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orbital liposarcoma: a retrospective, single-center study of thirteen patients

International Journal of Ophthalmology(English edition) 2023年第8期16卷 1293-1298页

作者： Ning Gao Xin Ge Cheng Pei Jian-Min Ma Ya-Guang Hu Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Beijing Ophthalmology and Visual Sciences Key Laboratory Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China

AIM:To explore the clinical and pathological characteristics of thirteen patients with orbital ***:The clinical history data of thirteen patients diagnosed as orbital liposarcoma at Beijing Tongren Hospital,from 2006 to 2021 were collected and *** data includes age,gender,affected orbital side,course of disease,status of disease(primary or recurrent),clinical manifestations,preoperative visual acuity,operative treatment,the relations between liposarcoma and surrounding tissue,longest diameter of liposarcoma,histological subtype,immunohistochemical indicators,follow-up treatment and ***:The initial symptoms are *** is the most frequent chief complaint and the others included vision loss,epiphora,diplopia,and eyelid palpable *** of imaging examination[computed tomography(CT)or magnetic resonance imaging(MRI)]showed orbital *** terms of treatment,10 patients received tumor resection,and the mean longest diameter of the tumor was 3.39±1.36 *** other 3 patients had optic nerve invaded,so they received orbital *** examination results confirmed the diagnose of liposarcoma for 13 *** patients displayed as myxoid type,and three patients in each type of dedifferentiated and welldifferentiated *** patient was verified as pleomorphic,which was a rare type of *** of the patients showed Vimentin positive,and most showed CD34 and S-100 ***,four patients showed smooth muscle actin *** thirteen patients were ***:orbital liposarcoma is a rare disease and it has no specific clinical *** diagnosis of liposarcoma should be considered when proptosis and orbital mass occurred in *** is recommended to perform pathological examination to achieve early detection and early treatment.

关键词： liposarcoma orbital tumor orbital mass proptosis

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Optical coherence tomography enhanced depth imaging of chorioretinal folds in patients with orbital tumors

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International Journal of Ophthalmology(English edition) 2023年第2期16卷 233-237页

作者： Zhi-Yu Peng Lu Gan Kang Xue Akrit Sodhi Xiao-Feng Ye Hui Ren Jiang Qian Department of Ophthalmology Eye and ENT Hospital of Fudan UniversityShanghai 200031China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031China Wilmer Eye Institute Johns Hopkins University School of MedicineBaltimoreMD 21287USA

AIM:To characterize spectral-domain optical coherence tomography(SD-OCT)features of chorioretinal folds in orbital mass imaged using enhanced depth imaging(EDI).METHODS:Prospective observational case-control study was conducted in 20 eyes of 20 patients,the uninvolved eye served as a *** the patients underwent clinical fundus photography,computed tomography,EDI SDOCT imaging before and after *** patients with cavernous hemangiomas underwent intratumoral injection of bleomycin A5;the remaining patients underwent tumor *** were followed 1 to 14mo following surgery(average follow up,5.8mo).RESULTS:Visual acuity prior to surgery ranged from 20/20 to 20/*** surgery,5 patients’visual acuity remained unchanged while the remaining 15 patients had a mean letter improvement of 10(range 4 to 26 letters).Photoreceptor inner/outer segment defects were found in 10 of 15 patients prior to *** surgical excision,photoreceptor inner/outer segment defects fully resolved in 8 of these 10 ***:Persistence of photoreceptor inner/outer segment defects caused by compression of the globe by an orbital mass can be associated with reduced visual *** findings suggest that photoreceptor inner/outer segment defects on EDI SD-OCT could be an indicator for immediate surgical excision of an orbital mass causing choroidal compression.

关键词： chorioretinal folds orbital mass enhanced depth imaging optical coherence tomography choroidal thickness inner/outer segment defects

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