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papillary Carcinoma Derived from Ovarian Mature Cystic Teratoma: A New Case Report and Literature Review

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Case Reports in Clinical Medicine 2014年第4期3卷 197-202页

作者： Ihsane Souaf Hinde El Fatemi Amal Bennani Chbani Leila Hammas Nawale Harmouch Tawfik Afaf Amarti Department of Pathology Hassan II Teaching Hospital Fez Morocco

Introduction: papillary carcinoma arising from thyroid tissue in mature cysticteratoma (MCT) of the ovary is extremely rare, and it is not easy to diagnose preoperatively. No clinical, no radiological, no biological signs are specific to malignant transformation. Case presentation: A 51-year-old woman had a left ovarian tumor measuring approximately 18 cm diameter with malignant transformation of a mature cysticteratoma, who was diagnosed postoperatively with follicular variant of papillary thyroid carcinoma. A laparoscopic hysterectomy and left salpingo-oophorectomy were performed. During surgery, there were no signs of invasion or metastasis. Conclusion: Consideration should be given to thyroidectomy followed by total-body scanning and serum studies for foci of thyroid carcinoma and adjuvant therapy with thyroidectomy and radio ablation if residual disease is identified.

关键词： Ovarian Teratoma papillary Carcinoma Malignant Transformation Thyroid Ovarian Neoplasm

papillary Fibroelastoma of the papillary Muscle of the Tricuspid Valve: Reconstruction of the papillary Muscle

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Open Journal of Thoracic Surgery 2013年第3期3卷 69-72页

作者： Susumu Isoda Tamizo Kimura Kenji Nishimura Nozomu Yamanaka Shingo Nakamura Tadaaki Maehara Department of Cardiovascular Surgery National Defense Medical College Tokorozawa Japan.

Cardiac papillary fibroelastoma is the third most frequent primary cardiac tumor, after myxoma and fibroma. A papillary fibroelastoma that arises from the papillary muscle is rare. We removed a papillary fibroelastoma located at the anterior papillary muscle of the tricuspid valve. The papillary muscle needed reconstruction. We used the loop technique to adjust the length of the papillary muscle and performed annuloplasty by using an artificial ring.

关键词： papillary Fibroelastoma papillary Muscle Tricuspid Valve Valve Plasty

papillary thyroid cancer and inflammatory bowel disease:Is there a relationship?

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World Journal of Gastroenterology 2013年第7期19卷 1079-1084页

作者： Irene S Sonu Wojciech Blonski Ming Valerie Lin James Lewis Faten Aberra Gary R Lichtenstein Division of Internal Medicine Stanford University Hospital and ClinicsStanfordCA 94305United States Division of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Division of Digestive Diseases University of CincinnatiCincinnatiOH 45229United States Division of Gastroenterology Hospital of the University of PennsylvaniaUniversity of Pennsylvania School of MedicinePhiladelphiaPA 19103United States

AIM:To formally study age of diagnosis of papillary thyroid cancer(PTC) in inflammatory bowel disease(IBD) patients and evaluate the prevalence of PTC in IBD patients compared to a control *** that patients with IBD are more likely to be diagnosed with PTC than a control population.A retrospective cohort analysis was performed using the University of Pennsylvania Health System's electronic *** from 1998-2009 were included in the search,and patients in the cohort were selected based on ICD-9 *** criteria included the diagnosis of Crohn's disease(CD) or ulcerative colitis(UC) and the concurrent diagnosis of thyroid cancer in comparison to a control *** these methods 912 patients with CD and 1774 with UC were compared to 1638 diverticulitis and 19 447 asthma *** were performed using corrected chisquare *** primary outcome for this study was the diagnosis of *** to conduct this study was obtained by the Institutional Review Board at the University of ***:The mean age was 47.5 years(range:18-102 years) and 66% patients were *** analysis of variance model was used to compare the age of PTC diagnosis between the CD,UC,asthma and diverticulitis groups,and a statistically significant difference in age at PTC diagnosis was noted across all groups(F = 6.35,df = 3,P = 0.0006).The age of PTC diagnosis in CD patients was statistically significantly lower than UC,asthma,and diverticulitis patients(average PTC diagnosis age for CD 25,UC 49,asthma 45,diverticulitis 63).After covarying for sex and age in 2009,the difference in age at PTC diagnosis remained statistically significant(F = 4.13,df = 3,P = 0.0089).A total of 86 patients were diagnosed with *** patients(0.5%) with UC were diagnosed with *** with UC were not shown to be more likely to develop PTC [odds ratio(OR):1.544,95%CI 0.767-3.108] compared to asthma *** patients(0.4%) with CD were

关键词： papillary thyroid cancer Inflammatory bowel disease Crohn disease Ulcerative colitis

Immediate balloon deflation method in endoscopic papillary large balloon dilation for extraction of difficult bile duct stones

