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Characteristics of macular microvasculature before and after idiopathic macular hole surgery

International Journal of Ophthalmology(English edition) 2022年第1期15卷 98-105页

作者： Dan Cheng Ji-Wei Tao Xue-Ting Yu Yi-Qi Chen Mei-Xiao Shen Min-Hui Wu Jia-Feng Yu Heng-Li Lian Zhe Lu Li-Jun Shen The Affiliated Eye Hospital of Wenzhou Medical University Hangzhou 310000Zhejiang ProvinceChina

AIM:To evaluate the macular microvasculature before and after surgery for idiopathic macular hole(MH)and the association of preoperative vascular parameters with postoperative recovery of visual acuity and ***:Twenty eyes from 20 patients with idiopathic MH were *** coherence tomography angiography(OCTA)images were obtained before,2 wk,1,and 3 mo after vitrectomy with internal limiting membrane *** foveal avascular zone(FAZ)area and perimeter and regional vessel density(VD)in both layers were compared according to the 3-month best-corrected visual acuity(BCVA).RESULTS:The BCVA improved from 0.98±0.59(log MAR,Snellen 20/200)preoperatively to 0.30±0.25(Snellen 20/40)at 3 mo *** preoperative deep VD was smaller and the FAZ perimeter was larger in the 3-month BCVA<20/32 group(all P<0.05).A significant reduction was observed in FAZ parameters and all VDs 2 wk *** for deep perifoveal VD,all VDs recovered only to their preoperative *** postoperative FAZ parameters were lower during *** in preoperative deep VDs were correlated with worse postoperative BCVA(Pearson’s r=-0.667 and-0.619,respectively).A larger FAZ perimeter(Spearman’s r=-0.524)and a lower deep perifoveal VD preoperatively(Pearson’s r=0.486)were associated with lower healing ***:The status of the deep vasculature may be an indicator of visual acuity in patients with a closed *** for the deep perifoveal region,VD recovers only to preoperative levels.

关键词： macular microvasculature macular hole vitreoretinal surgery optical coherence tomography angiography

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Optical coherence tomography in ischemic optic neuropathy

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Annals of Eye Science 2020年第1期5卷 35-44页

作者： Masoud Aghsaei Fard Hossein Ghahvehchian Prem S.Subramanian Farabi Eye Hospital Tehran University of Medical SciencesTehranIran Sue Anschutz-Rodgers UCHealth Eye Center AuroraCOUSA Departments of Ophthalmology Neurologyand NeurosurgeryUniversity of Colorado School of MedicineAuroraCOUSA

Ischemic optic neuropathies are among the most common causes of sudden vision loss,especially in patients over age *** cause and prognosis of these disorders,and in particular non-arteritic anterior ischemic optic neuropathy,is poorly understood,and treatments remain poor in terms of restoring or preserving *** coherence tomography(OCT)and OCT angiography have allowed us to identify early and late structural changes in the optic nerve head and retina that may assist in predicting visual outcomes and may lead to greater understanding of pathogenesis and thus the development of effective medical interventions.

关键词： Ischemic optic neuropathy optical coherence tomography angiography(OCT-A) visual field defect macular microvasculature

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