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neck observation versus elective neck dissection in management of clinical T1/2N0 oral squamous cell carcinoma: a retrospective study of 232 patients

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Chinese Journal of Cancer Research 2017年第3期29卷 179-188页

作者： Xiangqi Liu Xiaomei Lao Lizhong Liang Sien Zhang Kan Li Guiqing Liao Yujie Liang Department of Oral and Maxillofacial Surgery Guanghua School of Stomatology Guangdong Provincial Key Laboratory of Stomatology Sun Yat-sen University Department of Oral and Maxillofacial Surgery the Fifth Affiliated Hospital Sun Yat-sen University

Objective: The management of early-stage (cT1/2N0) oral squamous cell carcinoma (OSCC) remains a controversial issue. The aim of this study was to compare the clinical outcomes of neck observation (OBS) and elective neck dissection (END) in treating patients with cT1/2N0 OSCC. Methods: A total of 232 patients with cT1/2N0 OSCC were included in this retrospective study. Of these patients, 181 were treated with END and 51 with OBS. The survival curves of 5-year overall survival (OS), disease-specific survival (DSS), and recurrence-free survival (RFS) rates were plotted using the Kaplan-Meier method for each group, and compared using the Log-rank test. Results: There was no significant difference in 5-year OS and DSS rates between END and OBS groups (OS: 89.0% vs. 88.2%, P=0.906; DSS: 92.3% vs. 92.2%, P=0.998). However, the END group had a higher 5-year RFS rate than the OBS group (90.1% vs. 76.5%, P=0.009). Patients with occult metastases in OBS group (7/51) had similar 5-year OS rate (57.1% vs. 64.1%, P=0.839) and DSS rate (71.4% vs. 74.4%, P=0.982) to those in END group (39/181). In the regional recurrence patients, the 5-year OS rate (57.1% vs. 11.1%, P=0.011) and DSS rate (71.4% vs. 22.2%, P=0.022) in OBS group (7/51) were higher than those in END group (9/181). Conclusions: The results indicated that OBS policy could obtain the same 5-year OS and DSS as END. Under close follow-up, OBS policy may be an available treatment option for patients with clinical T1/2N0 OSCC.

关键词： Lymphatic metastasis neck dissection neck observation oral squamous cell carcinoma survival

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THE UNILATERAL BIG HOCKEY STICK INCISION FOR neck dissection IN THYROID CARCINOMA

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Chinese Journal of Cancer Research 2001年第4期13卷 291-293页

作者：刘宝国刘伟顾晋 Department of Surgical Oncology School of Oncology Peking University Beijing Institute for Cancer Research Beijing Cancer Hospital Beijing 100036 Department of Surgical OncologyDepartment of Surgical Oncology Zhengzhou Third Hospital Zhengzhou 450001

Objective: To investigate the feasibility and advantages of the unilateral big hockey stick incision in thyroid carcinoma. Method: neck dissection using the unilateral big hockey stick incision was performed on 23 patients with thyroid carcinoma. Results: The big hockey stick incision results in a cosmetic scar which is barely visible and easily covered by hair or clothing, while it provides sufficient exposure of the operation field. A small area of marginal necrosis is occasionally seen at the apex of the skin flap due to preoperative radiotherapy. Conclusion: The unilateral big hockey stick incision has adequate surgical access, good healing of skin flaps, and a good cosmetic result.

关键词： Incision neck dissection Thyroid carcinoma

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UNILATERAL BIG HOCKEY STICK INCISION FOR neck dissection IN HEAD AND neck CARCINOMA

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Chinese Journal of Cancer Research 2004年第3期16卷 193-196页

作者：刘宝国赵振生李明强陈荣鋭王建军张乃嵩 Department of Head and neck Surgery and Surgical Oncology Peking University School of Oncology Beijing Institute for Cancer Research Beijing Cancer Hospital Department of Surgery Liangxiang Hospital Department of Head and neck Surgery and Surgical Oncology Peking University Shougang Hospital

Objective: To investigate for the feasibility and advantages performed by the unilateral big hockey stick incision (BHSI) in head and neck carcinoma. Methods: neck dissection by using the unilateral big hockey stick incision (BHSI) was performed on 93 patients with head and neck carcinoma. Results: The big hockey stick incision has a cosmetic scar and not scar contraction and is barely visible and easily covered in hair and clothing; sufficient exposure of the operation field; a small area of marginal necrosis was occasionally seen at the apex of the skin flap due to having preoperative radiotherapy. Conclusion: The unilateral big hockey stick incision has adequate surgical access, good healing of skin flaps, and a good cosmetic result.

