检索结果-南通市图书馆

H3K36 Methylation Is involved in Promoting Rice Flowering

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2013年第3期6卷 975-977页

作者： Pengfei Sui Jinlei Shi xueying Gao Wen-Hui Shen Aiwu -Dong State Key Laboratory of Genetic Engineering Institute of Plant Biology Department of Biochemistry School of Life Sciences Fudan University Shanghai 200433 RR. China Institut de Biologie Moleculaire des Plantes du CNRS Universite de Strasbourg 12 rue du General Zimmer 67084 Strasbourg Cedex France

Dear Editor, Histone H3 lysine 36 （H3K36） methylation is a conserved epigenetic mark in all eukaryotes （Berr et al., 2011; Wagner and Carpenter, 2012）. Reverse genetic analysis in Arabidopsis had uncovered a crucial role of H3K36 di- and tri-methylation （H3K36me2 and H3K36me3） in flowering-time regulation （reviewed in Berr et al., 2011）.

关键词： H3K36 Methylation involved

OsGRAS19 May Be a Novel Component involved in the Brassinosteroid Signaling Pathway in Rice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2013年第3期6卷 988-991页

作者： LishengChen Guosheng Xiong Xia Cui Meixian Yan Ting Xu Qian Qian Yongbiao Xue Jiayang Li Yonghong Wang State Key Laboratory of Plant Genomics and National Center for Plant Gene Research Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China Present address: Molecular Cellular and Developmental Biology University of Michigan Ann Arbor MI 48105 USA State Key Laboratory of Rice Biology China National Rice Research Institute Chinese Academy of Agricultural Sciences Hangzhou 310006 China State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China

Dear Editor, The brassinosteroid （BR） signaling pathway has been well elucidated in Arabidopsis. The identification of BR-signaling components in rice suggested that the primary pathway is conserved in both dicot a... 详细信息

关键词： OsGRAS19 Component involved

Selection Model of Optional Parts in Suppliers involved in New Product Development

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

武汉理工大学学报 2006年第S1期28卷 156-161页

作者： MU Lifeng,TANG Jiafu,PAN Zhendong,HAN Yi (School of Information Science & Engineering,Northeastern University,Shenyang 110004,China) School of Information Science & Engineering Northeastern UniversityShenyang 110004China

Quality function deployment (QFD),which can translate efficiently customer requirement (CRs) into technical attributes (TAs),is widely used in new product development (NPD) as an efficient customer-driven approach. After lots of QFD application is applied in manufacturing fields,it was proved that without considering suppliers involved,it is difficult to get precise and satisfying results in each process of QFD,particularly part deployment. The paper will address the issues of a model of optional parts selection in suppliers involved in part deployment process. Further,it has been applied to an ERP system reconstruction and updating problem as an illustration.

关键词： new product development suppliers involved quality function deployment part deployment customer requ

The Prognostic Value of Minimally involved Melanoma Sentinel Lymph Nodes

在线全文

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2013年第10期4卷 1490-1498页

作者： Alend Saadi Didier Roulin Essia Saiji Hanifa Bouzourene Nicolas Demartines Maurice Matter Department of Visceral Surgery Centre Hospitalier Universitaire Vaudois Lausanne Switzerland University Institute of Pathology Centre Hospitalier Universitaire Vaudois Lausanne Switzerland

Background: Sentinel node (SLN) status is the most important prognostic factor for early-stage melanoma patients. It will influence follow-up and may change therapy. Positive SLNs present different degrees of involvement so that subgroups of patients may have minimal SLN invasion. The aim of this study was to evaluate survival in subgroups with minimally involved SLNs and to compare them to negative SLN patients. Method: SLN biopsy was performed in 499 consecutive clinically N0 patients between 1997 and 2008. Following updated recommendations from the Melanoma Group of the European Organization of Research and Treatment of Cancer, degrees of SLN involvement were fully reassessed for two anatomopathological parameters: tumour burden according to Rotterdam criteria (1.0 mm) and microanatomic location according to Dewar (subcapsular, combined subcapsular and parenchymal, parenchymal, multifocal, or extensive). Minimally involved SLNs were defined as those with tumor burden involved SLNs, there were 21 with tumour burden involved sub-groups were not predictive for NSLN negativity. Conclusion: Rotterdam’s tumour burden stratification is an easy and useful progn

关键词： Metastatic Melanoma Sentinel Node Minimally involved

3-73 Both p21 and Cytoskeleton are involved in Radiation Induced Cell Cycle Arrest in Uveal Melanoma 92-1 Cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

IMP & HIRFL Annual Report 2014年第1期 166-166页

作者： Zhang Xurui Wang Jufang 不详

One of the main engines that drive cellular transformation is the loss of proper control of the cell cycle. Thecyclin-dependent kinase inhibitor p21 (also known as p21WAF1/Cip1) promotes cell cycle arrest in response tomany stimuli[1]. Our recent study[2;3] showed that a global and stable cell cycle block was established in 92-1 cellsafter 10 Gy of X-ray and carbon ion irradiation and cells underwent senescence 5 d later. p21 was detected at highlevels from 4 h to 5 d after irradiation in these cells, which implied that p21 played a crucial role in cellular responseto irradiation.

