检索结果-南通市图书馆

Force-induced Caspase-1-dependent pyroptosis regulates orthodontic tooth movement

International Journal of Oral Science 2024年第2期16卷 238-250页

作者： Liyuan Chen Huajie Yu Zixin Li Yu Wang Shanshan Jin Min Yu Lisha Zhu Chengye Ding Xiaolan Wu Tianhao Wu Chunlei Xun Yanheng Zhou Danqing He Yan Liu Department of Orthodontics Central LaboratoryPeking University School and Hospital for Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental Materials&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijingChina Peking University Hospital of Stomatology Fourth Division BeijingChina

Pyroptosis,an inflammatory caspase-dependent programmed cell death,plays a vital role in maintaining tissue homeostasis and activating inflammatory *** tooth movement(OTM)is an aseptic force-induced inflammatory bone remodeling process mediated by the activation of periodontal ligament(PDL)progenitor ***,whether and how force induces PDL progenitor cell pyroptosis,thereby influencing OTM and alveolar bone remodeling remains *** this study,we found that mechanical force induced the expression of pyroptosis-related markers in rat OTM and alveolar bone remodeling *** or enhancing pyroptosis level could suppress or promote OTM and alveolar bone remodeling *** Caspase-1^(−/−)mice,we further demonstrated that the functional role of the force-induced pyroptosis in PDL progenitor cells depended on ***,mechanical force could also induce pyroptosis in human ex-vivo force-treated PDL progenitor cells and in compressive force-loaded PDL progenitor cells in vitro,which influenced ***,transient receptor potential subfamily V member 4 signaling was involved in force-induced Caspase-1-dependent pyroptosis in PDL progenitor ***,this study suggested a novel mechanism contributing to the modulation of osteoclastogenesis and alveolar bone remodeling under mechanical stimuli,indicating a promising approach to accelerate OTM by targeting Caspase-1.

关键词： homeostasis movement thereby

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats

引用

International Journal of Oral Science 2024年第2期16卷 322-332页

作者： Wenhao Zheng Xiaofeng Lu Guangjin Chen Yufeng Shen Xiaofei Huang Jinfeng Peng Jiajia Wang Ying Yin Wencheng Song Mengru Xie Shaoling Yu Lili Chen Department of Stomatology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina School of Stomatology Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration WuhanChina Department of Stomatology The First Affiliated HospitalSchool of MedicineShihezi UniversityShiheziChina

The utilization of optimal orthodontic force is crucial to prevent undesirable side effects and ensure efficient tooth movement during orthodontic ***,the sensitivity of existing detection techniques is not sufficient,and the criteria for evaluating optimal force have not been yet ***,by employing 3D finite element analysis methodology,we found that the apical distal region(A-D region)of mesial roots is particularly sensitive to orthodontic force in ***-resistant acidic phosphatase(TRAP)-positive osteoclasts began accumulating in the A-D region under the force of 40 grams(g),leading to alveolar bone resorption and tooth *** the force reached 80 g,TRAP-positive osteoclasts started appearing on the root surface in the A-D ***,micro-computed tomography revealed a significant root resorption at 80 ***,the A-D region was identified as a major contributor to whole root *** was determined that 40 g is the minimum effective force for tooth movement with minimal side effects according to the analysis of tooth movement,inclination,and *** findings suggest that the A-D region with its changes on the root surface is an important consideration and sensitive indicator when evaluating orthodontic forces for a rat ***,our investigations into this region would aid in offering valuable implications for preventing and minimizing root resorption during patients’orthodontic treatment.

关键词： movement roots offering

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Towards precision 24-hour movement behavior recommendations—The next new paradigm?

引用

Journal of Sport and Health Science 2024年第6期13卷 743-748页

作者： Mark S.Tremblay Markus J.Duncan Nicholas Kuzik Diego Augusto Santos Silva Valerie Carson CHEO Research Institute OttawaON K1H 8L1Canada Department of Pediatrics University of OttawaOttawaON K1H 8L1Canada Federal University of Santa Catarina Santa Catarina 88040900Brazil Faculty of Kinesiology Sportand RecreationUniversity of AlbertaEdmontonAB T6G 2H9Canada

*** The importance of physical activity(PA)for health is unequivocal.^(1)Accordingly,population-based recommendations for exercise,and more recently public health guidelines for PA,have been developed and released by authoritative groups for many decades.^(2)Such guidelines emerged with leadership from the exercise physiology discipline and were rooted in,and loyal to,the importance of moderate-to-vigorous intensity PA(MVPA)or exercise.

