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Understanding the epidemiology and outcomes of out-of-hospital cardiac arrest in the former Union of Soviet Socialist Republics:Observations from the Crimean peninsula

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World Journal of Emergency Medicine 2022年第1期13卷 67-68页

作者： Alexei Birkun Department of Anesthesiology Resuscitation and Emergency MedicineMedical Academy named after S.I.Georgievsky of V.I.Vernadsky Crimean Federal UniversitySimferopol 295051Russian Federation

Out-of-hospital cardiac arrest(OHCA)is widely recognized as a global health issue.However,little is known about OHCA epidemiology in the former Union of Soviet Socialist Republics(USSR)territories.[1,2]The15 post-Soviet states occupy nearly one-sixth of the land surface of the earth,and the total population exceeds 292 million people.

关键词： occupy Republic cardiac

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一种双极产氢电解系统

Science Bulletin 2022年第17期67卷 1713-1715页

作者：杨明王双印邹雨芹 State Key Laboratory of Chem/Bio-Sensing and Chemometrics Provincial Hunan Key Laboratory for Graphene Materials and DevicesCollege of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Shenzhen Institute of Hunan University Shenzhen 518057China

Hydrogen,a prospective green fuel with the advantages of high calorific value and no byproducts,is a main focus in the new energy area[1].Many mature ways to produce Hinclude reforming fossil fuels and water electrolysis.Reforming fossil fuels occupy the vast majority of hydrogen production because of their low cost.However,it is unsustainable and polluting[2].

关键词： reforming occupy 电解系统

全球清洁能源快速增长引发对土地资源占用的担忧

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Science Bulletin 2023年第6期68卷 571-573,M0003页

作者：张宁段华波杨家宽 Leibniz Institute of Ecological Urban and Regional Development(IOER) Dresden 01217Germany School of Environmental Science&Engineering Huazhong University of Science and Technology(HUST)Wuhan 430074China

Most countries in the world have joined the race for carbon neutrality, to meet the goals of the 2015 Paris Agreement, leading to a boom in the clean-energy sector. However, the construction of clean-energy infrastructure can disproportionately occupy limited productive soil and natural land resources, compared to conventional energy plants (Fig. 1). Thus, comprehending the land footprint resulting from the proliferation of clean-energy systems is now imperative, to better anticipate and manage the energy industry, and specifically to quantify the land-use trade-offs of the energy transition in a global context.

关键词： occupy neutral goals

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

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四川生理科学杂志 2022年第9期44卷 1639-1639页

作者： Nouf N Laqtom Department of Chemical Engineering Stanford University Stanford CA USA Department of Genetics Stanford University Stanford CA USA The Institute for Chemistry Engineering & Medicine for Human Health (ChEM-H) Stanford University Stanford CA USA Department of Biochemistry Stanford University School of Medicine Stanford CA USA Department of Biology Massachusetts Institute of Technology Cambridge MA USA Koch Institute for Integrative Cancer Research Cambridge MA USA Whitehead Institute for Biomedical Research Cambridge MA USA Leibniz Institute on Aging—Fritz Lipmann Institute Jena Germany Walther Straub Institute of Pharmacology and Toxicology Faculty of Medicine Ludwig-Maximilians-Universität Munich Germany Division of Translational Medicine Eunice Kennedy Shriver National Institute of Child Health and Human Development NIH Bethesda MD USA

