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Increased regional homogeneity in internet addiction disorder： a resting state functional magnetic resonance imaging study

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Chinese Medical Journal 2010年第14期123卷 1904-1908页

作者： LIU Jun GAO Xue-ping Isoken Osunde LI Xin ZHOU Shun-ke ZHENG Hui-rong LI Ling-jiang Institute of Mental-Health Department of Radiology the Second Xiangya Hosipital Central South University Changsha Hunan 410011 China Wayne State University School of Medicine Detroit MI 48202 USA

Background internet addition disorder （lAD） is currently becoming a serious mental health problem among Chinese adolescents. The pathogenesis of lAD, however, remains unclear. The purpose of this study applied regional homogeneity （ReHo） method to analyze encephalic functional characteristic of lAD college students under resting state. Methods Functional magnetic resonanc image （fMRI） was performed in 19 lAD college students and 19 controls under resting state. ReHo method was used to analyze the differences between the average ReHo in two groups. Results The following increased ReHo brain regions were found in lAD group compared with control group： cerebellum, brainstem, right cingulate gyrus, bilateral parahippocampus, right frontal lobe （rectal gyrus, inferior frontal gyrus and middle frontal gyrus）, left superior frontal gyrus, left precuneus, right postcentral gyrus, right middle occipital gyrus, right inferior temporal gyrus, left superior temporal gyrus and middle temporal gyrus. The decreased ReHo brain regions were not found in the lAD group compared with the control group. Conclusions There are abnormalities in regional homogeneity in lAD college students compared with the controls and enhancement of synchronization in most encephalic regions can be found. The results reflect the functional change of brain in lAD college students. The connections between the enhancement of synchronization among cerebellum, brainstem, limbic lobe, frontal lobe and apical lobe may be relative to reward pathways.

关键词： internet addiction disorder resting state regional homogeneity functional magnetic resonance image

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Decreased frontal lobe function in people with internet addiction disorder

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Neural Regeneration Research 2013年第34期8卷 3225-3232页

作者： Jun Liu Fatema Esmail Lingjiang Li Zhifeng Kou Weihui Li Xueping Gao Zhiyuan Wang Changlian Tan Yan Zhang Shunke Zhou Department of Radiology Second Xiangya Hosipital Central South University School of Public Administration Central South University Wayne State University Detroit Medical Center Institute of Mental Health Central South University Hunan Provincial Tumor Hospital

In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho- line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with internet addiction disorder.

关键词： neural regeneration internet addiction disorder internet gaming addiction magnetic resonanceimaging magnetic resonance spectroscopy N-acetylaspartate choline-containing compounds creatine grants-supported paper neuroregeneration

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Effect of electro-acupuncture combined with psychological intervention on mental symptoms and P50 of auditory evoked potential in patients with internet addiction disorder

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Journal of Traditional Chinese Medicine 2017年第1期37卷 43-48页

作者： Li Hui Jin Rongjiang Yuan Kezhu Zheng Bo Zheng Zhong Luo Ying Ye Hua Huang Bingjie Zhu Tianmin School of Medicine Chengdu UniversityChengdu 610106China College of Health and Rehabilitation Chengdu University of Traditional Chinese MedicineChengdu 610075China West China School of Medicine Sichuan UniversityChengdu 610041China Mental Health Center West China Hospital of Sichuan UniversityChencjdu 610041China Rehabilitation Center of Sichuan Limbs Disability Chengdu 610021China

