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Effects of cortical intermittent theta burst stimulation combined with precise root stimulation on motor function after spinal cord injury: a case series study

引用

Neural Regeneration Research 2022年第8期17卷 1821-1826页

作者： Ye-Ran Mao Zhong-Xia Jin Ya Zheng Jian Fan Li-Juan Zhao Wei Xu Xiao Hu Chun-Ya Gu Wei-Wei Lu Guang-Yue Zhu Yu-Hui Chen Li-Ming Cheng Dong-Sheng Xu Department of Rehabilitation Baoshan BranchShuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina Institute of Rehabilitation Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Spinal Cord Injury Rehabilitation Shanghai Yangzhi Rehabilitation HospitalShanghai Sunshine Rehabilitation CenterTongji University School of MedicineShanghaiChina Spine Surgery Division of Department of Orthopedics Tongji Hospital Affiliated to Tongji University School of MedicineShanghaiChina Surgery Division of Department of Orthopedics Tongji Hospital Affiliated to Tongji University School of MedicineShanghaiChina Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of EducationShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina

Activation and reconstruction of the spinal cord circuitry is important for improving motor function following spinal cord *** conducted a case series study to investigate motor function improvement in 14 patients with chronic spinal cord injury treated with 4 weeks of unilateral(right only)cortical intermittent theta burst stimulation combined with bilateral magnetic stimulation of L3-L4 nerve roots,five times a *** resting motor evoked potential amplitude was increased,central motor conduction time on the side receiving cortical stimulation was significantly decreased,and lower extremity motor score,Berg balance score,spinal cord independence measure-III score,and 10 m-walking speed were all increased after *** resting motor evoked potential amplitude was positively correlated with lower extremity motor score after 4 weeks of *** findings suggest that cortical intermittent theta burst stimulation combined with precise root stimulation can improve nerve conduction of the corticospinal tract and lower limb motor function recovery in patients with chronic spinal cord injury.

关键词： central motor conduction time intermittent theta burst lower extremity motor score motor evoked potential stimulation neuromodulation neuronal plasticity spinal cord injury transcranial magnetic stimulation

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