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novel Primate Bocaparvovirus Species 3 Identified in Wild Macaca Mulatta in China

Virologica Sinica 2020年第1期35卷 34-42页

作者： Yuanyun Ao Zhaojun Duan Chinese Center for Disease Control and Prevention National Institute for Viral Disease Control and PreventionBeijingChina

Primate bocaparvovirus(BOV) is a possible cause of respiratory disorders and gastroenteritis in humans. However, the diversity and evolution of these viruses remain largely unknown, despite the identification of a growing number of BOVs in non-human primates(NHPs). Here, we report the identification of a novel BOV(provisionally named Macaca mulatta bocaparvovirus [MmBOV]) in the feces of wild Macaca mulatta in China by viral metagenomic analysis. Seven of 400 fecal samples from Macaca mulatta were positive for MmBOV. An almost complete genome sequence of 4,831 nucleotides was obtained, which had genomic organization and protein motifs similar to human bocaviruses(HOBVs), and shared characteristically low G/C content and weak codon usage bias. Sequence analyses of NS1, NP1, and VP1 revealed that Mm BOV was most closely related to HBOV4 of Primate bocaparvovirus 2(approximately 68.4%/70.6%, 73.3%/67.6%, and 70.4%/73.1% nucleotide/amino acid identities, respectively). Additionally, phylogenetic analysis revealed that Mm BOV formed an independent peripheral branch, but clustered closely with those of the Primate bocaparvovirus species in the BOV genus(particularly HBOV4). These data strongly suggest that HBOV4 originated from NHP bocaparvoviruses around 200–300 years ago, and that NHPs may act as HBOV reservoirs. Following the International Committee of Taxonomy for Viruses guidelines, we propose Mm BOV as a new species(tentatively named Primate bocaparvovirus 3) in the genus Bocaparvovirus, which is the first report of a novel species of primate BOV. Our data facilitate future research on the genetic diversity and evolution of primate bocaparvoviruses and highlight the importance of bocaparvovirus surveys in wild NHPs.

关键词： Primate bocaparvovirus(BOV) novel species Macaca mulatta Sequence analysis Phylogenetic analysis

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novel　Highly　Branched　Polyester　Nanoparticles(I)──Light-Scattering　Characterization

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Chemical Research in Chinese Universities 1998年第1期14卷 70-75页

作者： Ma, RJ Wu, Q Jilin Univ Inst Polymer Changchun 130023 Peoples R China Chinese Univ Hong Kong Dept Chem Shatin NT Peoples R China

ＮｏｖｅｌＨｉｇｈｌｙＢｒａｎｃｈｅｄＰｏｌｙｅｓｔｅｒＮａｎｏｐａｒｔｉｃｌｅｓ（Ｉ）──Ｌｉｇｈｔ－ＳｃａｔｔｅｒｉｎｇＣｈａｒａｃｔｅｒｉｚａｔｉｏｎＭＡＲｏｎｇ－Ｊｉｕ（ＰｏｌｙｍｅｒＩｎｓｔｉｔｕｔｅ，Ｊｉ... 详细信息

ＮｏｖｅｌＨｉｇｈｌｙＢｒａｎｃｈｅｄＰｏｌｙｅｓｔｅｒＮａｎｏｐａｒｔｉｃｌｅｓ（Ｉ）──Ｌｉｇｈｔ－ＳｃａｔｔｅｒｉｎｇＣｈａｒａｃｔｅｒｉｚａｔｉｏｎＭＡＲｏｎｇ－Ｊｉｕ（ＰｏｌｙｍｅｒＩｎｓｔｉｔｕｔｅ，ＪｉｌｉｎＵｎｉｖｅｒｓｉｔｙ，Ｃｈａ...

关键词： Branched Nanoparticles novel Polyester Highly

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novel Membranes Regenerated from Blends of Cellulose/Gluten Using Ethylenediamine/Potassium Thiocyanate Solvent System

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Journal of Renewable Materials 2019年第1期7卷 41-55页

作者： Yang Yu Ramiz Boy Richard Kotek Fiber and Polymer Science Program College of TextilesNorth Carolina State UniversityRaleighNC 27606USA Department Textile Engineering Çorlu Faculty of EngineeringTekirdağNamık Kemal UniversityTekirdağ59860TURKEY

Current industrial methods for dissolution of cellulose in making regenerated cellulose products are relatively expensive,toxic and dangerous and have environmental problems coming with the hazard chemical *** solve these problems,a novel ethylenediamine and potassium thiocyanate(ED/KSCN)solvent system was developed,that is economical,ecofriendly,and highly *** ED/KSCN solvent system was proven to be a suitable solvent for fabricating cellulose(blended with other polymers)*** this study,gluten was used to develop nonporous membranes with *** method of casting these membranes provided better ones than the former researchers’*** composite membranes’physical and mechanical properties were studied by analysis of morphology,viscosity,crystallinity,thermal behaviors,tensile properties and water absorption of *** showed that membranes are nonporous,uniform,strong,flexible,ecofriendly and *** and physical properties were influenced by the ratio of cellulose/*** blending 40% gluten,the tensile strength of cellulose membrane dropped to 15.89 MPa from 35.11 ***,its elongation at break increased from 35.3% to 57.02% accordingly.

