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orbital metastasis from anorectal carcinoma

Journal of Cancer metastasis and Treatment 2015年第1期1卷 104-105页

作者： Pavan Kumar Lachi Megha S.Uppin Monica Irukulla Kotiyala V.Jaganadha Rao Naidu1 Department of Radiation Oncology Nizam’s Institute of Medical SciencesHyderabad 500082TelanganaIndia Department of Pathology Nizam’s Institute of Medical SciencesHyderabad 500082TelanganaIndia.

Pulmonary and liver metastases are common sites of distant metastasis from the rectal *** to the head and neck region are uncommon from carcinoma of the rectum,and orbital metastases are extremely ***,we describe a 27-year-old female,who was diagnosed as a case of anorectal carcinoma in April *** underwent abdominoperineal resection followed by concurrent chemoradiotherapy and adjuvant chemotherapy with 5 fl uorouracil and leucovorin on *** January 2012,she presented with gradually increasing swelling over the left temporal region and left sided ***-needle aspiration and a cell block were *** was confi rmed *** radiotherapy to the left orbit at the dose of 3 Gy per fraction 10 fractions to a total dose of 30 Gy was given by *** patients with a history of rectal carcinoma,recent onset proptosis with temporal swelling,although rare,should raise suspicion of metastatic deposit.

关键词： Anorectal carcinoma distant metastasis orbital metastasis

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orbital metastases in Italy

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International Journal of Ophthalmology(English edition) 2015年第5期8卷 1018-1023页

作者： Patrizio Magliozzi Diego Strianese Paola Bonavolontà Mariantonia Ferrara Pasquale Ruggiero Raffaella Carandente Giulio Bonavolontà Fausto Tranfa Department of Neuroscience Odontostomatological and Reproductive SciencesUniversity of Naples Federico Ⅱ

AIMTo describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of *** chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of *** of 93 patients, 52 were females and 41 were males. Median age at diagnosis was 51y (range 1 to 88y). The patients have been divided into four groups on the basis of the year of diagnosis. The frequency of recorded cases had decreased significantly (Porbital imaging studies and open biopsy or fine needle aspiration biopsy (FNAB). Treatment included surgical excision, irradiation, chemotherapy, hormone therapy, or observation. Ninety-one percent of patients died of metastasis with an overall mean survival time (OMST) after the orbital diagnosis of ***, kidney and lung are the most frequent primary sites of cancer leading to an orbital metastasis. When the primary site is unknown, gastrointestinal tract should be carefully investigated. In the last decade a decrease in the frequency of orbital metastasis has been observed. Surgery provides a local palliation. Prognosis remains poor with a OMST of 13.5mo ranging from the 3mo in the lung cancer to 24mo in the kidney tumor.

关键词： orbital metastasis primary tumor survival time

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