检索结果-南通市图书馆

Gene expression, transcription factor binding and histone modification predict leaf adaxial-abaxial polarity related genes

引用

Horticultural Plant Journal 2024年第4期10卷 971-982页

作者： Wei Sun Zhicheng Zhang Guusje Bonnema Xiaowu Wang Aalt Dirk Jan van Dijk State Key Laboratory of Vegetable Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural Sciences Sino-Dutch Joint Lab of Vegetable Genomics Bioinformatics Group Wageningen University and Research Plant Breeding Wageningen University and Research Biosystems Data Analysis Swammerdam Institute for Life SciencesUniversity of Amsterdam

leaf adaxial-abaxial(ad-abaxial) polarity is crucial for leaf morphology and function, but the genetic machinery governing this process remains unclear. To uncover critical genes involved in leaf ad-abaxial patterning, we applied a combination of in silico prediction using machine learning(ML) and experimental analysis. A Random Forest model was trained using genes known to influence ad-abaxial polarity as ground truth.Gene expression data from various tissues and conditions as well as promoter regulation data derived from transcription factor chromatin immunoprecipitation sequencing(ChIP-seq) was used as input, enabling the prediction of novel ad-abaxial polarity-related genes and additional transcription factors. Parallel to this, available and newly-obtained transcriptome data enabled us to identify genes differentially expressed across leaf ad-abaxial sides. Based on these analyses, we obtained a set of 111 novel genes which are involved in leaf ad-abaxial specialization. To explore implications for vegetable crop breeding, we examined the conservation of expression patterns between Arabidopsis and Brassica rapa using single-cell transcriptomics. The results demonstrated the utility of our computational approach for predicting candidate genes in crop species. Our findings expand the understanding of the genetic networks governing leaf ad-abaxial differentiation in agriculturally important vegetables,enhancing comprehension of natural variation impacting leaf morphology and development, with demonstrable breeding applications.

关键词： Machine learning leaf polarity Arabidopsis thaliana Brassica rapa Transcription factor

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

ASYMMERTIC LEAVES1/2 ENHANCER7,a novel gene required for BREVIPEDICELLUS repression and leaf adaxial-abaxial polarity establishment in Arabidopsis

ASYMMERTIC LEAVES1/2 ENHANCER7,a novel gene required for BRE...

引用

上海市植物生理学会成立三十周年庆祝活动暨第三届上海市植...

作者： Zhenhuan Yuan Hua Wang Guang Li Xiaozhen Yao Dexian Luo Minhuan Zeng Hai Huang Xiaofeng Cui* National Laboratory of Plant Molecular Genetics Shanghai Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 300 Fenglin Road Shanghai 200032 China

＜正＞The Arabidopsis ASYMMETRIC LEAVES1 and 2 （AS1 and AS2） genes, both encoding transcription factors, play important roles in leaf morphogenesis. AS1 and AS2 are known to

关键词： Arabidopsis leaf polarity as1/2 enhancer7 BREVIPEDICELLUS repression

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

From genes to networks: The genetic control of leaf development

引用

Journal of Integrative Plant Biology 2021年第7期63卷 1181-1196页

作者： Hongfeng Wang Fanjiang Kong Chuanen Zhou The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266101China Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006China

Substantial diversity exists for both the size andshape of the leaf,the main photosynthetic organofflowering plants.The two major forms of leaf aresimple leaves,in which the leaf blade is undivided,and compound leaves,which comprise severalleaflets.Leaves form at the shoot apical meristemfrom a group of undifferentiated cells,whichfirstestablish polarity,then grow and differentiate.Each of these processes is controlled by a com-bination of transcriptional regulators,microRNAsand phytohormones.The present review docu-ments recent advances in our understanding ofhow these various factors modulate the develop-ment of both simple leaves(focusing mainly on themodel plantArabidopsis thaliana)and compoundleaves(focusing mainly on the model legumespeciesMedicago truncatula).

关键词： compound leaves genetic network leaf develop-ment leaf polarity simple leaves

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：