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The evolution of refractive status in Chinese infants during the first year of life and its affected factors

International Journal of Ophthalmology(English edition) 2017年第8期10卷 1290-1294页

作者： Shu-Juan Yu Guo-Hua Liu Yi Liu Jing Huang Ming-Lei Han Bo-dun Zha Zhong-Tao Gai Department of Ophthalmology Qilu Children's Hospital of Shandong University Jinan 250022 Shandong ProvinceChina Pediatric Research Institute Qilu Children's Hospital of Shandong University Jinan 250022 Shandong ProvinceChina Department of Ophthalmology Shandong Provincial Hospital Affiliated to Shandong University Jinan 250021 Shandong Province China

AIM： To study the evolution of the refractive status and examine the affected factors in infants during the first year of life in a large sample size in China. METHODS： A total of 1258 babies （2516 eyes） aged 32wk gestational age to ty participated in the study, including 766 premature and 492 full-term infants. First, each baby received an orthoptic examination, slit-lamp checking and fundus imaging. Patients with diseases which might affect refractive status were excluded from the cohort. The cycloplegia retinoscopy was performed. Their neonatal histories were reviewed. Each measurement contained the refractive status and calculation of the spherical equivalent （SE）. RESULTS： Refractive state showed an average hyperopia of ＋0.94_＋1.63 D at early ages, followed by a trend toward more hyperopia. The refractive state reached the top （＋2.431.46 D） at the age of one to two months. Then gliding till one year old when the refractive state reached ＋0.59：1.41 D. The prevalence of astigmatism was 42.17% in the study, being 2.82% myopic astigmatism and 39.35% hyperopic astigmatism. The 94.1% of hyperopic astigmatism was with-the-rule astigmatism and 71.83% of myopic astigmatism was with-the-rule astigmatism. Refractive state between boys and girls was different. The mean SE of boys was ＋1.97＋1.57 D, while that of girls was ＋1.79＋1.46 D, and the difference was significant. CONCLUSION： Before one year old, the change of refractive status is associated with checking age and sex. At the age of one to two months, the degree of hyperopia reaches the top. Boys have more hyperopic degree than girls, and with- the-rule astigmatism is predominant. Excluding premature infants with advanced retinopathy of prematurity, premature and full-term children have same refraction status.

关键词： refractive status corrected age infant, prematurity spherical equivalent cycloplegic retinoscopy

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