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ocular syphilis:a case series of four patients and a review of the literature

Annals of Eye Science 2024年第2期9卷 62-70页

作者： Madeline Beckman Lana M.Rifkin Department of Ophthalmology and Visual Sciences The Ohio State UniversityColumbusOHUSA Ophthalmic Consultants of Boston Uveitis ServiceBostonMAUSA

Background:The incidence of syphilis has been increasing in the United States over the last two decades,with a more recent increase among *** syphilis is an uncommon but important complication of syphilis,most often presenting as posterior or panuveitis in late or latent syphilis of unknown *** ocular syphilis may lead to permanent vision loss,underscoring the importance of appropriate evaluation and treatment of ocular *** Description:In a retrospective,non-contiguous case series,we highlight four patients diagnosed and treated with ocular syphilis at a single *** presentations of ocular syphilis are illustrated:anterior and intermediate uveitis,optic neuritis,posterior uveitis,and *** patients initially presented with a decreased visual acuity(VA).One patient had a previous diagnosis of human immunodeficiency virus(HIV).Three patients were treated with intravenous(IV)penicillin and one patient with IV *** had a return to their baseline VA after their course of ***:syphilis may go undetected without a high index of clinical suspicion due to its nonspecific *** patients with ocular inflammation should have syphilis testing as a part of their infectious workup with both treponemal and non-treponemal *** diagnosed with syphilis and are not known to be HIV-negative should undergo testing for HIV due to the high rate of *** diagnosis and prompt treatment after onset of symptoms may contribute to a more favorable prognosis for ocular syphilis.

关键词： ocular syphilis uveitis choroiditis intermediate uveitis case series

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ocular syphilis resurgence in an urban underserved community in the United States

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International Journal of Ophthalmology(English edition) 2022年第8期15卷 1357-1362页

作者： Emily K.Tam Alexander Port Diana Martin Gabrielle Fridman Steven Ness Nicole H.Siegel Department of Ophthalmology Boston Medical CenterBostonMA 02118USA

AIM:To evaluate the clinical characteristics,demographics,and visual outcomes of patients with ocular syphilis at an urban hospital to increase awareness and assist in earlier diagnosis and treatment of the resurgent ***:A retrospective chart review was performed on patients with ICD-9 and ICD-10 diagnosis codes correlating with syphilis or syphilis-related ocular diseases between 2010 and *** evaluated included age,gender,race,vision,ocular findings,human immunodeficiency virus(HIV)status and men who have sex with men status,recreational drug and alcohol ***:ocular syphilis was diagnosed in 40 patients(53 eyes)of a total of 229 patients who tested positive for syphilis via serum and/or cerebrospinal fluid treponemal testing from *** patients with ocular syphilis,most patients were males,aged 45 or above and Black,and had no diagnosed HIV *** 50%patients had 20/40 vision or *** 50%had nongranulomatous anterior uveitis as their initial presentation,and 49%of patients had involvement of the posterior *** glaucoma(5.7%),papillitis(7.5%),vasculitis(5.7%),and retinal detachment(5.7%)were rarer presentations of the disease and were associated with a poorer visual ***:Given the increased prevalence and protean manifestations of syphilis,early diagnosis and treatment are *** studies on ocular syphilis are warranted to understand this resurging disease.

关键词： ocular syphilis neurosyphilis uveitis surveillance treponema pallidum

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ocular syphilis: resurgence of an old disease in modern Malaysian society

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International Journal of Ophthalmology(English edition) 2018年第9期11卷 1573-1576页

作者： Mushawiahti Mustapha Zakaria Abdollah Amin Ahem Hazlita Mohd Isa Mae-Lynn Catherine Bastion Norshamsiah Md Din Department of Ophthalmology Pusat Perubatan Universiti

Dear Editor,syphilis is a spirochaetal bacterial sexually transmitted disease（STD） caused by Treponema pallidum. Outbreaks of syphilis have been described in Western communities, especially in men who have sex with men（MSM） and people infected with human immunodeficiency virus（HIV）^（[1]）. Reports of the condition from Asian countries remains limited.

关键词： ocular syphilis OS OD HIV MSM resurgence of an old disease in modern Malaysian society

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