关键词： p21 Cytoskeleton involved

Clinical features and treatment outcomes of primary ocular adnexal mucosa-associated lymphoid tissue lymphoma: a single center retrospective analysis of 64 patients in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2019年第11期12卷 1731-1736页

作者： Hui Yu Yu-Xin Du Zhen-Chang Sun Xiao-Rui Fu Nan Tan Wei-Feng Gong Ming-Zhi Zhang Department of Oncology Zhengzhou University First Affiliated HospitalLymphoma Diagnosis and Treatment Center of Henan ProvinceZhengzhou 450052Henan ProvinceChina Department of Ophthalmology Zhengzhou University First Affiliated HospitalZhengzhou 450052Henan ProvinceChina

AIM: To investigate the clinical features, treatment and prognosis of primary ocular adnexal mucosa-associated lymphoid tissue lymphoma(POAML).METHODS: A retrospective analysis was performed on 64 patients with POAML who were admitted to the First Affiliated Hospital of Zhengzhou University from January 2006 to December ***: With a median follow-up of 61 mo(range, 2-156 mo), estimated overall survival(OS) rate and progressionfree survival(PFS) rate at 10 y reached 94.5% and 61.5%, respectively. Median OS time and PFS time were not reached. During this period, only 3 patients died, but none of them died directly due to disease progression. One patient(1.6%) developed transformation to diffuse large B-cell lymphoma(DLBCL). Of the 56 patients achieved complete remission after first-line treatment, 5(8.9%) developed local and/or systemic relapse eventually. Patients ≥60 y had significantly shorter PFS than younger patients(P=0.01). For patients with early stages(Ann Arbor stage I and stage II), univariate analysis confirmed that radiotherapydose lower than 32 Gy were independently associated with shorter PFS(P=0.04). Other factors including gender, bone marrow involvement, the initial location of the disease, and the laterality were not associated with ***: The data from our center indicate that POAML has a slow clinical progression and has an excellent clinical outcome. Patients with POAML harbor a continual risk of relaps and transformation to aggressive subtype of lymphoma.

关键词： primary ocular adnexal MALT lymphoma mucosa-associated lymphoid tissue involved site radiation therapy immunochemotherapy

Understanding human diseases using Drosophila

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2019年第4期46卷 155-156页

作者： Jun-Yuan Ji Chun Han Wu-Min Deng Department of Molecular and Cellular Medicine College of MedicineTexas A&M University Health Science CenterCollege Station Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics Cornell University Department of Biological Science Florida State University

One of the major goals of biomedical research is to elucidate the causal relationships of critical factors involved in the initiation and progression of human diseases at the molecular and cellular levels. This knowledge is required for developing effective treatments for major diseases including cancer, cardiovascular and metabolic diseases, as well as neurodegenerative diseases and neurological disorders. Because of their phylogenetic representations and relative ease of experimental manipulation, model organisms such as the budding yeast (Saccharomyces cerevisiae), the nematode worm (Caenorhabditis elegans), the fruit fly (Drosophila melanogaster'), the thale cress (Arabidopsis thaliana), the zebrafish (Danio rerio'), the frog (Xenopus laevis), and the mouse (Mus musculus}, have been extensively studied over the past century (Hedges, 2002;Muller and Grossniklaus, 2010;Dietrich et al., 2014).

关键词： biomedical research causal relationships critical factors involved

Copper Ion Elicits Defense Response in Arabidopsis thaliana by Activating Salicylate- and Ethylene-Dependent Signaling Pathways

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2015年第10期8卷 1550-1553页

作者： Haifeng Liu Baogang Zhang Tao Wu Yiliang Ding Xinhua Ding Zhaohui Chu State Key Laboratory of Crop Biology Shandong Provincial Key Laboratory of Agricultural Microbiology Shandong Agricultural University Tai an 271018 Shandong PR China Department of Cell and Developmental Biology John Innes Centre Norwich NR4 7UH UK These authors contributed equally to this article.

Dear Editor,Copper, one of the micronutrients, is essential during vegetative growth, development, and multiplication of plants （Penarrubia et al., 2010）. Copper is widely known for its application in fungicides and bactericides in agriculture since the late 19th century, for example, in the well-known Bordeaux mixture. Previous studies show that the mechanisms of copper ionsmediated antimicrobial activity involve either inhibition of the enzymes participated in fungal spore germination or direct toxicity on the growth of bacteria. Two studies also show that excessive copper is able to activate mitogen-activated protein （MAP） kinase signaling and upregulate defense-related genes in rice （Yeh et al., 2003; Sudo et al., 2008）. In addition, the application of copper was found to suppress the spread of Xanthornonas oryzae pv. oryzae PXO99A strain in rice （Yuan et al., 2010）. These previous studies imply that copper might be involved in regulating the defense response in plants.

关键词： involved regulating response

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

谈单位犯罪及其相关问题

河南警察学院学报 1999年第3期19卷 55-56页

作者：贾建新

我国首次确认单位可以成为犯罪主体并应承担相应刑事责任的法律，是１９８７年颁布的《海关法》第４７条第３款中的有关规定，其后又有４０余部单行刑事法律也对单位犯罪陆续作了规定。但就总体而言，对单位犯罪的定义是不明确的，规定... 详细信息

我国首次确认单位可以成为犯罪主体并应承担相应刑事责任的法律，是１９８７年颁布的《海关法》第４７条第３款中的有关规定，其后又有４０余部单行刑事法律也对单位犯罪陆续作了规定。但就总体而言，对单位犯罪的定义是不明确的，规定也过于分散。１９９７年３月１４日通...

关键词：】:Lawyers Getting involved in Advance Existent problems Improvement