关键词： Cellulose gluten blended film novel ED/KSCN solvent physical and mechanical properties

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novel miRNA, miR-sc14, promotes Schwann cell proliferation and migration

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Neural Regeneration Research 2019年第9期14卷 1651-1656页

作者： Xi-Meng Ji Shan-Shan Wang Xiao-Dong Cai Xing-Hui Wang Qian-Yan Liu Pan Wang Zhang-Chun Cheng Tian-Mei Qian Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education Co-innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina Nonnasality Clinical Medicine Nanjing Medical UniversityNanjingJiangsu ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

MicroRNAs refer to a class of endogenous,short non-coding RNAs that mediate numerous biological *** regulate various physiological and pathological activities of peripheral nerves,including peripheral nerve repair and ***,using a rat sciatic nerve injury model,we identified many functionally annotated novel microRNAs,including ***,we used real-time reverse transcription-polymerase chain reaction to examine miR-sc14 expression in rat sciatic nerve *** results show that miRsc14 is noticeably altered following sciatic nerve injury,being up-regulated at 1 day and diminished at 7 *** and transwell chamber assay results showed that miR-sc14 mimic promoted proliferation and migration of Schwann cells,while miR-sc14 inhiThe study was approved by the Jiangsu Provincial Laboratory Animal Management Committee,China on March 4,2015(approval No.20150304-004).bitor suppressed their proliferation and ***,bioinformatic analysis examined potential target genes of miR-sc14,and found that fibroblast growth factor receptor 2 might be a potential target ***,our results show changes of miR-sc14 expression in the sciatic nerve of rats at different time points after nerve ***,up-regulation of miR-sc14 promoted proliferation and migration of Schwann ***,miR-sc14 may be an intervention target to promote repair of peripheral nerve *** study was approved by the Jiangsu Provincial Laboratory Animal Management Committee,China on March 4,2015(approval No.20150304-004).

关键词： nerve regeneration novel microRNAs miR-sc14 peripheral nerve injury cell proliferation cell migration Schwann cells fibroblast growth factor receptor 2 biological functions peripheral nerve regeneration regulatory mechanisms neural regeneration

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Searching for novel materials via 4f chemistry

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Journal of Rare Earths 2019年第1期37卷 1-10,M0002页

作者： Congting Sun Keyan Li Dongfeng Xue State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of Sciences State Key Laboratory of Fine Chemicals PSU-DUT Joint Center for Energy ResearchSchool of Chemical EngineeringDalian University of Technology

4f chemistry studies the chemical bonding characteristics of fifteen lanthanide (Ln) elements in the periodic table and their wide applications in materials sciences and engineering, which forms the scientific fundamentals ofⅥperiodic elements in the periodic table of elements. Orbital hybridization modes of Ln elements clarify their chemical bonding nature in all reaction systems. Wide coordination number (CN) option, ranging from 2 to 16, is the reason why Ln elements are the treasure of new materials, therefore, searching for novel materials may be well carried out via the rational design of coordination environment of central Ln cations to stabilize their variable energy states. Balance utilization of Ln elements is dependent on their coordination architecture in the crystallographic frame, Ln elements can be replaced by non-Ln elements when CN <10, and when CN≥10 expensive Ln elements can be replaced by those cheaper ones.

关键词： 4f chemistry Chemical bonding Electronegativity Orbital hybridization novel structure Balance utilization of lanthanide elements

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Superconducting Single-Layer T-Graphene and novel Synthesis Routes

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Chinese Physics Letters 2019年第9期36卷 46-63页

作者： Qinyan Gu Dingyu Xing Jian Sun National Laboratory of Solid State Microstructures School of Physics and Collaborative Innovation Center of Ad vanced MicrostructuresNanjing UniversityNanjing 210093

Single-layer superconductors are ideal materials for fabricating superconducting nano ***,up to date,very few single-layer elemental superconductors have been predicted and especially no one has been successfully synthesized ***,using crystal structure search techniques and ab initio calculations,we predict that a single-layer planar carbon sheet with 4-and 8-membered rings called T-graphene is a new intrinsic elemental superconductor with superconducting critical temperature(Tc)up to around 20.8 *** importantly,we propose a synthesis route to obtain such a single-layer T-graphene,that is,a T-graphene potassium intercalation compound(C4 K with P4/mmm symmetry)is firstly synthesized at high pressure(>11.5 GPa)and then quenched to ambient condition;and finally,the single-layer T-graphene can be either exfoliated using the electrochemical method from the bulk C4 K,or peeled off from bulk T-graphite C4,where C4 can be obtained from C4 K by evaporating the K ***,we find that the calculated Tc of C4 K is about 30.4 K at 0 GPa,which sets a new record for layered carbon-based *** present findings add a new class of carbon-based *** particular,once the single-layer T-graphene is synthesized,it can pave the way for fabricating superconducting devices together with other 2 D materials using the layer-by-layer growth techniques.

