WANG Ning-li Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology & Visual Sciences Key Laboratory Beijing 100730 China Department of Ophthalmology Peking University Shougang Hospital Beijing 100144 China

Background No population-based assessment of the prevalence and incidence of pediatric glaucoma in China are available. Here we describe the spectrum of hospitalized pediatric glaucoma patients in Beijing Tongren Hospital in China.Methods We reviewed the charts of pediatric patients, from birth to 18 years old, with a discharge diagnosis of glaucoma in Beijing Tongren Hospital, from 2002 to 2008. All children were admitted for anti-glaucoma surgery, treating the sequelae of the glaucoma, or managing postoperative complications. We evaluated the demographic characteristics and the proportion of different glaucoma subtypes. Results pediatric patients （n=1452） accounted for 12.91% of the total glaucoma in-patients from 2002 to 2008, and at last data of pediatric glaucoma were presented for 1055 children who came from 28 provinces, municipalities and autonomous regions in China. Boys were more common in all subtypes and at all ages, with a total ratio of boys to girls of 2.32：1. Congenital glaucoma was the most common subtype, accounting for 46.07% in all patients and accounting for 69.95% in children under 3 years of age. The median presenting age of congenital glaucoma patients was 2 years. Patients with traumatic glaucoma were the second most common group （n=128, 12.13%）, and presented at older age （the median presenting age was 11 years）. The majority of traumatic glaucoma occurred in children between 10 and 15 years of age （n=72, 56.25%）. Aphakic glaucoma was the third most common （9.19%） subtype. Conclusions Congenital glaucoma is the most prevalent glaucoma subtype in hospitalized pediatric patients in Beijing Tongren Hospital. The prevention and treatment of traumatic glaucoma can reduce the incidence of visual damage in developing countries. Close follow-up for glaucoma is important after pediatric cataract surgery.

关键词： pediatric glaucoma hospitalization proportion epidemiology

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Profile of pediatric glaucoma patients in Shanghai Eye, Ear, Nose and Throat Hospital

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Chinese Medical Journal 2014年第8期127卷 1429-1433页

作者： Fang Yuan Long Qingqing Guo Wenyi Sun Xinghuai Department of Oplathalmology and Vision Science Eye Ear Nose and Throat Hospital Shanghai Medical College Fudan University Shanghai 200031 China State Key Laboratory of Medical Neurobiology Institutes of Brain Science Fudan University Shanghai 200031 China Department of Ophthalmology Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200011 China

Background The extent of our knowledge of the epidemiology of pediatric glaucoma in China is limited. To better characterize the epidemiology of pediatric glaucoma in eastern China, we report the clinical profile, etiologies, and treatment modalities in patients 〈18 years of age in Shanghai Eye, Ear, Nose and Throat Hospital. Methods The medical records of patients presenting glaucoma between January 2003 and December 2010 were retrospectively reviewed. The demographic characteristics, the proportion of different glaucoma subtypes and surgical precedures were collected and analyzed. Results A total of 1 142 eyes of 734 pediatric patients （500 males） were included. Congenital glaucoma was the leading subtype, accounting for 47.55% of all patients. The ratio of boys to girls was 2.5：1. Patients with congenital glaucoma affecting both eyes accounted for 72.5% of all patients examined. Patients with primary juvenile glaucoma were the second most common group （n=125, 17.03%）. Traumatic glaucoma was the third most common subtype （n=81, 11.03%）. The type of surgery was related to the subtype of glaucoma. Conclusions Congenital glaucoma, primary juvenile glaucoma, and traumatic glaucoma are the most prevalent subtypes in pediatric glaucoma patients in Shanghai Eye, Ear, Nose and Throat Hospital. The characteristics of congenital glaucoma in China are similar to those in Western countries.

关键词： pediatric glaucoma proportion epidemiology congenital glaucoma primary juvenile glaucoma

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Dealing with pediatric glaucoma: from medical to surgical management-a narrative review

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Annals of Eye Science 2021年第3期6卷 30-36页

作者： Matteo Sacchi Rosario Alfio Umberto Lizzio Gianluca Monsellato University Eye Clinic San Giuseppe HospitalMilanoItaly

pediatric glaucoma is a potentially sight-threatening disease and is considered the second leading cause of treatable childhood *** glaucoma is a clinical entity including a wide range of conditions:primary congenital glaucoma,glaucoma secondary to ocular(e.g.,aniridia,Peter’s anomaly),or systemic disease(e.g.,Sturge Weber)and glaucoma secondary to acquired condition(pseudophakic,traumatic,uveitic glaucoma).The treatment algorithm of childhood glaucoma is a step-by-step approach,often starting with surgery,as in primary congenital glaucoma *** therapy is also crucial in the management of pediatric *** we reported the results of the randomized,controlled,clinical trials carried out in children treated with topical anti-glaucoma *** is worth knowing that prostaglandin analogues showed an excellent systemic safety profile,while serious systemic events have been reported in children taking topical *** surgery is the first surgical option in patients diagnosed with primary congenital glaucoma,with ab interno and ab externo approaches showing similar *** in children can be troublesome,as mitomycin C(MMC)can lead to bleb complications and a higher endophthalmitis rate than in *** drainage devices(GDD)are no longer a last resort and can be considered a suitable option for the management of uncontrolled pediatric glaucoma after angle surgery failure.

关键词： pediatric glaucoma anti-glaucoma medication angle surgery trabeculectomy glaucoma drainage device(GDD)

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A Case of Refractory Childhood glaucoma Secondary to Weill-Marchesani Syndrome:Management with Combined CO_(2) Laser-Assisted Sclerectomy Surgery and Trabeculectomy

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Chinese Medical Sciences Journal 2022年第2期37卷 159-163页

作者： Yang Zhang Ailing Bian Anyi Liang Fei Mo Gangwei Cheng Department of Ophthalmology Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature,short and stubby hands and feet,language disorders and mental *** developed bilateral angle closure glaucoma,ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani *** child was successfully treated by combined CO_(2) laser-assisted sclerectomy surgery and trabeculectomy.

关键词： pediatric glaucoma refractory glaucoma surgery Weill-Marchesani syndrome CO_(2)laser

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