关键词： movement behavior exercise

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Modifying the progression of Parkinson's disease through movement interventions:multimodal quantification of underlying mechanisms

引用

Neural Regeneration Research 2024年第8期19卷 1651-1652页

作者： Manuel Bange Damian Marc Herz Dumitru Ciolac Gabriel Gonzalez-Escamilla Sergiu Groppa Section of movement Disorders and Neurostimulation Department of NeurologyFocus Program Translational Neuroscience(FTN)University Medical Center of the Johannes Gutenberg-University MainzMainzGermany

Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement *** pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain *** r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).

关键词： alterations movement

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Olympic Games and 24-hour movement behaviors:A match worth making

引用

Journal of Sport and Health Science 2024年第6期13卷 728-731页

作者： Mark S.Tremblay Nicholas Kuzik Markus J.Duncan Diego Augusto Santos Silva CHEO Research Institute OttawaON K1H 8L1Canada Department of Pediatrics University of OttawaOttawaON K1H 8L1Canada Federal University of Santa Catarina FlorianopolisSanta Catarina 88040-900Brazil

*** The Olympic motto,"Faster,Higher,Stronger-Together",represents the pursuit of athletic excellence,united as a global community."Excellence,respect and friendship"are the Olympic *** the motto and values are multifaceted and holistic in nature,and all-encompassing in their reach while recognizing no single entity rises above the ***,these foundational statements anchor the Olympic movement in its quest to build a better world through sport.

关键词： movement Together pursuit

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dual roles of the amygdala-hippocampus circuit in the regulation of rapid eye movement sleep and depression symptoms by repetitive transcranial magnetic stimulation in patients with insomnia

引用

General Psychiatry 2024年第2期37卷 297-300页

作者： Xiaoyang Liu Xumeng Zhao Ziqiang Shao Yongjian Guo Lirong Yue Jiayi Liu Dahua Yu Xiaona Sheng Yifei Zhu Kai Yuan School of Life Science and Technology Xidian UniversityXi'anShaanxiChina Department of Psychosomatic Medicine The Second Hospital of Hebei Medical UniversityShijiazhuangHebeiChina Inner Mongolia University of Science and Technology BaotouInner MongoliaChina

To the editor:It is commonly reported that people with insomnia often experience comorbid emotional disorders,such as mood and anxiety disorders.12 A study found that fragmented rapid eye movement(REM)sleep in individuals with insomnia is associated with higher Beck Depression Inventory(BDI)scores.3 REM sleep architecture disruption is a typical symptom of insomnia.

关键词： sleep stimulation movement

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of coke charging pattern on burden movement in COREX melter gasifier based on physical simulation

引用

Journal of Iron and Steel Research International 2022年第6期29卷 907-913页

作者： Li-hao Han Yue-hua Li Li-ning Han Yan-xia Liu Wei-qing Huang Lei Cao Su-ci Qi Xin Guan Jian-lu Yuan Department of Material Engineering Hebei College of Industry and TechnologyShijiazhuang 050091HebeiChina Department of Basic Course Teaching Hebei College of Industry and TechnologyShijiazhuang 050091HebeiChina First Rolling Mill Anyang Iron&Steel Co.Ltd.Anyang 455000HenanChina

A three-dimensional semicircle cold model of COREX melter gasifier(MG)was established,and the effects of coke charging pattern on burden movement were investigated by adopting this *** burden flow pattern of packed bed was measured with different coke charging amounts,coke charging positions,and coke *** results show that the solid flow pattern presents a change from straight line type to reverse U type and finally to W type in MG with traditional coke charging,while the burden flow pattern experiences the change from straight line type to W type with platform and finally W type under center coke charging,and the solid flow pattern presents a change from straight line type to W type with platform and finally W type under intermediate coke *** difference demonstrates that coke charging pattern affects the uniform descending in MG to some *** burden in the coke charging zone keeps a straight line *** matter what kind of coke charging pattern is adopted,the burden residence time is shortened with the increase in coke charging amount,and the vertex of deadman decreases obviously,which is conducive to the renewal of the *** appropriate coke charging amount and coke size should be well controlled at 8.7%and 5 mm,*** results are useful not only in developing further understanding of solid flow in MG but also in verifying different mathematical models,particularly the coupled discrete element method with computational fluid dynamics simulation which has been increasingly used in the literature.