关键词： Incision neck dissection Head and neck carcinoma

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neck dissection does not add to morbidity or mortality of laryngectomy

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World Journal of Otorhinolaryngology-Head and neck Surgery 2019年第4期5卷 215-221页

作者： Christopher C.Xiao Sarah A.Imam Shaun A.Nguyen Marc P.Camilon Andrew B.Baker Terry A.Day Eric J.Lentsch Department of Otolaryngology-Head and neck Surgery Kaiser PermanenteNorthern CaliforniaOaklandCA94612USA Department of Health and Human Performance The CitadelCharlestonSC29409USA Department of Otolaryngology-Head and neck Surgery Medical University of South CarolinaCharlestonSC29425USA Oregon Health&Science University Ear Nose&ThroatPortlandOR97239USA

Objectives:To examine the national rates of complications,readmission,reoperation,death and length of hospital stay after *** explore the risks of neck dissection with laryngectomy using ***:The American College of Surgeons National Quality Improvement Program(ACS-NSQIP)database was reviewed *** database was analyzed for patients undergoing laryngectomy with and without neck ***,perioperative complication,reoperation,readmission,and death variables were ***:754 patients who underwent total laryngectomy during this time were *** analysis showed average age was 63 years old,566(75.1%)were white,and 598(79.3%)were *** these patients,520(69.0%)included a neck dissection while 234(31.0%)did *** comparing patients who received a neck dissection to those who did not,there were no significant differences in median length of hospital stay(12.5 days w/vs.13.3 days w/o,P=0.99),rates of complication(40%w/vs.35%w/o,P=0.23),reoperation(13.5%w/vs.14%w/o,P=0.81),readmission(14%w/vs.18%w/o,P=0.27),and death(1.3%w/vs.1.3%w/o,P>0.99).Furthermore,neck dissection did not increase the risk of complication(P=0.23),readmission(P=0.27),reoperation(P=0.81),death(P=0.94),or lengthened hospital stay(P=0.38).Conclusions:Concurrent neck dissection does not increase postoperative morbidity or mortality in patients undergoing total *** results may help physicians make decisions regarding concurrent neck dissection with total laryngectomy.

关键词： Laryngectomy neck dissection Total laryngectomy Complication rates Outcomes

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Rational radical neck dissection for oral cancer

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Chinese Medical Journal 2003年第8期116卷 1123-1126页

作者：李龙江温玉明王昌美王莉娟 Department of Oral Maxillofacial Surgery West China College of StomatologySichuan University

The main target of a radical tumor operation is to save patients' lives. So the radical effects must be assured. At the same time, quality of life and organ function should be considered and kept as much as possible. The above-discussed RND, which maintains the EJV and deep branches of the cervical plexus, can reduce intracranial complications and improve postoperative shoulder without influencing radical effects. This technique could be used to treat cervical metastases of oral cancer as a regular operation.

关键词： Humans Mouth Neoplasms neck dissection

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neck dissection Research for Oral Squamous Cell Carcinoma: A Bibliometric Analysis

Neck Dissection Research for Oral Squamous Cell Carcinoma: A...

