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Recent advances in multi-metallic-based nanozymes for enhanced catalytic cancer therapy

BMEMat(BioMedical Engineering Materials) 2024年第1期2卷 30-48页

作者： Mingjin Cui Bo Xu Lianhui Wang Key Laboratory for Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)School of Chemistry and Life SciencesNanjing University of Posts and TelecommunicationsNanjingChina

nanozymes have emerged as a promising alternative to natural enzymes,effectively addressing natural enzymes'inherent *** and potential applications of nanozyme span across various fields,with catalytic tumor therapy being one prominent *** has sparked significant interest and exploration in the utilization of nanozymes for targeted cancer *** advancements in interdisciplinary research,nanotechnology,biotechnology,and catalytic technology have led to the emergence of multi-metallicbased nanozymes,which exhibit tremendous potential for further *** review focuses on investigating the synergistic effects of multimetallicbased nanozymes,aiming to enhance our understanding of their catalytic activities and facilitate their broader *** comprehensively survey the remarkable achievements in the synthesis,catalytic mechanisms,and the latest applications of multi-metallic-based nanozymes in cancer catalytic ***,we identify the current limitations and prospects of multi-metallic-based nanozymes in the development of new materials and the application of novel technologies,along with the potential challenges associated with catalytic cancer *** review underscores the significance of multi-metallic-based nanozymes and emphasizes the need for continued exploration as well as their potential impact on the development of novel materials and the realization of breakthroughs in catalytic tumor therapy.

关键词： cancer therapy multi-metallic nanomaterials nanozyme activities synergistic effects

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