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Open Journal of Gastroenterology 2013年第2期3卷 142-147页

作者： Duk Joo Choi Yeon Suk Kim Jung Ho Kim Yang Suh Ku Min Su Ha Ju Hyeon Kim Department of Internal Medicine Gachon University Gil Medical Center Incheon South Korea

Background/Aims: Recently, endoscopic papillary large balloon dilation (EPLBD) using a large balloon (12 - 20 mm) for extraction of difficult common bile duct (CBD) stones has been widely accepted with favorable outcomes. However, there is no consensus with regard to the ballooning time. The aim of our study was to evaluate the efficacy and safety of immediate balloon deflation in EPLBD for the treatment of difficult bile duct stone. Methods: This was a retrospective study of 80 consecutive patients with bile duct stones who were treated with an immediate balloon deflation method in EPLBD combined with endoscopic sphincterotomy (EST) between January 2010 and December 2012. Overall success rate, success rate at first ERCP, and the frequency of mechanical lithotripsy for complete stone removal were assessed for efficacy and safety was evaluated by assessing major complications. Results: Overall success rate for complete stone removal was high (78/80, 97.5%) and success rate for complete stone removal at first ERCP was 86.3% (69/80). The use of mechanical lithotripsy was 0% (0/80). The overall complication rate was favorable (5/80, 6.3%). PostERCP pancreatitis was observed in 3 patients (two: mild, one: moderate). In subgroup analysis, the presence of periampullary diverticulum was the only factor affecting the success rate at first ERCP. Conclusion: This study demonstrated the favorable outcome of immediate balloon deflation for treatment of difficult CBD stones and can be considered for clinical application.

关键词： Endoscopic papillary Large Balloon Dilation Ballooning Time Immediate Balloon Deflation Difficult Bile Duct Stone

Unusual Cystic and papillary Appearance of Brain Metastasis from papillary Lung Adenocarcinoma on MRI. Radiologic-Pathologic Correlations in Two Similar Cases

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Advances in Lung Cancer 2020年第2期9卷 17-23页

作者： Patrick Mailleux Marie Mailleux Anne-Sophie Marchand Department of Imaging Clinique St Luc Bouge Belgium Department of Oncology Clinique St Luc Bouge Belgium Department of Imaging CHU UCL Namur Namur Belgium

We report two cases of brain metastasis from a lung adenocarcinoma. Magnetic Resonance Imaging (MRI) appearance was closely correlated with the macroscopic and microscopic findings that showed multiples nodules of a w... 详细信息

关键词： Brain MRI Metastasis Lung Adenocarcinoma papillary

Modulation of Interval–Force Dependence of Rat papillary Muscle at Acute and Course Exposure of Amiodarone

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Pharmacology & Pharmacy 2012年第3期3卷 342-347页

作者： Sergey Afanasiev Dina Kondratyeva Sergey Popov Roman Batalov Federal State Budgetary Institution Research Institute for Сardiology of Siberian Branch under the Russian Academy of Medical Sciences Tomsk Russia.

Change of interval–force dependence of rat papillary muscles at acute and course use of amiodarone was investigated. Methods. The experiments were performed on isolated papillary muscles of Wistar rats. The extrasystolic (0,2-1,5 s), postextrasystolic contractions and post-rest (4-60 s) reactions of rat left papillary muscles perfused Krebs-Henseleit solution with amiodarone (1 μM) and papillary muscles of rat treated amiodarone in dose 20 mg/kg/day for 14 days were investigated. Results. It has been found that both acute and course use of amiodarone decreases the amplitude of extrasystolic contraction. At the same time, only acute use of amiodarone leads to additional enhancement of potentialtion of contractile response at extrasystolic impulse and performance of post-rest test. Conclusion was made, that both acute and course use of amiodarone decreases excitability of cardiomyocytes but only at course use this antiarrythmic drug increases effective refractory period of myocardium. Acute exposure of amiodarone is accompanied with change of functional state of cardiomyocyte sarcoplasmatic reticulum.

关键词： Acute and Course Amiodarone Sarcoplasmic Reticulum Function Postextrasystolic and Post-Rest Contractions papillary Muscles of Rat

Thyroid papillary Carcinoma in a Branchial Cleft Cyst—A Case Report

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Journal of Cancer Therapy 2017年第3期8卷 278-285页

作者： Chariton E. Papadakis Alexandros Ladias Theognosia S. Chimona Michail Gavriilidis Maria Zisoglou Efklidis Proimos ENT Department Chania General Hospital Chania Greece 1st Pathology Department Medical School University of Athens Athens Greece

