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A new scoring system for assessment of liver function after successful hepatectomy in patients with hepatocellular carcinoma

引用

Hepatobiliary & Pancreatic Diseases International 2011年第3期10卷 265-269页

作者： Zheng-Gui Du,Bo Li,Yong-Gang Wei,Jie Yin,Xi Feng and Xi Chen Department of Liver and Vascular Surgery,West China Hospital,Sichuan University,Chengdu 610041,China Department of Liver and Vascular Surgery West China Hospital Sichuan University Chengdu 610041 China

BACKGROUND:Whether a major liver resection is safe has been judged mainly from the patient’s hepatic ***,a safe limit for liver resection does not exist *** study aimed to construct a new scoring system as a guide to determine a safe limit for liver resection and avoid liver dysfunction after ***:Eighty-six patients with hepatocellular carcinoma who had undergone hepatectomy in West China Hospital from March 2007 to June 2010 were *** patients were classified according to the levels of total bilirubin after hepatectomy and the parameters in the perioperative period were *** operating characteristic (ROC) analysis was made to assess the liver function compensatory (LFC) value to predict liver dysfunction of the patients after *** value is defined as the preoperative KICG value×22.487+standard remnant liver volume (SRLV)×***:Patients were classified into group Ⅰ (normal group,n=69) and group Ⅱ (with total bilirubin >85.5 μmol/L for 7 days after hepatectomy,n=17) based on the levels of total bilirubin after *** II was further divided into two subgroups:recovered subgroup (n=14) and fatal subgroup (n=3).There were no significant differences in preoperative data or intraoperative findings except the indocyanine green test parameters (KICG and ICG R15) and *** analysis showed that the sensitivity and specificity of an LFC value ≤13.01 were 94.1% and 82.6% respectively for predicting liver dysfunction of the patients after ***:The LFC value appears to be a good predictor of postoperative liver dysfunction in patients who undergo hepatectomy for *** expected LFC value of 13.01 seems to be a safe limit for liver resection.

关键词： indocyanine green test standard remnant liver volume hepatectomy liver dysfunction liver function reserve

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