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Facial reanimation with interposition nerve graft or masseter nerve transfer:a comparative retrospective study

Neural Regeneration Research 2022年第5期17卷 1125-1130页

作者： Wen-Jin Wang Wei-Dong Zhu Mathias Tremp Gang Chen Zhao-Yan Wang Hao Wu Wei Wang Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Otolaryngology Head and Neck Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases ShanghaiChina Ear Institute Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Plastic ReconstructiveAesthetic and HandsurgeryUniversity Hospital BaselBaselSwitzerland

Both interposition nerve grafts and masseter nerve transfers have been successfully used for facial reanimation after irreversible injuries to the cranial portion of the facial ***,no comparative study of these two procedures has yet been *** this two-site,twoarm,retrospective case review study,32 patients were *** these,17 patients(eight men and nine women,mean age 42.1 years)underwent interposition nerve graft after tumor extirpation or trauma between 2003 and 2006 in the Ear Institute,School of Medicine,Shanghai Jiao Tong University,China,and 15 patients(six men and nine women,mean age 40.6 years)underwent masseter-to-facial nerve transfer after tumor extirpation or trauma between November 2010 and February 2016 in Shanghai Ninth People's Hospital,*** patients achieved House-Brackmann III recovery after masseter nerve repair than interposition nerve graft repair(15/15 vs.12/17).The mean oral commissure excursion ratio was also higher in patients who underwent masseter nerve transfer than in patients subjected to an interposition nerve *** findings suggest that masseter nerve transfer results in strong oral commissure excursion,avoiding obvious synkinesis,while an interposition nerve graft provides better resting *** study was approved by the Institutional Ethics Committee,Shanghai Ninth People's Hospital,China(approval ***9 H-2019-T332-1)on December 12,2019.

关键词： facial palsy facial reanimation facial symmetry House-Brackmann score interposition masseter nerve nerve graft oral commissure excursion resting symmetry synkinesis

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Is there a primitive reflex residue underlying Marcus Gunn Syndrome? Rat electrophysiology

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International Journal of Ophthalmology(English edition) 2020年第1期13卷 29-35页

作者： Ying Qiao Hou-Cheng Liang Jing-Dong Zhang Pi-Fu Luo An-Le Su Ting Zhang Hong-Na Zhu Xi’an First Hospital Key Clinic Ophthalmology LabShaanxi Province Eye Research InstituteXi’an 710002Shaanxi ProvinceChina Xi’an BRIGHT Eye Hospital 234 West Youyi RoadXi’an 710068Shaanxi ProvinceChina Department of Ophthalmology Affiliated HospitalXi’an Jiaotong UniversityXi’an 710002Shaanxi ProvinceChina Department of Pathology University of Iowa College of MedicineIowa CityIA 52242USA

AIM: To make an electrophysiological demonstration of a possible jaw muscle afferents-oculomotor neural pathway that was proposed by our previous works on rats, which substantiates an early "release hypothesis" on pathogenesis of human Marcus Gunn Syndrome(MGS). METHODS: Extracellular unit discharge recording was applied and both orthodromic and spontaneous unitary firing were recorded in the oculomotor nucleus(III), and the complex of pre-oculomotor interstitial nucleus of Cajal and Darkschewitsch nucleus(INC/DN), following electric stimulation of the ipsilateral masseter nerve(MN) in rats. RESULTS: Extracellular orthodromic unit discharges, with latencies of 3.7±1.3 and 4.7±2.9 ms, were recorded unilaterally in the III, and the INC/DN neurons, respectively. Spontaneous unit discharges were also recorded mostly in the INC/DN and less frequently in the III. Train stimulation could prompt either facilitation or inhibition on those spontaneous unit discharges. The inhibition pattern of train stimulation on the spontaneous discharging was rather different in the III and INC/DN. A slow inhibitory pattern in which spontaneous firing rate decreased further and further following repeated train stimulation was observed in the III. While, some high spontaneous firing rate units, responding promptly to the train stimuli with a short-term inhibition and recovered quickly when stimuli are off, were recorded in the INC/DN. However, orthodromic unit discharge was not recorded in the III and INC/DN in a considerable number of experiment animals. CONCLUSION: A residual neuronal circuit might exist in mammals for the primitive jaw-eyelid reflex observed in amphibians, which might not be well-developed in all experimental mammals in current study. Nonetheless, this pathway can be still considered as a neuroanatomic substrate for development of MGS in some cases among all MGS with different kind of etiology.

关键词： masseter nerve single unit discharge oculomotor nucleus pre-oculomotor neurons interstitial nucleus of Cajal/Darkschewitsch nucleus Marcus Gunn Syndrome

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颅内段面神经损伤后修复的新技术:咬肌神经-面神经吻合术(英文)

颅内段面神经损伤后修复的新技术:咬肌神经-面神经吻合术(英文)

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中华医学会第10届全国显微外科学术会议暨世界首例断肢再...

作者：王炜上海交通大学医学院附属第九人民医院整复外科

Background:masseter-to-facial nerve transfer is a newly procedure for those patients who had acquired proximal injury to the facial *** article identifies its efficiency associated with minimal morbidities. Methods:From November,2010,to March,2012,16 patients underwent this procedure at 2 to 19 months (mean 10.63±4.63 months) after resection of cerebellopontine angle(CPA) *** patients’ ages varied from 22 to 70 years(mean 34.7±15.4 years).Using Terzis’ and Mehta’s scale,smile outcomes and

关键词： facial nerve masseter nerve facial reanimatinn

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