Objective: Report a rare case of a thyroid papillary carcinoma situated within a branchial cleft cyst. Case presentation: A 40-year-old male was referred to our department for a lateral neck mass assessment. Physical examination revealed a solitary palpable, painless, moveable neck mass. Assessment included complete nasal, pharynx and larynx endoscopy, neck computed tomography, and fine needle aspiration biopsy. Treatment was surgical excision of the neck mass. Histopathology confirmed a branchial cleft cyst with papillary thyroid carcinoma growth at a site. A neck and thyroid ultrasound showed presence of thyroid gland nodules (one of which with micro calcifications). Thyroid fine needle aspiration biopsy performed, was high suspicious for malignancy (BETHESDA V). Patient underwent total thyroidectomy and histopathology revealed papillary thyroid carcinoma. Conclusion: Although rarely, it is possible to face an unexpected malignancy within a clinically benign neck lesion. A thorough diagnostic work-up enables early identification of aforementioned potential malignancy. A diagnostic dilemma that arises in such cases is between primary or metastatic disease and a thyroid carcinoma arising from ectopic thyroid tissue.

关键词： Thyroid Cancer papillary Carcinoma Branchial Cleft Branchial Cyst

Hyperthyroidism Due to papillary Thyroid Carcinoma Associated with Ductal Breast Carcinoma

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Case Reports in Clinical Medicine 2014年第8期3卷 479-486页

作者： Maria de Fátima Borges Ilka Mara Borges Botelho Modolo Rodrigo Gimenez Pissutti Modolo Lilian Carla Silva Luciene Mayumi Sato Rogério Costa Tiveron Delcio Scandiuzzi Marcus Aurelho Lima Discipline of Endocrinology Federal University of Triangulo Mineiro Uberaba Brazil

Thyroid tumors are usually associated with euthyroidism, and hyper functioning tumors are rare. There are few reports of carcinomas associated with hyperthyroidism. The aim of this study is to describe a case of hyper functioning papillary carcinoma associated with breast carcinoma. We present a 46-year-old woman that was referred for investigation of thyroid and breast nodules detected by routine ultrasound. She presented with hyperthyroidism and enlarged left thyroid lobe with fibroelastic consistency. Investigation demonstrated papillary carcinoma with follicular hyperactivity and invasive ductal carcinoma of the breast. The patient developed metastases 6 months later and died. This study demonstrates that hot thyroid nodules may harbor malignant tumors and should be punctured. The association with breast adenocarcinoma and the unfavorable outcome suggest higher aggressiveness of this tumor in the presence of hyperthyroidism.

关键词： papillary Carcinoma Hyperthyroidism Breast Carcinoma Thyroid Metastasis

Efficacy and safety of endoscopic papillary balloon dilation for the removal of bile duct stones: Data from a “real-life” multicenter study on Dilation-Assisted Stone Extraction

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World Journal of Gastrointestinal Endoscopy 2016年第18期8卷 646-652页

作者： Roberto Di Mitri Filippo Mocciaro Socrate Pallio Giulia Maria Pecoraro Andrea Tortora Claudio Zulli Simona Attardo Attilio Maurano Gastroenterology and Endoscopy Unit ARNAS Civico-Di Cristina-Benfratelli Hospital Endoscopy Unit Policlinico G.Martino Messina University Endoscopy Unit Amico Gaetano Fucito Hospital

AIM To report data on Dilation-Assisted Stone Extraction(DASE) use in clinical practice and its efficacy and safety trough three Italian referral centers for biliopancreatic diseases treatment. METHODS From January 2011 to December 2015 we collected data on 120 patients treated with DASE. Technical success was obtained when the endoscopist was able to place the balloon trough the papilla inflating the balloon until the final diameter for an adequate time(at least 30 s). Clinical success was obtained after complete stone removal(no remaining stones were visible at the cholangiogram).RESULTS Forty-nine male(40.8%) and 71 female(59%) were enrolled. The mean age was 67.8 years ± 15.7. The mean common bile duct(CBD) dilation was 19.2 mm± 3.9 and the mean size of stones 15.8 ± 2.9. DASE was applied as first approach in 38%(62% after initial failure of stones extraction). Technical and clinical success was of 91% and 87% respectively. In those in which DASE failed alternative treatment were adopted. After DASE 18% of patients experienced a complication(bleeding 9%, pancreatitis 8%, perforation 0.8%). At univariable analysis, elective endoscopic retrograde cholangiopancreatography(P = 0.031), DASE as first approach(P = 0.032), and cannulation of major papilla followed by guidewire insertion(P = 0.004) were related to low risk of complications. Pre-cut was related to an increased risk of complications(P = 0.01). CONCLUSION DASE allowed a higher first-session success rate and can be consider a valid alternative to endoscopic sphincterotomy not only for bigger CBD stones.

关键词： Endoscopic retrograde cholangiopancreatography Dilation-Assisted Stone Extraction Common bile duct stone Endoscopic sphincterotomy Endoscopic papillary balloon dilation