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Clinical observation of biomimetic mineralized collagen artificial bone putty for bone reconstruction of calcaneus fracture

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Regenerative Biomaterials 2018年第2期5卷 61-67页

作者： Yong-Xiong Pan Guang-Gang Yang Zhong-Wan Li Zhong-Min Shi Zhan-Dong Sun Department of Foot and Ankle Orthopedics Guangzhou Orthopedic HospitalGuangzhou 510045China Department of Foot and Ankle Orthopedics Shanghai Sixth People’s HospitalShanghai 200233China

This study investigated clinical outcomes of biomimetic mineralized collagen artificial bone putty for bone reconstruction in the treatment of calcaneus *** cases of calcaneal fractures surgically treated with open reduction and internal fixation in our hospital from June 2014–2015 were chosen and randomly divided into two groups,including 30 cases treated with biomimetic mineralized collagen artificial bone putty as treatment group,and 30 cases treated with autogenous ilia as control *** average follow-up time was 17.263.0 *** results showed that the surgery duration and postoperative drainage volume of treatment group were significantly lower than control group;there were no statistically significant differences in the fracture healing time,American Orthopaedic Foot and Ankle Society scores at 3 and 12 months after surgery,Bo¨hler’s angle,Gissane’s angle and height of calcaneus between the two *** were no significant differences in wound complication and reject reaction between the two groups,while significant difference in donor site *** a conclusion,the implantation of biomimetic mineralized collagen artificial bone putty in the open reduction of calcaneal fracture resulted in reliable effect and less complications,which is suitable for clinical applications in the treatment of bone defect in calcaneal fractures.

关键词： calcaneus fracture mineralized collagen artificial bone putty bone substitute bone grafting

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