OBJECTIVE: To observe the therapeutic effects of electro-acupuncture(EA) combined with psychological intervention on the symptom of somzatization or obsession and mental symptom of depression or anxiety and P50 of Auditory Evoked Potential(AEP) on internet addiction disorder(IAD).METHODS: One hundred and twenty cases of IAD were randomly divided into an EA group, a psycho-intervention(PI) group and a comprehensive therapy(EA plus PI) group. Patients in the EA group were treated with EA. Patients in the PI group were treated with cognition and behavior therapy. Patients in the EA plus PI group were treated with electro-acupuncture plus psychological intervention. Scores of IAD, scores of the symptom checklist90(SCL-90), latency and amplitude of P50 of AEP were measured before and after ***: The scores of IAD after treatment significantly decreased in all groups(P < 0.05), and thescores of IAD in the EA plus PI group were significantly lower than those in the other two groups(P < 0.05). The scores of SCL-90 assembled and each factor after treatment in the EA plus PI group significantly decreased(P < 0.05). After treatment in the EA plus PI group, the amplitude distance of S1P50 and S2P50(S1-S2) significantly increased(P < 0.05).CONCLUSION: EA combined with PI could relieve the mental symptoms of IAD patients, and the mechanism is possibly related to the increase of cerebrum sense perception gating function.

关键词： internet addiction disorder Electroacupuncture Psychological intervention Obsessive behavior Evoked potentials

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P300 change and cognitive behavioral therapy in subjects with internet addiction disorder A 3-month follow-up study

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Neural Regeneration Research 2011年第26期6卷 2037-2041页

作者： Ling Ge Xiuchun Ge Yong Xu Kerang Zhang Jing Zhao Xin Kong Department of Medical Psychology Shanxi Medical College for Continuing Education Taiyuan 030012 Shanxi Province China Shanxi Cardiovascular Hospital Taiyuan 030024.Shanxi Province China Department of Psychiatry First Hospital of Shanxi Medical University Taiyuan 030001 Shanxi Province China College of Humanities and Social Science Shanxi Medical University Taiyuan 030001 Shanxi Province China

Event-related potential studies of cognitive function in addiction behaviors have focused on the P300 event-related potential component. The current study investigated the association between P300 component and internet addiction disorder. We found that individuals with internet addiction disorder exhibited significantly longer P300 latencies than controls （N2： P = 0.035; P3a： P = 0.031 P3b： P = 0.043） and similar P300 amplitudes compared to control participants. After 3 months of cognitive behavioral therapy, P300 latencies decreased significantly in the P3a and P3b （P3a： P = 0.045; P3b： P = 0.062）. These results suggest that deficits in cognitive function may be involved in internet addiction disorder, and that clinical psychological treatment may be effective.

关键词： internet addiction disorder follow-up study college students event-related potential P300 cognitive behavioral therapy

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Determinants of internet addiction among medical students in Casablanca: a cross-sectional study

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Global Health Journal 2023年第2期7卷 101-109页

作者： Boubacar Traore Yassine Aguilo Samira Hassoune Samira Nani Epidemiology Laboratory Faculty of Medicine and Pharmacy of CasablancaHassan Ⅱ UniversityCasablancaMorocco Kita Health District Regional Directorate of Health and Public Hygiene of KayesKitaMali Laboratory of Cellular and Molecular Pathology/Team“Epidemiology and Histology of Chronic and Cancerous Diseases” Faculty of Medicine and Pharmacy of CasablancaHassan Ⅱ UniversityCasablancaMorocco

Objective:This study aimed to estimate the prevalence and determinants of internet addiction among medical students at the Faculty of Medicine and Pharmacy of Casablanca,***:This was a cross-sectional study conducted among students at the Faculty of Medicine and Pharmacy in Casablanca between October and March *** online questionnaire was administered to students to collect data and internet addiction was assessed by the Young questionnaire.A score threshold≥50 was adopted to define *** and multivariate logistic regression analyses were used to identify factors associated with internet ***:Out of a total of 4093 FMPC students enrolled in the 2020-2021 academic year,506 agreed to participate in this study,including 303 females and 203 *** mean addiction score assessed on the Young scale was(49.08±16.11).The prevalence of internet addiction was 44.5%(225/506,95% CI:40% to 49%).Multiple regression analysis showed that being older than 20 years(OR=0.17,95% CI:0.40 to 0.64),being female(OR=1.70,95% CI:1.04 to 2.78),being in the dissertation year(6th year)(OR=5.17,95% CI:2.23 to 11.44),having a history of psychiatric consultation(OR=2.64,95% CI:1.34 to 5.21),having divorced parents(OR=2.64,95% CI:1.05 to 5.87),use of sleeping medication(OR=2.9,95% CI:1.05 to 3.70),sleep disorders(OR=2.06,95% CI:1.25 to 3.79),sleep deprivation(OR=2.26,95% CI:1.39 to 3.65),excessive daytime sleepiness(OR=5.39,95% CI:2.19 to 13.24),anxiety disorders(OR=1.47,95% CI:1.18 to 2.30),duration of internet connection(>4 h)(OR=11.43,95% CI:4.85 to 27.66),and having frequent conflicts with parents(OR=2.37,95% CI:1.49 to 3.79)and friends(OR=0.26,95% CI:0.11 to 0.65)were independently associated with internet ***:The prevalence of internet addiction among medical students in Casablanca remains *** action on the determinants would be of great value in prevention.

