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Diabetic kidney disease treated with a modified Shenzhuo formula derived from Traditional Chinese Medicine:a case report

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Journal of Traditional Chinese Medicine 2017年第6期37卷 854-861页

作者： Guo Jing Zhen Hongdong Zhao Xiyan Zhao Linhua Tong Xiaolin [1Department of Endocrinology Guang'anmenHospital of ChinaAcademy of Chinese Medical SciencesBeijing 00054China Department of Endocrinology Guang'anmen Hospitat of ChinaAcademy of Chinese Medical SciencesBeijing 100054ChinaDepartment of EndocrinologyBeijing Hepingli HospitalBeiiina 100013.China Department of Endocrinology Guang'anmen Hospital of ChinaAcademy of Chinese Medical SciencesBeijing 100054China Department ot Molecular and Biology Guang'anmen Hospital of ChinaAcademy of Chinese Medical SciencesBeijing 100054ChinaDepartmentof EndocrinologyGuang'anmen Hospital of ChinaAcademy of Chinese Medical SciencesBeijing 100054China

INTRODUCTION: Diabetic kidney disease(DKD) is one of the most common microvascular complications of diabetes mellitus and is the leading cause of end-stage renal disease. DKD seriously affects the quality of life of patients and brings heavy economic burden to the country. At present, the pathogenesis of DKD is not entirely clear, and clinical treatment is mainly to control blood glucose and lower blood pressure and urine protein. However,the clinical effect is not *** PRESENTATION: A female patient, aged 72 years, first visited our hospital endocrinology clinic,and was diagnosed with DKD. She suffered from fatigue, cold sensation in the lower extremities, convulsion of the lower limbs and frequent urination at night. She had a dark purple tongue with white and yellow fur and sublingual varices. Accessory examinations showed that her fasting blood glucose was 5.7 mmol/L, serum creatinine 159 μmol/L,blood urea nitrogen 13.6 μmol/L, blood uric acid493 μmol/L, and blood pressure 138/65 mm *** patient received Traditional Chinese Medicine treatment of the modified Shenzhuo formula[Huangqi(Radix Astragali Mongolici), Dahuang(Radix Et Rhizoma Rhei Palmati), Shuizhi(Hirudo) and Danshen(Radix Salviae Miltiorrhizae)] for 7 years and achieved good ***: This case provides a specific treatment plan and an effective reference for clinical application of Traditional Chinese Medicine for treating DKD. This may be an alternative treatment for DKD.

关键词： Diabetic nephropathies Medicine, Chi-nese traditional Shenzhuo formula Case reports

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Patient selection and preparation strategies for the use of contrast material in patients with chronic kidney disease

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World Journal of Radiology 2012年第6期4卷 253-257页

作者： Poul Erik Andersen Department of Radiology Odense University HospitalSdr.BoulevardDK-5000 Odense CDenmark

The prevalence of chronic kidney disease and peripheral arterial disease is ***,it is increasingly problematic to image these patients as the number of patients needing a vascular examination is increasing *** high-risk patients with impaired kidney function,intravascular administration of iodinated contrast media can result in contrast-induced acute kidney injury and Gadolinium can induce nephrogenic systemic fibrosis(NSF).It is important to identify these highrisk patients by means of se-creatinine/e glomerular filtration *** indication for contrast examination should counterbalance the increased *** or more alternative examination methods without contrast media,such as CO 2 angiography,Ultrasound/Doppler examination or magnetic resonance angiography without contrast should be considered,but at the same time,allow for a meaningful outcome of the *** contrast is deemed essential,the patient should be well hydrated,the amount of contrast should be restricted,the examination should be focused,metformin and diuretics stopped,and renal function *** bicarbonate and N-acetylcysteine are popular but their efficiency is not *** is no evidence that dialysis protects patients with impaired renal function from contrast-induced nephropathy or NSF.

关键词： Arterial disease Peripheral Radiology Interventional Diabetes complications nephropathies Diabetic Renal insufficiency Chronic Kidney failure

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