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Topographic tear film trend and new parameters for noninvasive break up time test

International Journal of Ophthalmology(English edition) 2022年第12期15卷 1932-1939页

作者： Yakup Acet Department of Ophthalmology Mardin Training and Research HospitalMardin 47100Turkey

AIM:To evaluate the quantitative and qualitative results of the noninvasive tear film break-up time(NI-BUT)test and investigate the predictive ability of the new NIBUT parameter in discriminating between normal Ocular Surface Disease Index(OSDI;scores≤12)and abnormal OSDI(scores≥13).METHODS:A total of 341 eyes of 341 volunteers who applied for routine eye outpatient control were included in the prospective *** participants'noninvasive first tear film break-up time(NIF-BUT),noninvasive average tear film break-up time(NIAvg-BUT)and average value of the first three break-up time(A3F-BUT)were analyzed.A3F-BUT,the new NI-BUT parameter,is calculated by adding the NIF-BUT value to the 2^(nd )break-up time value that has a difference of at most 1 second from the NIF-BUT value and to the 3^(rd) break-up time and then dividing the respective sum by *** operating characteristic(ROC)curve and forward logistic regression analyses were performed to determine the parameter that had the best predictive ability between the OSDI ***:The NI-BUT values of 255 eyes of 255 volunteers included in the study were analyzed *** mean NIF-BUT,NIAvg-BUT,and A3F-BUT values were calculated as 5.3±3.0,8±3.1,and 5.8±3.0 seconds,*** three parameters were found to be significantly lower in the abnormal OSDI group(P=0.014,0.034,and 0.011,respectively).The area under the curve(AUC)of the A3F-BUT to predict abnormal OSDI was AUC=0.625(0.529-0.720),P=0.011 and NIF-BUT was AUC=0.599(0.502-0.696),P=*** A3F-BUT parameter and NIF-BUT parameters were found to be significantly efficient in discriminating abnormal ***:The new parameter for the NI-BUT test has more predictive ability in the discrimination of OSDI groups.

关键词： noninvasive break-up time Ocular Surface Disease Index tear film topographic break-up time test

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