关键词： red Superconducting Single-Layer T-Graphene and novel Synthesis Routes Graphene

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Electron beam irradiation on novel coronavirus(COVID-19):A Monte-Carlo simulation

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Chinese Physics B 2020年第4期29卷 556-562页

作者： Guobao Feng Lu Liu Wanzhao Cui Fang Wang National Key Laboratory of Science and Technology on Space Microwave China Academy of Space TechnologyXi'an 710000China School of Computer Science and Engineering Xi'an University of TechnologyXi'an 710048China Key Laboratory for Physical Electronics and Devices of the Ministry of Education Xi'an Jiaotong UniversityXi'an 710049China

The novel coronavirus pneumonia triggered by COVID-19 is now raging the whole *** a rapid and reliable killing COVID-19 method in industry,electron beam irradiation can interact with virus molecules and destroy their *** the unexpected appearance and quickly spreading of the virus,it is urgently necessary to figure out the mechanism of electron beam irradiation on *** this study,we establish a virus structure and molecule model based on the detected gene sequence of Wuhan patient,and calculate irradiated electron interaction with virus atoms via a Monte Carlo simulation that track each elastic and inelastic collision of all *** characteristics of irradiation damage on COVID-19,atoms’ionizations and electron energy losses are calculated and analyzed with *** simulate the different situations of incident electron energy for evaluating the influence of incident energy on virus *** is found that under the major protecting of an envelope protein layer,the inner RNA suffers the minimal *** damage for a^100-nm-diameter virus molecule is not always enhanced by irradiation energy monotonicity,for COVID-19,the irradiation electron energy of the strongest energy loss damage is 2 keV.

关键词： electron beam irradiation novel coronavirus(COVID-19) numerical simulation

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novel OXIDATION OF HEXABENZYLHEXAAZA-ISOWURTZITANE BY Me_2CHNO_2/CuCl/Py/O_2

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Chinese Chemical Letters 1996年第6期7卷 511-512页

作者： Guan, XP Yan, H Sun, JG Yu, YZ BEIJING INST TECHNOL SCH CHEM ENGN & MAT SCIBEIJING 100081PEOPLES R CHINA

Treatheent of2.4. 6. 8, 10.12-hexahany1-2.4. 6, 8,10, 12-hexaazateteracyclo [5.***.0.03.9 03.11]dodecane (1) with ***2/CuCl/Py/O2 results in C(1)-C(7) okidative cleavop to give 1,3.4,5,7,8-hexabenzy-2,6-dioxo-cis-cisid... 详细信息

关键词： CuCl Me2CHNO2 ISOWURTZITANE BY novel OF OXIDATION Py

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novel INTEGRATED DESIGN STRATEGIES FOR NET-ZERO-ENERGY SOLAR BUILDINGS(NZESBS)IN NANJING,CHINA

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Journal of Green Building 2015年第3期10卷 89-115页

作者： Changhai Peng Lu Huang Bangwei Wan School of Architecture Southeast UniversityNanjing 210096PR China Key Laboratory of Urban and Architectural Heritage Conservation(Southeast University) Ministry of EducationPR China College of Engineering and Applied Science University of Colorado DenverDenverCO 80217USA Architects and Engineers CO.LTD.of Southeast University Nanjing 210096PR China

The connotations and denotations of the term net-zero-energy solar buildings(NZESBs)have been in constant flux because of continuous developments in solar heating technology,solar photovoltaic(PV)technology,building energy-storage technology,regional energy-storage technology,and energy-management *** paper focuses on innovative strategies for implementing NZESBs in Nanjing,*** strategies include integrated architectural design,including passive solar design(respecting climatic characteristics and conducting integrated planning based on the environment,building orientation,distance between buildings,build-ing shape,ratio of window area to wall area,and building envelope)and active solar design(integration of the solar-energy-collecting end of the system–collectors and PV panels–with the building surface–roof,wall surfaces,balconies,and sun-shading devices–and the integration of solar-energy transfer and storage equip-ment with the building).Some Nanjing-specific recommendations and findings on NZESBs are *** results illustrate that NZESBs can be realized in Nanjing if solar energy technologies are appropriately integrated with the character-istics of Nanjing’s geography,climate and buildings.

关键词： novel integrated design strategies net-zero-energy solar buildings Nanjing

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novel　Type　CO_2　Methanation　Catalysts　over　Ni／Sepiolite　and　Ru／Sepiolite　System

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Chinese Chemical Letters 1996年第10期7卷 956-959页

作者： Deng, GC Xu, L Mu, RC Chen, RT Lu, W NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA TIANJIN ENVIRONM PROTECT BUR TIANJIN 300191PEOPLES R CHINA

A novel type single-component catalyst in which small amounts of nickel of ruthenium supported on sepiolite nas found to be a very efficient methanation catalyst for carbon dioxide at high space velocity.

关键词： Ru and Type over Methanation novel Sepiolite System CO2 Catalysts 二氧化碳 Ni

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