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EFFICIENT FITTING RANGE FOR GLUCOSE MEASUREMENT WITH optical coherence TOMOGRAPHY

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Journal of Innovative optical Health Sciences 2009年第1期2卷 107-115页

作者： SHU FENG KEHONG YUAN DATIAN YE Graduate School at Shenzhen&Department of Biomedical Engineering Tsinghua University China

Studies of non-invasive glucose measurement with optical coherence tomography(OCT)in tissue-simulating phantoms and biological tissues show that glucose has an effect on the OCT signal *** an efficient fitting range to calculate the OCT signal slope is important because it helps to improve the precision of glucose *** this paper,we study the problem in two ways:(1)scattering-induced change of OCT signal slope versus depth in intralipid suspensions with different concentrations based on Monte Carlo(MC)simulations and experiments and(2)efficient fitting range for glucose measurement in 3%and 10%*** results show that the OCT signal slope expresses a contrary change with scattering coefficient below a certain depth in high intralipid concentrations,so that there is an effective fitting *** an efficient fitting range from 100μm to the effective fitting depth,the precision of glucose measurement can be 4.4mM for 10%intralipid and 2.2mM for 3%intralipid.

关键词： optical coherence tomography noninvasive glucose measurement multiple scattered photons

Diagnosis and management of hepatic artery in-stent restenosis after liver transplantation by optical coherence tomography:A case report

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World Journal of Hepatology 2020年第7期12卷 399-405页

作者： Francisco Leonardo Galastri Guilherme Moratti Gilberto Breno Boueri Affonso Leonardo Guedes Moreira Valle Priscila Mina Falsarella Adriano Mendes Caixeta Camila Antunes Lima Marcela Juliano Silva Lucas Lembrança Pinheiro Conrado Dias Pacheco Annicchino Baptistella Márcio Dias de Almeida Rodrigo Gobbo Garcia Nelson Wolosker Felipe Nasser Hospital Israelita Albert Einstein Department of Interventional RadiologySão Paulo 05652900Brazil Hospital Israelita Albert Einstein Department of Interventional CardiologySão Paulo 0562900Brazil Hospital Israelita Albert Einstein Department of Liver TransplantSão Paulo 05652900Brazil Hospital Israelita Albert Einstein Department of Vascular SurgerySão Paulo 05652-000Brazil

BACKGROUNDPercutaneous transluminal angioplasty and stenting represent an effectivetreatment for hepatic artery stenosis after liver transplantation. In the first yearafter stenting, approximately 22% of patients experience in-stent restenosis,increasing the risk of artery thrombosis and related complications, and 50%experience liver failure. Although angiography is an important tool for diagnosisand the planning of therapeutic interventions, it may raise doubts, especially insmall-diameter arteries, and it provides low resolution rates compared withnewer intravascular imaging methods, such as optical coherence tomography(OCT).CASE SUMMARYA 64-year-old male developed hepatic artery stenosis one year after orthotropicliver transplantation and was successfully treated with percutaneous transluminalangioplasty with stenting. Five months later, the Doppler ultrasound resultsindicated restenosis. Visceral arteriography confirmed hepatic artery tortuositybut was doubtful for significant in-stent restenosis (ISR) and intrahepatic flowreduction. To confirm ISR, identify the etiology and guide treatment, OCT wasperformed. OCT showed severe stenosis due to four mechanisms: Focal andpartial stent fracture, late stent malapposition, in-stent neointimal hyperplasia,and *** diagnostic methods can be useful in evaluating cases in which initialangiography results are not sufficient to provide a proper diagnosis of significantstenosis, especially with regard to ISR. A wide range of diagnoses are provided byOCT, resulting in different treatment options. Interventional radiologists shouldconsider intravascular diagnostic methods as additional tools for evaluatingpatients when visceral angiography results are unclear.

关键词： Liver transplantation Hepatic artery restenosis Tomography optical coherence Case report Endovascular procedures Angiography

Measurement of optical coherence structures of random optical fields using generalized Arago spot experiment

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Opto-Electronic Science 2023年第2期2卷 27-35页

作者： Xin Liu Qian Chen Jun Zeng Yangjian Cai Chunhao Liang Shandong Provincial Engineering and Technical Center of Light Manipulation&Shandong Provincial Key Laboratory of Optics and Photonic Devices School of Physics and ElectronicsShandong Normal UniversityJinan 250014China Collaborative Innovation Center of Light Manipulations and Applications Shandong Normal UniversityJinan 250358China

The optical coherence structures of random optical fields can determine beam propagation behavior,light–matter interactions,*** performance makes a light beam robust against turbulence,scattering,and ***,we proposed optical coherence encryption and robust far-field optical imaging *** related applications place a high demand on precision in the experimental measurements of complex optical coherence structures,including their real and imaginary *** studies on these measurements have mainly adopted theoretical mathematical approximations,limited to Gaussian statistic involving speckle statistic(time-consuming),or used complicated and delicate optical systems in the *** this study,we provide:a robust,convenient,and fast protocol to measure the optical coherence structures of random optical fields via generalized Arago(or Poisson)spot experiments with rigorous mathematical *** proposal only requires to capture the intensity thrice,and is applicable to any optical coherence structures,regardless of their type or optical *** theoretical and experimental results demonstrated that the real and imaginary parts of the structures could be simultaneously recovered with high *** believe that such a protocol can be widely employed in phase measurement,optical imaging,and image transfer.

