检索结果-南通市图书馆

Anti-oxidation properties of leaves, skin, pulp, and seeds extracts from green papaya and their anticancer activities in breast cancer cells

引用

Journal of Cancer Metastasis and Treatment 2018年第1期4卷 300-314页

作者： Shrefa A.Hadadi Haiwen Li Reza Rafie Paul Kaseloo Sarah M.Witiak Rafat A.Siddiqui Food Chemistry and Nutrition Science Laboratory Virginia State UniversityPetersburgVA 23806USA Cooperative Extension Agricultural Research StationCollege of AgricultureVirginia State UniversityPetersburgVA 23806USA Department of Biology College of Natural and Health SciencesVirginia State UniversityPetersburgVA 23806USA

Aim:Breast cancer is typically detected either during a screening examination or after a woman notices a *** cancers have different phenotypes depending on the presence/absence of an estrogen receptor(ER)and/or an epidermal growth factor(Her-2)*** objective of the present investigation was to investigate growth inhibitory activity of methanol-,ethanol-,and water-extracts from papaya fruit and leaves on MDA-MB-231(ER-/Her-2-),MCF-7(ER+/Her-2-),SK-BR-3(ER-/Her-2+)and MDA-MB-361,AU565(ER+/Her-2+)breast cancer ***:The anti-oxidation potential of papaya extracts was determined by assessing their total polyphenol content,total flavonoid content and by assaying their anti-oxidation *** effects on breast cancer cells proliferation were determined using a WST-1 ***:The seeds and leaves contained higher anti-oxidation potential than that of the skin and pulp *** data indicate that methanol-and ethanol-extracts of papaya leaves,skin,pulp,and seeds have no effect on any of the breast cancer cell lines,whereas water-extract of leaves and seeds caused low to modest cytotoxic effects only on ER-negative breast cancer cell ***:Our data suggest that bioactive compound in papaya leaves can be potentially used to develop anti-cancer agents for ER-negative breast cancer.

关键词： Breast cancer papaya leaves antioxidants polyphenols

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：