Lysosomes have many roles,including degrading macromolecules and signalling to the nucleus1.Lysosomal dysfunction occurs in various human conditions,such as common neurodegenerative diseases and monogenic lysosomal storage disorders(LSDs)2-4.For most LSDs,the causal genes have been identified but,in some,the function of the implicated gene is unknown,in part because lysosomes occupy a small fraction of the cellular volume so that changes in lysosomal contents are difficult to detect.Here we develop the LysoTag mouse for the tissue-specific isolation of intact lysosomes that are compatible with the multimodal profiling of their contents.We used the LysoTag mouse to study CLN3,a lysosomal transmembrane protein with an unknown function.In children,the loss of CLN3 causes juvenile neuronal ceroid lipofuscinosis(Batten disease),a lethal neurodegenerative LSD.Untargeted metabolite profiling of lysosomes from the brains of mice lacking CLN3 revealed a massive accumulation of glycerophosphodiesters(GPDs)-the end products of glycerophospholipid catabolism.GPDs also accumulate in the lysosomes of CLN3-deficient cultured cells and we show that CLN3 is required for their lysosomal egress.Loss of CLN3 also disrupts glycerophospholipid catabolism in the lysosome.Finally,we found elevated levels of glycerophosphoinositol in the cerebrospinal fluid of patients with Batten disease,suggesting the potential use of glycerophosphoinositol as a disease biomarker.Our results show that CLN3 is required for the lysosomal clearance of GPDs and reveal Batten disease as a neurodegenerative LSD with a defect in glycerophospholipid metabolism.

关键词： CLN3 elevated occupy

First Results from the Underground Nuclear Reaction Experiments in JUNA

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Chinese Physics Letters 2023年第6期40卷 13-15页

作者：柳卫平 College of Science Southern University of Science and TechnologyShenzhen 518055China China Institute of Atomic Energy Beijing 102413China

The China Jinping Underground Laboratory phaseⅡ[1](CJPL-Ⅱ)is the expansion project following the success of CJPL-I.A temporary usage in the year 2020–2021 enabled the Underground Nuclear Astrophysics Experiment in China(JUNA)phase I experiments presented here.Once commissioned in 2023,CJPL-Ⅱwill occupy a much larger underground space(300000 m^(3)in volume)for conducting experiments and is planned to house CDEX-Ⅱ。

关键词： occupy conducting phase

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COLLECTING TRENDS

The World of Chinese 2022年第2期 38-40页

作者：席宁忆不详

Young,middle class buyers are bending China’s art market to their own tastes Every summer,the fifth floor at the five-star Peninsula Hotel in the heart of Beijing transforms for a weekendlong extravaganza.A few dozen suites open their doors to visitors who walk in to discover colorful diptychs above headboards,abstract sculptures on window sills,glittering jewelry in drawers,and ceramic figurines by bathtubs,all curated by galleries who temporarily occupy these suites as their booths at Art Fair in Hotel(AFIH).

关键词： occupy ceramic floor

Performance of Quantization Factor in H.261 Video Coding

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High Technology Letters 2001年第3期7卷 37-41页

作者：于波 Communication Research Centre Harbin Institute of Technology Harbin 150001 China

The quantizaion factor through buffer pure occupy algorithm is provided. Through the simulation, firstly the relationship between quantization factor and compression ratio is analyzed, secondly the PSNR of the image with the quantization factor is discussed, and finally the control to the output rate of the coder by adjusting the value of quantization factor is studied.

关键词： H.261 Quantization factor PSNR Buffer pure occupy control

Is Italy's textile economy shrinking by half due to ongoing Russia-Ukraine conflict?

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China Textile 2022年第3期 10-11页

作者： Zhao Xinhua 不详

As a textile power,Italy’s fashion industry is highly developed,and the production capacity,export and market share of Italy’s T&C sector occupy an important position in Europe’s and even the world’s T&C sector,"M... 详细信息

关键词： occupy sector Russia

Design of Protein Segments and Peptides for Binding to Protein Targets

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BioDesign Research 2022年第1期2022卷 312-336页

作者： Suchetana Gupta Noora Azadvari Parisa Hosseinzadeh Knight Campus Center for Accelerating Scientific Impact University of OregonEugene OR 97403USA

Recent years have witnessed a rise in methods for accurate prediction of structure and design of novel functional proteins. Designof functional protein fragments and peptides occupy a small, albeit unique, space within the general field of protein design. Whilethe smaller size of these peptides allows for more exhaustive computational methods, flexibility in their structure and sparsity ofdata compared to proteins, as well as presence of noncanonical building blocks, add additional challenges to their design. Thisreview summarizes the current advances in the design of protein fragments and peptides for binding to targets and discussesthe challenges in the field, with an eye toward future directions.

关键词： directions occupy canonical