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2020年全国口腔颌面-头颈肿瘤学术大会暨中华口腔医学会口腔颌面-头颈肿瘤专业委员会学术年会——创新超越、共赢未来

作者：姜洲吴沉洲李若焓李一四川大学华西口腔医(学)院四川大学华西口腔医院

Purpose/Background:neck dissection for oral squamous cell carcinoma(OSCC) has been a clinically controversial issue all the time and has therefore been the subject of a great deal of research. However, none has employed a bibliometric analysis of this topic up to date. The aim of this study was to assess the development of neck dissection research for OSCC: historical evolution, current hotspots and future directions,

关键词： neck dissection oral squamous cell carcinoma bibliometric analysis invasion depth of invasion N0 negatve neck

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A new device for the identification of lymph nodes removed during different types of neck dissection

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Health 2010年第9期2卷 1093-1096页

作者： Imre Gerlinger Tamas Ferenc Molnar Tamas Jarai Peter Moricz Gabor Rath Gyula Gobel Department of Otorhinolaryngology&Head and neck Surgery Medical SchoolUniversity of PecsPecsHungary Department of Otorhinolaryngology&Surgery Medical SchoolUniversity of PecsPecsHungary

Meticulous mapping of the lymph node status is a general principle in present-day head and neck surgery. The removal of a certain number of lymphatic levels during neck dissection may well be therapeutic in intent, but it is also mandatory for correct tumour staging. We pre- sent a precise lymph node mapping during dif- ferent types of neck dissection in the course of major head and neck surgery by a sterile plastic tray moulded in the shape of the neck. This de- vice makes lymph node mapping simpler, safer, quicker and methodically more structured than any of the present methods. It facilitates the work of the pathologist and the flow of reliable information along the surgeon-pathologist- oncologist chain. With this device, a more stru- ctured, methodical means of lymph node removal has become possible.

关键词： Head and neck Surgery Lymph Node Mapping neck dissection

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Evaluation of pre- and post- neck dissection cognitive function of patients with oral cancer

Evaluation of pre- and post- neck dissection cognitive funct...

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中华口腔医学会第14次全国口腔医学学术会议（2012年会）

作者： Department of Oral and Maxillofacial Surgery,Guanghua School of Stomatology, Sun Yat-Sen University.56 Lingyuanxi Road,Guangzhou,510055,P.R.China Lao Xiaomei

Cancer and Alzheimer’s disease are two of the four major killers in the elderly. Malignant tumor of the oral cavity is very commonly seen,and shares lots of risk factors with *** the high incidence of lymphatic metastasis,neck dissection counts a lot in treatment of oral ***,after neck dissection,people often appear as dysphoria,change of personality,and damage of memory,these prolonged the recovery of surgery,and lowered patients’ quality of ***,there is little study about the cognitive level of oral cancer,and whether or not oncologic neck dissection will cause postoperative cognitive decline(POCD)is unknown. With the progress of medical science,treatment of cancer is no longer as simple as prolonging patient’s life,but also raising their quality of *** this study,we focus on the cognitive function of patients with oral cancer,evaluating the cognitive function both before and after oncologic neck dissection,to find out whether oral cancer or oncologic neck dissection have something to do with cognitive impairment(CI),so that we can give an evidence to clinical workers to prevent CI of oral cancer from happening or progressing,and eventually,increase patients’ quality of life. Objective Investigate the change of cognition level of patients with oral cancer before and after oncologic neck dissection,so as to provide evidence to clinical workers to prevent CI from happening or progressing. Method A total of 27 cases were collected with patients accepted oncologic neck dissection during March 2011 to March 2012 in Guanghua Hospital of Stomatology,Sun Yat-sen ***- and post-operative cognitive function was assessed by MoCA Chinese version as well as observation of clinical symptom,and statistical analysis was conducted using group t-test,x test and regression in SPSS 19.0 software,to monitor the different cognition level of oral and maxillofacial malignancy both before and after oncologic neck dissection. Result *** incidence of

关键词： oral cancer neck dissection cognitive function cognitive impairment

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neck dissection for recurrent and persistent lymph nodes of nasopharyngeal carcinoma after radiotherapy： effect and choice

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The Chinese-German Journal of Clinical Oncology 2009年第2期8卷 81-85页

作者： Liangping Xia Zongyuan Zeng Zhuming Guo Guifang Guo Bei Zhang Huijuan Qiu Feifei Zhou VIP region Cancer Center Sun Yat-sen University National Laboratory of Oncology in Southern China Guangzhou 510060 China