关键词： internet addiction disorder Medical students Associated factors Cross-sectional study Morocco

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Smartphone dependency and its impact on academics among medical and nursing students: A cross-sectional study

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Journal of Integrative Nursing 2022年第1期4卷 30-35页

作者： Rakesh SHARMA Vibhuti VAIDYA Rincy RAJAN Anumol Thottiyil ELDHOSE Hemkala RATRE Hemant Lata RAI Department of Neurosciences Nursing College of NursingAll India Institute of Medical SciencesRishikeshUttarakhandIndia Department of Pediatrics All India Institute of Medical SciencesRaipurChhattisgarhIndia Department of Emergency All India Institute of Medical SciencesRaipurChhattisgarhIndia Obstetrics and Gynecology Nursing Government College of NursingRaipurChhattisgarhIndia

Objective:This study aimed to assess smartphone dependency and its impact on academics among medical and nursing *** and Methods:A cross-sectional study was carried out on Bachelor of Medicine and Bachelor of Surgery(MBBS)and Bachelor of Science in Nursing(BScN)students in a medical teaching *** Smartphone Dependency Scale and self-structured questionnaire on impact of smartphone on academics were used to assess smartphone dependency and its impact on academics.A total of 436 students were selected using the total enumerative sampling *** were analyzed using the descriptive(frequency,percentage,mean,and standard deviation)and inferential(t-test,Chi-square test)***:The mean age of students was 20.6±1.29 years,81%were females,and the mean body mass index score was 21.59±3.41 kg/*** mean impact on academics and smartphone dependency scores was 19.92±7.01 and 48.58±11.46,*** impact on academics had a significant association with student category(P<0.001)and gender(P<0.001).A significant association was found between the impact on academics(P=0.003)and smartphone dependency(P=0.05)with studying ***:The use of smartphones is more among medical *** studying in the first and second years are found to be more dependent on smartphone,which caused a serious impact on their *** appliances have become mandatory in this era of technology,and it is not possible to stop its usage but negative impact of smartphones on students’academic performance needs to be ***,it is mandatory to organize educational seminars and workshops to promote the appropriate use of smartphones.

关键词： internet addiction disorder medical nursing smartphone students

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Instruments Assessing Problematic Use of the internet and Their Associations with Psychological Distress among Ghanaian University Students

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International Journal of Mental Health Promotion 2024年第11期26卷 875-885页

作者： Yu-Ting Huang Daniel Kwasi Ahorsu Emma Sethina Adjaottor Frimpong-Manso Addo Mark DGriffiths Amir H.Pakpour Chung-Ying Lin Institute of Allied Health Sciences College of MedicineNational Cheng Kung UniversityTainan701Taiwan Department of Special Education and Counselling The Education University of Hong KongTai PoNew TerritoriesHong KongChina Department of Behavioural Sciences School of Medicine and DentistryKwame Nkrumah University of Science and TechnologyKumasiAK-4944Ghana International Gaming Research Unit Psychology DepartmentNottingham Trent UniversityNottinghamNG14FQUK Department of Nursing School of Health and WelfareJönköping UniversityJönköpingSE-55111Sweden Biostatistics Consulting Center National Cheng Kung University HospitalCollege of MedicineNational Cheng Kung UniversityTainan701Taiwan Department of Public Health College of MedicineNational Cheng Kung UniversityTainan701Taiwan Department of Occupational Therapy College of MedicineNational Cheng Kung UniversityTainan701Taiwan

