检索结果-南通市图书馆

Silicon-based microelectrode arrays for stimulation and signal recording of in vitro cultured neurons

Science China(Information Sciences) 2011年第10期54卷 2199-2208页

作者： PAN HaiXian 1,L XiaoYing 1 ,WANG ZhiGong 2,REN TianLing 3,FANG Tao 1,ZHANG Jie 1,ZHOU ChangJian 3 & WANG LiGang 3 1 State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China 2 Institute of RF-& OE-ICs,Southeast University,Nanjing 210096,China 3 Institute of Microelectronics,Tsinghua University,Beijing 100084,China 1. State Key Laboratory of Bioelectronics Southeast University Nanjing 210096 China2. Institute of RF-& OE-ICs Southeast University Nanjing 210096 China3. Institute of Microelectronics Tsinghua University Beijing 100084 China

Microelectrode arrays (MEAs) for stimulation and signal recording of in vitro cultured neurons are *** MEA is composed of 60 independent electrodes with 59 working ones and one reference *** electrodes are divided into 30 *** each pair of electrodes,four independent states can be realized to define the accessing modes of neurons cultured on the surface of the electrodes.A total MEA covers an area of 10 mm×10 *** are fabricated in a silicon-based semiconductor *** implemented MEA is bonded on a specially designed printed-circuit-board (PCB) and surrounded by a culture *** impedance measurement has been made to verify the electrical characteristics of *** surface was modified to enhance the biocompatibility.A series of PC12 cells culture experiments validates the effectiveness of the *** extracellular signal recording experiment with acetylcholine (Ach) as a stimulant has been carried out,and the results show the feasibility of MEAs for extracellular action potential *** electrical stimulation and recording experiments have been carried out *** indicate that MEAs can be used for extracellular stimulation,recording,simultaneous stimulation and recording,and isolation of PC12 cells network cultured in vitro.

关键词： microelectrode arrays (MEAs) extracellular recording stimulation and recording neurons net-work in vitro

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：