Objective： To investigate the best surgical mode for the patients of nasopharyngeal carcinoma with recurrent and persistent lymph nodes after radiotherapy. Methods： The clinical data of 88 patients of nasopharyngeal carcinoma with recurrent and persistent lymph nodes after radiotherapy were analyzed retrospectively. The levels of involved lymph nodes and the relationship among the levels were analyzed; the survival rate and recurrent rate of the surgical modes including radical neck dissection （RND）, modified radical neck dissection （MRND）, selective neck dissection （SND）, and lymph node resection （LNR） were analyzed; the role of postoperative radiotherapy was evaluated. Results：（1） The recurrent and persistent lymph nodes mainly located in level Ⅱ（55.6% and 58.6%, respectively）, next was level Ⅲ and rarely in level Ⅳ, Ⅴ, and Ⅰ, but the number of levels Ⅳ Ⅴ, and Ⅰ with cancer-bearing lymph nodes was relatively more than that of clinical measurement. （2） Patients with lymph nodes involved in level Ⅲ and Ⅳ, usually, have other levels involved simultaneously; the percentages were 63.6% and 88.9%, respectively. However, the lymph nodes in level Ⅱ and Ⅴ were mainly isolated. （3） The 5-year survival rate and recurrent rate of the whole group were 42.77% and 22.7%, respectively. （4） The 5-year survival rates of RND, MRND, SND, and LMR groups were 39.75%, 60.00%, 37.87%, and 44.10%, respectively; the differences were insignificant （Log-rank = 1.0, P = 0.8011）; the recurrent rate between the extensive and local surgery groups were insignificant （X^2 = 0.470, P = 0.493）. （5） The 5-year survival rates of the patients with and without postoperative radiotherapy were 39.06% and 45.26%, respectively; the difference was insignificant （Log-rank = 0.06, P = 0.8138）. Conclusion： The extensive surgery was recommended when the recurrent and persistent lymph nodes were more than one level involved or very large or immovable, otherwise, the SND should be performed and postoperative radi

关键词： nasopharyngeal carcinoma cervical lymph node neck dissection surgical modes prognosis

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A critical readability and quality analysis of internet-based patient information on neck dissections

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World Journal of Otorhinolaryngology-Head and neck Surgery 2023年第1期9卷 59-65页

作者： Elysia M.Grose Hyun Joo Kim Justine Philteos Marc Levin Jong Wook Lee Eric A.Monteiro Department of Otolaryngology-Head and neck Surgery University of Toronto6 Queen's Park Crescent WestTorontoM5S 3H2ONCanada Temerty Faculty of Medicine University of Toronto1 King's College CircleTorontoM5S 1A8ONCanada Department of Otolaryngology-Head and neck Surgery Sinai Health System600 University AvenueTorontoM5G 1×5ONCanada

Objective:Patients are increasingly turning to the Internet as a source of healthcare *** that neck dissection is a common procedure within the field of Otolaryngology-Head and neck Surgery,the aim of this study was to evaluate the quality and readability of online patient education materials on neck ***:A Google search was performed using the term"neck dissection."The first 10 pages of a Google search using the term"neck dissection"were *** DISCERN instrument was used to assess quality of *** was calculated using the Flesch-Reading Ease,Flesch-Kincaid Grade Level,Gunning-Fog Index,Coleman-Liau Index,and Simple Measure of Gobbledygook ***:Thirty-one online patient education materials were ***-five percent(n=17)of results originated from academic institutions or *** mean Flesch-Reading Ease score was 61.2±***-two percent(n=16)of patient education materials had Flesch-Reading Ease scores above the recommended score of *** average reading grade level was 10.5±*** average total DISCERN score was 43.6±*** 26%of patient education materials(PEMs)had DISCERN scores corresponding to a"good quality"*** was a significant positive correlation between DISCERN scores and both Flesch-Reading Ease scores and average reading grade ***:The majority of patient education materials were written above the recommended sixth-grade reading level and the quality of online information pertaining to neck dissections was found to be *** research highlights the need for patient education materials regarding neck dissection that are high quality and easily understandable by patients.

关键词： Health literacy neck dissection Online patient education materials Quality Readability

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