关键词： COREX melter gasifier Coke charging pattern Burden movement Flow pattern Physical simulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frequency-amplitude behavior in the incipient movement of grains under vibration

引用

Particuology 2018年第5期16卷 1-9页

作者： Karina A.Valenzuela Aracena Jesica G.Benito Luc Oger Irene Ippolito Rodolfo O.Ufiac Ana M.Vidales INFAP.CONICET Departamento de FfsieaFacultad de Ciencias Fisico Matemdticas y NaturalesUniversidad Nacional de San LuisEjerdto de los Andes 950D5700HHWSan LuisArgentina Institut de Physique de Rennes UMR UR1-CNRS 6251Universite de Rennes 1263Avenue du General LeclercCampus de BeaulieuCS 7420535042 Rennes CedexFrance Universidad de Buenos Aires Facultad de IngenierfaGrupo de Medios PorososPaseo Colon 8501063Buenos AiresArgentina

The onset of the movement of particles placed on a horizontal rough surface subject to a vertical sinusoidal vibration is investigated through tracking experiments,theoretical analysis,and numerical simulations. The frequency of vibration needed to move particles decays exponentially with the amplitude of the oscillatory *** behavior is explained through a simple mechanism in which a forced damped harmonic oscillator with a spring constant represents all the interactions between the particle and the *** numerical results compare well with experimental data,demonstrating that the forces included in the numerical calculations suitably account for the main particle response,even though the complexity of the surface is not fully taken into *** the way in which frequency varies with amplitude could be relevant to technological applications such as cleaning of material surfaces.

关键词： Vibration Incipient movement Forced oscillator 3D DEM simulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atomic simulation for influence of helium atom on movement of edge dislocation in nickel

引用

Transactions of Nonferrous Metals Society of China 2015年第8期25卷 2666-2674页

作者：阳喜元岭南师范学院物理科学与技术学院湛江524048

The molecular dynamics （MD） simulation and the modified analytical embedded-atom method （MAEAM） were used to study the influence of a He atom on the movement of the（a/2）？110？{111} edge dislocation in Ni. First, the calculated Burgers vector distribution shows that the equilibrium dissociation distance （Ded） and the stacking fault energy （Esf） between two partial edge dislocations are about 25.95 ？ and 108 mJ/m2, respectively. Then, the obtained formation energies （Ef） of a He atom at some different sites demonstrate that the He atom is attracted and repelled in the tension and compression regions, respectively. And the He？dislocation interaction reveals that an interstitial He atom plays a more significant role in the dislocation movement than a substitutional He atom. Finally, it is found that the movement of an interstitial He atom is apparent as the first partial dislocation bypasses and the edge dislocation offers fast-diffusion path for the migration of a He atom.

关键词： movement edge dislocation He atomic simulation Ni

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Strata movement and stress evolution when mining two overlapping panels affected by hard stratum

引用

International Journal of Mining Science and Technology 2019年第5期29卷 691-699页

作者： Jianguo Zhang Wei Yang Baiquan Lin Jinjing Zhang Man Wang State Key Laboratory of Coking Coal Exploitation and Comprehensive Utilization China Pingmei Shenma GroupPingdingshan 467000China Key Laboratory of Gas and Fire Control for Coal Mines(China University of Mining and Technology) Ministry of EducationXuzhou 221116China China Pingmei Shenma Group Pingdingshan 467000China School of Safety Engineering China University of Mining and TechnologyXuzhou 221116China

Mining causes stress redistribution and stratum *** this paper,a numerical model was built according to the geological conditions in the 12th coal mine in Pingdingshan city to study the strata movement and the evolution of stress when mining two overlapping longwall panels,named panels#14 and#*** strata close to the mined panel move directly towards the gob,while the strata that are farther away swing back and forth during the mining *** directed movement and swinging can break the transverse boreholes for gas extraction;a surface borehole should not be within the range of directional *** stress evolution suggested that the mining of the lower panel#15 after the upper panel#14 would further increase the de-stressed range,while the stress concentration around the mined panel would be *** strata usually carry a greater stress than adjacent rocks and soft coal *** stress in a hard stratum increases greatly,and the stress decreases greatly in the coal seams below the hard *** study supplies a reference for similar coal mines and is useful for determining the de-stressed range and transverse borehole arrangement for gas extraction.

关键词： Stratum movement Mining Longwall panel Hard stratum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：