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Medicinal uses,phytochemistry and pharmacology of Picralima nitida(Apocynaceae) in tropical diseases:A review

Asian Pacific Journal of Tropical Medicine 2014年第1期7卷 1-8页

作者： Osayemwenre Erharuyi Abiodun Falodun Peter Langer Institute of Chemistry University of RostockAlbert-Einstein-Str.3A18059 RostockGermany Department of Pharmacognosy School of PharmacyUniversity of Mississippi38655 OxfordMississippiUSA

Picralima nitida Durand and Hook,(***)is a West African plant with varied applications in African folk *** parts of the plant have been employed ethnomedicinally as remedy for fever,hypertension,jaundice,dysmenorrheal,gastrointestinal disorders and *** order to reveal its full pharmacological and therapeutic potentials,die present review focuses on the current medicinal uses,phytochemistry,pharmacological and toxicological activities of this *** survey on scientific journals,books as well as electronic sources have shown the isolation of alkaloids,tannins,polyphenols and steroids from different parts of the plant,pharmacological studies revealed that the extract or isolated compounds from this species posses analgesic,anti-inflammatory,hypoglyceamic,hypotensive,antiplasmodial,antimicrobial,antiulcer and antitumorigenic *** from various scientific investigations to date have revealed the potential of the extract from the plant or isolated compounds for use in the treatment and prevention of various kinds of human ***,further studies on the extracts and pure compounds from this species is required to completely assess its phytoc-hemical,pharmacological and toxicological profile as well as the mechanism of action behind these pharmacological activities exhibited by the compounds isolated from this species.

关键词： Picralima nitida Apocynaceae Phytochemistry Pharmacology

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Antiulcer activity of methanolic extract and fractions of Picralima nitida seeds(Apocynacaea) in rats

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Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 13-15页

作者： Okonta Jegbefume Mathew Adibe Maxwell Ogochukwu Ubaka Chukwuemeka Michael Department of Clinical Pharmacy and Pharmacy Management Faculty of Pharmaceutical SciencesUniversity of NigeriaNsukka

Objective:To investigated the antisecrectory activities of the methanol extract,chloroform fraction and methanol fraction of Picralima nitida ***:The methanol extract of Picralima nitida seeds was fractionated into chloroform fraction and methanol *** were evaluated for antiulcer activity and gastric emptying time in rats using aspirin-pylorus-ligation ***:Oral administration of the methanol extract,chloroform fraction and methanol fraction at 1 000 mg/kg reduced gastric ulcer by 56.4%,40.0%and 56.3%,respectively;and the fractions of the extract significantly(P<0.05) reduced gastric emptying time when compared to the *** acidity was significandy decreased when compared with saline group,40.25 mEq/ L in methanol extract,50.0 mEq/L in chloroform fraction 51.25 mEq/L in methanol fration but had no significant effect on the gastric secretion ***:These findings showed that methanol extract,chloroform fraction and methanol fraction of the seeds of Picralima possessed potent antiulcer properties and some antisecretory properties.

关键词： Picralima nitida Aspirin-pylorus-ligation Antiulcer Rats

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Influence of Post-Harvest Storage Technologies on Weight and Rate Losses and Sensory Profile of Cola Nuts (<i>Cola nitida</i>) Produced in Côte d’Ivoire

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Open Journal of Applied Sciences 2018年第9期8卷 371-380页

作者： Jean-Marc N’Guessan Elisée Yapi Kouakoua Nestor Kouakou Kouassi Georges N’Guessan Amani Department of Food Sciences and Technologies Nangui Abrogoua University Abidjan C&ocirc te d’Ivoire

The conservation of cola nuts (Cola nitida) poses a real problem in Côte d’Ivoire because of the post-harvest losses. The objective of this study was to evaluate the impact of post-harvest technologies on organoleptic and physical properties of cola nut during storage. A biopesticide, glucose syrup and biopesticide + glucose syrup were applied to fresh cola nuts before conditioning and kept at 28°C for 6 weeks. Physicochemical and sensory analyses were performed to check the quality of the nuts during storage. The results showed that the biopesticide keep cola nuts better than the others methods with only 11.66% ± 3.04% and 13.66% ± 3.95% of loss rates for white and red cola nuts respectively. Cola nuts treated with bio-pesticide retain significantly their freshness with 62.00% ± 1.15% of moisture for white nuts and 64.00% ± 2.00% of moisture for red nuts compared to those treated with glucose syrup and bio-pesticide + glucose syrup (56.66% ± 1.15%). Cola nuts treated with biopesticide have a better acceptability compared to those subjected to others treatments. The use of biopesticide for the storage of cola nuts minimizes the losses and maintains the quality whatever the type of cola.

关键词： Cola nitida Storage Post-Harvest Losses Biopesticide Glucose Syrup Quality

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