检索结果-南通市图书馆

The Study of Diversities of marine microbes in China

Bulletin of the Chinese Academy of Sciences 2010年第4期24卷 228-234页

作者： ZHANG Si ZHANG Changsheng TIAN Xinpeng WANG Fazuo LI Jie South China Sea Institute of Oceanology CAS 510301 Guangzhou

The oceans account for 71% of the Earth’s surface and are rich in the most advantageous and characteristic resources of marine microbes. The research on diversity is the key point for exploring and exploiting marine microbial resources. Giving attention to species diversity and genetic diversity of marine microbes, discovering novel metabolites with multiple functions, revealing key secondary metabolic process and the main regulation mechanisms in marine microbes, and developing a new technology of biosynthesis, are the important foundation for discovering innovative drugs and developing functional products with characteristics. The present paper has reviewed the recent advances in the four research areas of marine microbial species diversity, genetic diversity, chemical diversity and metabolic diversity in China.

关键词： marine microbes diversity species genetic chemical metabolic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antimicrobial metabolites from marine microorganisms

引用

Chinese Journal of Natural Medicines 2016年第2期14卷 101-116页

作者： Prasanna Habbu Vijayanand Warad Rajesh Shastri Smita Madagundi Venkatrao H. kulkarni Postgraduate Department of Pharmacognosy & Phytochemistry SET's College of Pharmacy Dharwad 580002 Karnatakalndia Department of Pharmacognosy and Phytochemistry Sridevi College of Pharmacy Mangalore 575006 Karnataka India" Postgraduate Department of Pharmacology SET's College of Pharmacy Dharwad 580002 Karnataka India

marine ecological niches have recently been described as "particularly promising" sources for search of new antimicrobials to combat antibiotic-resistant strains of pathogenic microorganisms. marine organisms are excellent sources for many industrial products, but they are partly explored. Over 30 000 compounds have been isolated from marine sources. Bacteria, fungi, and cyanobacteria obtained from various marine sources secret several industrially useful bioactive compounds, possessing antibacterial, antifungal, and antimycobacterial activities. Sustainable cultivation methods for promising marine organisms and biotechnological processes for selected compounds can be developed, along with the establishment of biosensors for monitoring the target compounds. The semisynthetic modifications of marine-based bioactive compounds produce their new derivatives, structural analogs and mimetics that could serve as novel lead compounds against resistant pathogens. The present review focuses on promising antimicrobial compounds isolated from marine microbes from 1991-2013.

关键词： Antibacterial metabolites Antifungal metabolites marine microbes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anti-tumour Secondary Metabolites from Coral-derived Bacterium L-4 of South China Sea

Anti-tumour Secondary Metabolites from Coral-derived Bacteri...

引用

中国化学会第9届天然有机化学学术会议

作者： Qiong Guo,Ling-Fang Lei,Xao-Jie Chen,Yun Deng,Cui-Xian Zhang~* School of Chinese Materia Medica,Guangzhou University of TCM,Guangzhou,510006

＜正＞Objective In order to develop the marine organic resource,and based on OSMAC strategy,research anti-tumor activity secondary metabolites from coral -derived bacteria L-4 of the South China *** Explore different media to the influence of marine-derived cultivatable microbes by TLC and *** compounds from the ethyl acetate extracts of bacteria L-4 were isolated by silica gel column,Sephadex LH-20 column chromatography and HPLC *** were identified by the physicochemical properties and spectral analysis（1D,2D NMR and MS et.）.Results Different media obviously effect the secondary metabolites,and produce different substances which were not present in the sole cultivate by TLC and *** compounds were isolated from the ethyl acetate extracts of marine bacteria L-4 isolated coral of South China *** were identified as cyclo （Trp-Ala）,cyclo（Tyr-Gly）,Cyclo（Gly-Phe）,cyclo（Gly-Pro）,cyclo（Ala-Val）,cyclo （Gly-Ala）,Cyclo（Ala-Tyr）,Cyclo（Val-Phe）,Cyclo（A1a-Phe）,Cyclo（Gly-Leu）,Cyclo （Ala-Leu）,whcih are also *** compounds are *** one was composed of four amino acids:tyrosine,glycine,serine,alanine by NMR and HR-ESI-MS, and was a new *** Change marine-derived cultivatable microbes growth media to stimulate more high activity novel structure is worthy of *** of the compounds were isolated from the marine bacterium L-4 for the first time.

关键词： OSMAC marine microbes secondary metabolites coral-derived bacteria L-4 cyclo-dipeptides structure identification

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：