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3D printing of tissue engineering scaffolds:a focus on vascular regeneration

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Bio-Design and Manufacturing 2021年第2期4卷 344-378页

作者： Pengju Wang Yazhou Sun Xiaoquan Shi Huixing Shen Haohao Ning Haitao Liu Department of Mechanical Manufacturing and Automation School of Mechatronics EngineeringHarbin Institute of TechnologyHarbin 150001China

Tissue engineering is an emerging means for resolving the problems of tissue repair and organ replacement in regenerative *** supply of nutrients and oxygen to cells in large-scale tissues has led to the demand to prepare blood ***-based tissue engineering approaches are effective methods to form new blood vessel *** demand for blood vessels prompts systematic research on fabrication strategies of vascular scaffolds for tissue *** advances in 3D printing have facilitated fabrication of vascular scaffolds,contributing to broad prospects for tissue *** review presents state of the art on modeling methods,print materials and preparation processes for fabrication of vascular scaffolds,and discusses the advantages and application fields of each ***,significance and importance of scaffold-based tissue engineering for vascular regeneration are *** materials and preparation processes are discussed in *** a focus is placed on preparation processes based on 3D printing technologies and traditional manufacturing technologies including casting,electrospinning,and Lego-like *** related studies are *** of vascular scaffolds to clinical application is ***,four trends of 3D printing of tissue engineering vascular scaffolds are presented,including machine learning,near-infrared photopolymerization,4D printing,and combination of self-assembly and 3D printing-based methods.

关键词： Tissue engineering 3D printing Vascular scaffolds Print materials modeling methods

Disassembly Sequence Planning:A Survey

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IEEE/CAA Journal of Automatica Sinica 2021年第7期8卷 1308-1324页

作者： Xiwang Guo MengChu Zhou Abdullah Abusorrah Fahad Alsokhiry Khaled Sedraoui the College of Computer and Communication Engineering Liaoning Shihua UniversityFushun 113001China the Department of Electrical and Computer Engineering New Jersey Institute of TechnologyNewark NJ 07102 USA the Center of Research Excellence in Renewable Energy and Power Systems King Abdulaziz UniversityJeddah 21481Saudi Arabia the Department of Electrical and Computer Engineering Faculty of Engineeringand the Center of Research Excellence in Renewable Energy and Power SystemsKing Abdulaziz UniversityJeddah 21481Saudi Arabia

It is well-recognized that obsolete or discarded products can cause serious environmental pollution if they are poorly be *** contain reusable resource that can be recycled and used to generate desired economic ***,performing their efficient disassembly is highly important in green manufacturing and sustainable economic *** typical examples are electronic appliances and electromechanical/mechanical *** paper presents a survey on the state of the art of disassembly sequence *** can help new researchers or decision makers to search for the right solution for optimal disassembly *** reviews the disassembly theory and methods that are applied for the processing,repair,and maintenance of obsolete/discarded *** paper discusses the recent progress of disassembly sequencing planning in four major aspects:product disassembly modeling methods,mathematical programming methods,artificial intelligence methods,and uncertainty *** survey should stimulate readers to be engaged in the research,development and applications of disassembly and remanufacturing methodologies in the Industry 4.0 era.

关键词： Artificial intelligence(AI) disassembly sequence planning(DSP) intelligent optimization modeling methods multiobjective optimization single-objective optimization uncertainty.

Development of Fixture Layout Optimization for Thin-Walled Parts:A Review

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 15-39页

作者： Changhui Liu Jing Wang Binghai Zhou Jianbo Yu Ying Zheng Jianfeng Liu School of Mechanical Engineering Tongji UniversityShanghai 201804China Shanghai Jiaotong University Shanghai 200240China Shanghai Waigaoqiao Shipbuilding Co. Ltd.Shanghai 200137China

An increasing number of researchers have researched fixture layout optimization for thin-walled part assembly during the past ***,few papers systematically review these *** analyzing existing literature,this paper summarizes the process of fixture layout optimization and the methods *** process of optimization is made up of optimization objective setting,assembly variation/deformation modeling,and fixture layout *** paper makes a review of the fixture layout for thin-walled parts according to these three ***,two different kinds of optimization objectives are *** usually consider in-plane variations or out-of-plane deformations when designing ***,modeling methods for assembly variation and deformation are divided into two categories:Mechanism-based and data-based *** common methods are discussed *** that,optimization algorithms are reviewed *** are two kinds of optimization algorithms:Traditional nonlinear programming and heuristic ***,discussions on the current situation are *** research direction of fixture layout optimization in the future is discussed from three aspects:Objective setting,improving modeling accuracy and optimization ***,a new research point for fixture layout optimization is *** paper systematically reviews the research on fixture layout optimization for thin-walled parts,and provides a reference for future research in this field.

关键词： Thin-walled parts Assembly quality Fixture layout optimization modeling methods Optimization algorithms

Establishing a rat model of spastic cerebral palsy by targeted ethanol injection

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Neural Regeneration Research 2013年第34期8卷 3255-3262页

作者： Yadong Yu Liang Li Xinzhong Shao Fangtao Tian Qinglu Sun Department of Hand Surgery the Third Hospital of Hebei Medical University

Spastic cerebral palsy is generally considered to result from cerebral cortical or pyramidal tract damage. Here, we precisely targeted the left pyramidal tract of 2-month-old Sprague-Dawley rats placed on a stereotaxic instrument under intraperitoneal anesthesia. Based on the rat brain stereotaxic map, a 1-mm hole was made 10 mm posterior to bregma and 0.8 mm left of sagittal suture. A microsyringe was inserted perpendicularly to the surface of the brain to a depth of 9.7 mm, and 15 wL of ethanol was slowly injected to establish a rat model of spastic cerebral palsy. After modeling, the rats appeared to have necrotic voids in the pyramidal tract and exhibited typical signs and symptoms of flexion spasms that lasted for a long period of time. These findings indicate that this is an effective and easy method of establishing a rat model of spastic cerebral palsy with good reproducibility. Ethanol as a chemical ablation agent specifically and thoroughly damages the py- ramidal tract, and therefore, the animals display flexion spasms, which are a typical symptom of the disease.

关键词： neural regeneration brain injury spastic cerebral palsy animal models ethanol pyramidal tractstereotaxic instrument targeted injection modeling methods neuroregeneration