关键词： optical coherence statistical optics Arago spot optical encryption optical imaging

Effects of two different doses of intravitreal bevacizumab on subfoveal choroidal thickness and retinal vessel diameter in branch retinal vein occlusion

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International Journal of Ophthalmology(English edition) 2016年第7期9卷 999-1005页

作者： Jongyeop Park Seungwoo Lee Yengwoo Son Department of Ophthalmology Dongguk University Gyeongju Hospital Gyeongju-si Gyeongsangbuk-do 780-350 Korea

AIM： To investigate the effects of two different doses of intravitreal bevacizumab on subfoveal choroidal thickness （SFChT） and retinal vessel diameter in patients with branch retinal vein occlusion. METHODS： An interventional, restrospective study of 41 eyes of 41 patients who had completed 12mo of follow-up, divided into group 1 （1.25 mg of bevacizumab, 21 eyes of 21 patients） and group 2 （2.5 mg of bevacizumab, 20 eyes of 21 patients）. Complete ophthalmic examination, fluorescein angiography, enhanced depth imaging optical coherence tomography and measurement of retinal vessel diameter with IVAN software were performed at baseline and follow-up. RESULTS： The SFChT changed from 279.1 （165-431） μm at baseline to 277.0 （149-413） μm at 12mo in group 1 （P= 0.086）, and from 301.4 （212-483） μm to 300.3 （199-514） μm in group 2 （P=0.076）. The central retinal arteriolar equivalent （CRAE） changed from 128.8 ±11.2 μm at baseline to 134.5±8.4 μm at 12mo in group 1, and from 134.6±9.0 μm to 131.4±12.7 μm in group 2 （P =0.767）. The central retinal venular equivalent （CRVE） changed from 204.1±24.4 μm at baseline to 196.3±28.2 μm at 12mo in group 1, and from 205.8±16.3 μm to 194.8±18.2 μm in group 2 （P=0.019）. The mean central macular thickness （P〈0.05） and average best-corrected visual acuity （BCVA; P〈0.05） improved in both groups CONCLUSION： Changes in the SFChT are not statistically significant and not different according to the doses of bevacizumab. The CRAE did not show significant change, however, the CRVE showed significant decrease regardless of the dose.

关键词： bevacizumab retinal vein occlusion choroids tomography optical coherence intravitreal injections retinal vessels

Clinical and multimodal imaging features of acute macular neuroretinopathy lesions following recent SARS-CoV-2 infection

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International Journal of Ophthalmology(English edition) 2023年第5期16卷 755-761页

作者： Yang-Chen Liu Bin Wu Yan Wang Song Chen Tianjin Eye Hospital Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye InstituteNankai University Affiliated Eye HospitalTianjin 300000China Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300070China Nankai Eye Institute Nankai UniversityTianjin 300071China

AIM:To describe the clinical characteristics of eyes using multimodal imaging features with acute macular neuroretinopathy(AMN)lesions following severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)***:Retrospective case series *** December 18,2022 to February 14,2023,previously healthy cases within 1-week infection with SARS-CoV-2 and examined at Tianjin Eye Hospital to confirm the diagnosis of AMN were included in the *** 5 males and 9 females[mean age:29.93±10.32(16-49)y]were presented for reduced vision,with or without blurred *** patients underwent best corrected visual acuity(BCVA),intraocular pressure,slit lamp microscopy,indirect ***,multimodal imagings fundus photography(45°or 200°field of view)was performed in 7 cases(14 eyes).Near infrared(NIR)fundus photography was performed in 9 cases(18 eyes),optical coherence tomography(OCT)in 5 cases(10 eyes),optical coherence tomography angiography(OCTA)in 9 cases(18 eyes),and fundus fluorescence angiography(FFA)in 3 cases(6 eyes).Visual field was performed in 1 case(2 eyes).RESULTS:Multimodal imaging findings data from 14 patients with AMN were *** eyes demonstrated different extent hyperreflective lesions at the level of the inner nuclear layer and/or outer plexus layer on OCT or *** photography(45°or 200°field of view)showed irregular hypo-reflective lesion around the fovea in 7 cases(14 eyes).OCTA demonstrated that the superficial retinal capillary plexus(SCP)vascular density,deep capillary plexus(DCP)vascular density and choriocapillaris(CC)vascular density was reduced in 9 case(18 eyes).Among the follow-up cases(2 cases),vascular density increased in 1 case with elevated BCVA;another case has vascular density decrease in one eye and basically unchanged in other *** face images of the ellipsoidal zone and interdigitation zone injury showed a low wedge-shaped reflection contour *** image mainly show the absence of th

关键词： SARS-CoV-2 infection tomography optical coherence acute macular neuroretinopathy multimodal imaging features

Effect of phosphor sedimentation on photochromic properties of a warm white light-emitting diode

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Journal of Semiconductors 2018年第12期39卷 90-94页