Background:The present study evaluated the psychometric properties of Problematic internet Use(PIU)instruments and their correlation with psychological distress and time spent on internet activities among university students in ***:In the present cross-sectional survey design study,520 participants(35.96% female)were recruited with a mean age of 19.55 years(SD=1.94)from several university departments(i.e.,Behavioral Sciences,Materials Engineering,Nursing and Midwifery,and Biochemistry and Biotechnology)of Kwame Nkrumah University of Science and Technology(KNUST)between 19 July and 04 August,*** completed a survey that included the following measures:the Gaming disorder Test(GDT),Gaming disorder Scale for Adolescents(GADIS-A),internet Gaming disorder Scale-Short Form(IGDS9-SF),Bergen Social Media addiction Scale(BSMAS),Smartphone Application Based addiction Scale(SABAS),Nomophobia Questionnaire(NMP-Q),and the external criterion measure:Depression Anxiety Stress Scale-21(DASS-21).Confirmatory factor analysis(CFA)was carried out to evaluate the structure of the ***’s α,McDonald’s ω,and composite reliability were used to evaluate internal *** correlation was used to examine the associations between the scores of instruments assessing PIU,time spent on internet activities,and the level of psychological ***:Model fits confirmed the(i)unidimensional structure of the GDT,BSMAS,SABAS,IGDS9-SF,(ii)two-factor structure of the GADIS-A,and(iii)four-factor structure of the ***,the study found that different types of PIU were significantly associated with psychological distress and time spent on related internet ***:The six instruments validated in the present study demonstrated very good to excellent psychometric properties when applied to university students in *** significant associations between internet-related disorders,time spent on internet-related activities,and ps

关键词： Factor analysis internet addiction disorder psychometrics social media videogames

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Cerebral functional characteristics of internet game addiction with task-state Fmri

Cerebral functional characteristics of Internet game addicti...

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全国第十三次中西医结合影像学术研讨会全国中西医结合影像学研究进展学习班福建省第八次中西医结合影像学术研讨会

作者： Jun Liu Weihui Li Li Zhang Shunke Zhou Yan Zhang Yebin Jiang Chunhong Zhang Lingjiang Li Department of Radiology Second Xiangya HosipitalCentral South University School of Public Administration Central South University Institute of Mental Health Central South University Cancer Center University of MichiganMI 48109USA

OBJECTIVE:internet gaming addiction(IGA),as a subtype of internet addiction disorder(IAD),is rapidly becoming a prevalent mental health concern around the *** pathogenesis of IAD,however,remains *** study investigated the brain functions in IGA patients with task-state f ***:19 IGA and 19 matched healthy controls participated in this *** all received the stimuli of internet video game play,while the 3.0 Tesla MRI was used to record the results of echo plannar ***:The internet video game play markedly activated IGA group and control *** actived brain regions of the controls included right superior frontal gyrus,right middle frontal,right inferior frontal gyrus,left insular lobe and right *** group showed actived brain regions that mainly distributed over right medial frontal gyrus,right middle frontal gyrus,superior frontal gyrus,bilateral superior temporal gyrus,left transverse temporal gyrus,right inferior parietal gyrus,right inferior parietal lobule,right precuneus,right posterior *** with control group,IGA group showed increased activation in right superior parietal lobule,right insular lobe,right precuneus,right cingulated gyrus,right superior temporal gyrus,and left *** is a significantly difference in number of activated voxels in the two *** average of 1078 voxels was activated in IGA group while only 232 voxels in control ***:Cue-induced internet video game play activates the vision,space,attention and execution centers composed of occipital temporal parietal and frontal *** brain function is noted in IGA subjects with hypofunction of the frontal *** subjects show laterality activation of right cerebral hemisphere.

关键词： internet addiction disorder internet game addiction functional MRI internet video game play task-state functional MRI

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