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Clinical application of a shape-preserving rapid corneal donor dehydrater

International Journal of Ophthalmology(English edition) 2022年第5期15卷 736-740页

作者： Yu Sun Xiao-Lin Qi Xiao Lin Xiao-Yu Zhang Li Gao Hua Gao Shandong First Medical University&Shandong Academy of Medical Sciences JinanShandong ProvinceChina Eye Hospital of Shandong First Medical University Shandong Eye Hospital JinanShandong ProvinceChina State Key Laboratory Cultivation Base Shandong Provincial Key Laboratory of OphthalmologyShandong Eye InstituteShandong First Medical University&Shandong Academy of Medical SciencesSchool of OphthalmologyShandong First Medical UniversityJinanShandong ProvinceChina Eye Hospital Affiliated to Shandong University of Chinese Medicine JinanShandong ProvinceChina

AIM:To describe the design and clinical application of a corneal donor dehydrator which can quickly dehydrate corneas and keep its original ***:The corneal donor material is placed on stainless steel beads with different diameters in the dehydrating box to make the cornea the same shape as the steel ***,the cornea is placed inside the dehydrater for rapid dehydrating using the internal cleaning and ventilation *** 83 eyes underwent deep anterior lamellar keratoplasty(DALK)using corneal donor tissue preserved with corneal dehydrater,and 60 patients(60 eyes)received DALK by the same surgeon using corneal donor tissue preserved with glycerol were included in the control *** best corrected visual acuity(BCVA),the thickness and transparency of the corneal buttons were ***:After the completion of dehydrating,all the donor corneas maintained a normal shape without any shrinkage or distortion,and the average intraoperative rehydration time was 43.3±12.1 s during *** mean BCVA of the dehydrater group was 0.30±0.18 at 1 wk and 0.32±0.16 at 1 mo,which were statistically better than that of the control group(P<0.001).The score of corneal buttons transparency were lower than that of the control group with statistical difference(P<0.001).The thickness of corneal buttons at 1 wk and at 1 mo in the dehydrater group was significantly better than that of the control group respectively(P<0.001).One week after operation,no corneal button turbidity or edema was observed in both ***:The dehydrater can quickly dehydrate the corneal material in a clean and airtight environment and maintain the original shape of the corneal donor during the dehydrating *** dehydrater is recommended for long-term high-quality preservation in areas where corneal materials cannot be used within a reasonable time period.

关键词： keratoplasty corneal donor dehydration organ culture storage eye bank

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