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Multimodal intravascular imaging technology for characterization of atherosclerosis

Journal of Innovative Optical Health Sciences 2020年第1期3卷 82-96页

作者： Yan Li Jason Chen Zhongping Chen Beckman Laser Institute University of CaliforniaIrvine 1002 Health Sciences RoadIrvineCA 92617 USA Department of Biomedical Engineering University of California IrvineCA 92697-2700 USA

Early detection of vulnerable plaques is the critical step in the prevention of acute coronary ***,composition,and mechanical property of a coronary artery have been demonstrated to be the key characteristics for the identification of vulnerable *** intravascular multimodal imaging technologies providing co-registered simultaneous images have been developed and applied in clinical studies to improve the characterization of *** this paper,the authors review the present system and probe designs of representative intra-vascular multimodal *** addition,the scientific innovations,potential limitations,and future directions of these technologies are also discussed.

关键词： Multimodal intravascular imaging photoacoustic ultrasound optical coherence tomography near-infrared fluorescence spectroscopy atherosclerosis imaging probe

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Perspectives on the rational integration of intravascular imaging and physiology into the current cath lab environment

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Chinese Medical Journal 2013年第6期126卷 1013-1018页

作者： Gary S. Mintz Chief Medical Officer Cardiovascular Research Foundation 111 East 59th Street-llth Floor New York NY 10022 USA

It is now more than two decades since Nico Pijls and Bernard DeBruyne introduced fractional flow reserve （FFR） as a way to assess stenosis severity in the catheterization laboratory and since Paul Yock invented grayscale intravascular ultrasound （IVUS） that then spawned many second-generation intravascular imaging techniques such as （1） Virtual histology-IVUS （VH-IVUS） that uses both amplitude and radiofrequency ultrasound information to classify plaque as necrotic core,

关键词： intravascular imaging physiology cath lab environment

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Pencil-beam scanning catheter for intracoronary optical coherence tomography

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Opto-Electronic Advances 2022年第3期5卷 69-75页

作者： Jiqiang Kang Rui Zhu Yunxu Sun Jianan Li Kenneth K.Y.Wong School of Electronic and Information Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China International Graduate School at Shenzhen Tsinghua UniversityShenzhen 518055China Shenzhen Vivolight Medical Device&Technology Co. Ltd.Shenzhen 518055China State Key Laboratory of Transient Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China Department of Electrical and Electronic Engineering The University of Hong KongPokfulam RoadHong KongChina Advanced Biomedical Instrumentation Centre Hong Kong Science ParkShatinNew TerritoriesHong KongChina

Current gradient-index(GRIN)lens based proximal-driven intracoronary optical coherence tomography(ICOCT)probes consist of a spacer and a GRIN lens with large gradient *** design provides great flexibility to control beam profiles,but the spacer length should be well controlled to obtain desired beam profiles and thus it sets an obstacle in mass catheter ***,although GRIN lens with large gradient constant can provide tight focus spot,it has short depth of focus and fast-expanded beam which leads to poor lateral resolution for deep *** this paper,a type of spacer-removed probe is demonstrated with a small gradient constant GRIN *** design simplifies the fabrica-tion process and is suitable for mass *** output beam of the catheter is a narrow nearly collimated light beam,referred to as pencil beam *** full width at half maximum beam size varies from 35.1μm to 75.3μm in air over 3-mm *** design principles are elaborated with probe/catheter fabrication and performance *** in vivo imaging of the catheter was verified by a clinical ICOCT *** results prove that this novel pencil-beam scanning catheter is potentially a good choice for ICOCT systems.

关键词： optical coherence tomography endoscopic imaging intravascular imaging fiber optics imaging

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A case report of significant progression after FFR-guided deferred PCI

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Journal of Geriatric Cardiology 2020年第10期17卷 649-652页

作者： Cheng-Duo ZHANG Xin-Ye XU Li-Jun GUO Wei GAO Department of Cardiology Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesBeijingChina

In recent years,the use of coronary functional evaluation derived by fractional flow reserve(FFR)to guide percutaneous coronary intervention(PCI)treatment has been recommended by several mainstream ***,FFR>0.80 in cor... 详细信息

关键词： Delayed lesion intervention Fractional flow reserve Intermediate lesion intravascular imaging Unstable plaques

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