作者： Yunyi Zhuang Yong Wang Liping Wang Zhanguo Li Wenbo Li Lei Yang Jun Zou National Key Laboratory on High Power Semiconductor Lasers Changchun University of Science and TechnologyChangchun 130022China Zhejiang Emitting Optoelectronic Technology Co. Ltd.Jiaxing 314100China Shanghai Institute of Technology Shanghai 201418China

In the process of producing a white light emitting diode, the consistency of the optical coherence and stability of the photochromic properties is a crucial index for measuring the quality of the product. Phosphor sedimentation is a significant factor affecting optical coherence, thus, in this paper, seven sets of control experiments were set up with the phenomenon of the phosphor precipitation at time intervals 0, 2, 5, 10, 20, 30, and 40 *** color coordination concentration and optical properties were also tested. The results indicate that phosphor sedimentation occurs between 0 and 20 min, during which the color coordinate placement is concentrated, the central coordinates are(x = 0.4432 ± 0.004, y = 0.4052±0.002); the quality was verified because the supply demand chain management(SDCM) was no greater than 7. Later, between 30 and 40 min, the central coordinates are(x = 0.4366 ± 0.003, y = 0.4012 ± 0.003), which had an SDCM value higher than 7, and had a more discrete color placement; it does not meet the requirements of the national standard GBT24823-2016 general lighting LED module performance.

关键词： optical coherence phosphor color coordinates sedimentation concentration

Optimizing illumination's complex coherence state for overcoming Rayleigh's resolution limit

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Chinese Optics Letters 2021年第5期19卷 65-70页

作者： Chunhao Liang Yashar E.Monfared Xin Liu Baoxin Qi Fei Wang Olga Korotkova Yangjian Cai Shandong Provincial Engineering and Technical Center of Light Manipulations&Shandong Provincial Key Laboratory of Optics and Photonic Device School of Physics and ElectronicsShandong Normal UniversityJinan 250014China Department of Chemistry Dalhousie UniversityHalifaxNS B3H 4R2Canada School of Physical Science and Technology&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou 215006China Department of Physics University of MiamiCoral GablesFlorida 33146USA

We suggest tailoring of the illumination's complex degree of coherence for imaging specific two-and three-point objects with resolution far exceeding the Rayleigh *** first derive a formula for the image intensity via the pseudo-mode decomposition and the fast Fourier transform valid for any partially coherent illumination(Schell-like,non-uniformly correlated,twisted)and then show how it can be used for numerical image ***,for Schell-model sources,we show the improvement of the two-and three-point resolution to 20%and 40%of the classic Rayleigh distance,respectively.

关键词： optical coherence imaging light manipulation

Propagation of partially polarized Gaussian Schell-model beams through aligned and misaligned optical systems

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Chinese Physics B 2005年第1期14卷 128-132页

作者：戈迪蔡阳健林强 InstituteofOptics DepartmentofPhysicsZhejiangUniversityHangzhou310027China

By use of a tensor method, the transform formulae for the beam coherence-polarization matrix of the partially polarized Gaussian Schell-model (GSM) beams through aligned and misaligned optical systems are derived. As an example, the propagation properties of the partially polarized GSM beam passing through a misaligned thin lens are illustrated numerically and discussed in detail. The derived formulae provide a convenient way to study the propagation properties of the partially polarized GSM beams through aligned and misaligned optical systems.

关键词： partially polarized beam physical optics optical coherence

An Overview of the Retinal and Choroidal Changes and Their Influencing Factors after Treatment of Amblyopia

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Open Journal of Ophthalmology 2022年第2期12卷 158-169页

作者： Liuyi Jing Jing Shi Xiaobo Tan Jie Yang Xingyu Chen Department of Ophthalmology Affiliated Hospital of Chengde Medical College Chengde China

Purpose of Review: Amblyopia is the reduction in the best-corrected visual acuity of one or both eyes and the most common cause of the loss of vision in children. Previously, amblyopia was thought to have no organic lesions. However, the latest “Amblyopia Preferred Practice Pattern” of 2017 points out that in amblyopia, the eye structure is abnormal with a defective eye function, with few differences from the structure of contralateral non-amblyopic eyes. With the development of optical coherence tomography and optical coherence tomography angiography, it has been observed that even the ocular structure of amblyopic eyes is different from that of normal eyes. Here, we review studies investigating the changes in amblyopic eye structure upon treatment. Review Findings: The pathogenesis of amblyopia is controversial and not well-understood. The retina, choroid, and blood vessels of amblyopic eyes are different from those of normal eyes. Further, the various types of amblyopia are affected differently upon treatment. Because of the scarcity of studies and long-term follow-up observations, the underlying reason for such differences is unclear. Age, gender, and axial length are the influencing factors of the retina and choroid, and the relationship of these factors with amblyopia needs to be investigated further. Conclusion: This review will help us understand the pathogenesis of amblyopia and the underlying mechanism for the changes that occur upon treatment. Further, knowledge of the changes in ocular structure summarized here will be helpful for the diagnosis and treatment of amblyopia.

关键词： Amblyopia Children Retina Choroid optical coherence