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inorganic imaging nanoprobes for breast cancer diagnosis

Radiation Medicine and Protection 2023年第2期4卷 80-85页

作者： Qi Guo Maosen Hong Tong Wu Lei Chen Guangxin Duan Jianfeng Zeng Ximing Wang Ling Wen Chunhong Hu Department of Radiology Suzhou Dushu Lake HospitalDushu Lake Hospital Affiliated to Soochow UniversityMedical Centre of Soochow UniversitySuzhou 215001China Suzhou Medical College Soochow University Suzhou215123China Center for Molecular Imaging and Nuclear Medicine State Key Laboratory of Radiation Medicine and ProtectionSchool for Radiological and Interdisciplinary Sciences(RAD-X)Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China Department of Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China

Breast cancer is one of the most prevalent cancers worldwide,and early diagnosis and screening are vital to its successful *** medical imaging methods can assist in the early detection of breast cancer,imaging methods that are currently used for clinical diagnosis have drawbacks,such as low sensitivity and *** agents are often used in diagnostic imaging to address these *** agents have attracted considerable attention in recent years due to their unique physicochemical *** these agents,inorganic nanoprobes have been substantially developed through improvements in synthesis techniques and pairings with other organic *** paper mainly summarizes the specific applications of inorganic nanoprobes in the magnetic resonance imaging,fluorescence imaging,radionuclide imaging,and bimodal/multimodal imaging of breast cancer.

关键词： inorganic nanoprobes Breast cancer diagnosis Magnetic resonance imaging Fluorescence imaging Radionuclide imaging

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Recent developments of fluorescence imaging technology in the second near-infrared window

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Biomedical Engineering Communications 2022年第1期1卷 8-23页

作者： Shu-Tong Wu Lin Chen Wei-Wei Kang Qin Liu Meng-Ting Gao Dong-Sheng Li Yao Li Rong Dai Zi-Liang Zheng Institute of Medical Technology Shanxi Medical UniversityTaiyuan030001China

Background:Fluorescence bio-imaging in the second near-infrared window(NIR-II FL,1000-1700nm)has great potential in clinical theranostics,which is of great importance providing precise locations of lesions and molecular dynamic actions simultaneously in a single ***:T here has been an upsurge of multidisciplinary research focusing on developing functional types of inorganic and organic nanoprobes that can be used for NIR-II FL with the high spatiotemporal resolution,deep tissue penetration,and negligible ***:In this mini-review,we summarize recent progress in inorganic/organic NIR-II FL *** introduce the design and properties of inorganic and organic nanoprobes,in the order of single-walled carbon nanotubes,quantum dots,rare-earth-doped nanoparticles,metal nanoclusters and organic fluorophores,expect to realize precise diagnosis and efficient image-guided ***:Meanwhile,to elucidate the problems and perspectives,we aim to offer diverse biological applications of inorganic/organic NIR-II FL nanoprobes and accelerate the clinical transformation progress.

关键词： second near-infrared biowindow NIR-II fluorescence bio-imaging organic nanoprobes inorganic nanoprobes imaging performance

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